Clinical trials: Obesity and Cardiovascular Risk
Obesity, Childhood, Risk Factor, Cardiovascular
The Svendborg-project
The main aim of this study is to describe differences in development of health and motor performance over time in relation to type of school and other background variables.
- Conditions
- Obesity, Childhood, Risk Factor, Cardiovascular, Sports Injury, Physical Activity
- Trial name
- CHAMPS-DK (NCT03510494)
- Testing
- Augmented physical education program
- Where
- Denmark
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Subclinical Atherosclerotic Cardiovascular Disease, Blood Pressure
Extracellular RNAs in Relation to Cardiometabolic Risk
Background: Extracellular RNAs (exRNAs) send genetic data from cell to cell. This is how they affect the way cells communicate with each other. There are many types of exRNA, and they each serve different roles.
- Conditions
- Subclinical Atherosclerotic Cardiovascular Disease, Blood Pressure, Obesity
- Trial name
- NCT03225196
- Where
- United States
- Volunteers
- 4,495 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Childhood Obesity, Obesity
Lifestyle Interventions and Metabolic Profile in Obese Children
This study evaluates if promotion of a normocaloric and balanced diet and of physical activity, through an individual- or group-based lifestyle intervention of 12 months, may affect anthropometric measurements and metabolic…
- Conditions
- Childhood Obesity, Obesity, Pediatric Obesity, Dyslipidemias
- Trial name
- NCT03728621
- Testing
- Normocaloric and balanced diet, physical activity
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- University of Milan
Insulin Resistance, Atherosclerosis
The Effect of Cranberry Extract Supplementation on Cardiovascular Risk Factors in Obese, Insulin Resistant Humans
The purpose of this study is to determine the health benefits of cranberry extract in people who are at risk for diabetes and heart problems.
- Trial name
- NCT02068144
- Testing
- Cranberry Extract
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cardiovascular Diseases, Obesity
Association Between Abdominal Body Composition, Inflammation, and Risk for Cardiovascular Disease (The MESA ABD Study)
Obesity is a growing public health concern, with approximately 31% of Americans considered obese. The link between abdominal obesity and cardiovascular disease (CVD) has been well established, but the effect of distinct types of…
- Trial name
- MESA ABD (NCT00612365)
- Where
- United States
- Volunteers
- 1,975 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiovascular Disease, Diabetes
Effect of Vitamin D3 Supplementation on Cardiometabolic Risk
Supplementation studies with vitamin D have been performed where cardiometabolic risk markers have been assessed but these are few, and results are inconsistent. Hence, the purpose of this study is to determine: 1.
- Conditions
- Cardiovascular Disease, Diabetes, Bone Disease
- Trial name
- NCT02359214
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Chester
Infant Formula, Growth
Lower Protein Intake and Long-term Risk of Obesity and Cardiovascular Disease
The primary objective of this study is to investigate if consumption of lower protein formula can slow the rate of weight gain of formula-fed infants between 3 and 12 months of age.
- Trial name
- BabyGrowth (NCT03456934)
- Testing
- Modified infant formula, Standard infant formula
- Where
- United Kingdom
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Overweight and Obesity, Weight Loss
Exercise Training and Time-restricted Feeding in Overweight and Obese Adults
Overweight and obesity prevalence in adolescents and adults continues to remain significantly high in the United States. While diet and exercise improve many consequences of obesity, dietary strategies are not always nutrient…
- Trial name
- NCT03823872
- Testing
- Time restricted feeding, Normal feeding
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kyle Hackney
Health, Subjective, Healthy
Prevalence of Sedentary Lifestyle, Pre-hypertension, and Obesity
Hypertension has been a serious problem among people from different ages in the last few decades, so by taking this in consideration we decided to search for specific risk factors that cause hypertension in young healthy adults…
- Trial name
- NCT05629351
- Testing
- Observational Group
- Where
- Turkey (Türkiye)
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Overweight, Obesity
Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk
The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity.
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Healthy
- Trial name
- PINEAPPL (NCT06355544)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Integrative Phenomics
Weight Maintenance, Weight Loss
The SCULPT-Job Cohort Study
This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
- Conditions
- Weight Maintenance, Weight Loss, Stress, Psychological, Job Stress
- Trial name
- SCULPT-Job (NCT06965075)
- Testing
- Diabetes Prevention Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Metabolic Syndrome, Cardiovascular Disease
A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome
The purpose of BEHHS is first to assess the baseline sub-clinical disease in a population of Baptist Health Employees who have Metabolic Syndrome, a known contributor to cardiovascular disease.
- Conditions
- Metabolic Syndrome, Cardiovascular Disease, Atherosclerosis, Obesity
- Trial name
- BEHHS (NCT01912209)
- Testing
- My Everyday Health
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Baptist Health South Florida
Acute Coronary Syndrome, Age Problem
Determining the Age of First Acute Coronary Syndrome
The study aimed to evaluate the association between the obesity grade and the age of the first acute coronary syndrome (ACS). The effect of cardiovascular (CV) risk factors and the age of first ACS in patients with severe obesity…
- Conditions
- Acute Coronary Syndrome, Age Problem, Risk Factor, Cardiovascular
- Trial name
- NCT04578964
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Antalya Training and Research Hospital
Hypertension (HTN), Obesity &Amp; Overweight
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
- Conditions
- Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
- Trial name
- MIND HIIT (NCT07130539)
- Testing
- MIND HIIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Texas Woman's University
Diabetes Mellitus, Type 2, Hypertension
The Effect of Progressive Resistance Exercise Training (PRET) on CVRF in Adults With ID.
Thanks to improved healthcare, the life expectancy of people with ID is increasing and is approaching that of the general population.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Hypercholesterolemia, Obesity
- Trial name
- PRET (NCT06579898)
- Testing
- Progressive resistance exercise training
- Where
- 3 sites in Netherlands
- Volunteers
- 36 people
- Sponsor
- Erasmus Medical Center
Type2diabetes, Heart Failure
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more effective in improving outcomes for individuals with…
- Conditions
- Type2diabetes, Heart Failure, Obesity
- Trial name
- UNLOAD-HF (NCT06364644)
- Testing
- Community Champions, Homegrown Heroes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Obesity, Body Composition
Study of Macronutrients and Heart Disease Risk
The objective of this trial is to examine the long-term effects of a diet low in carbohydrates, as compared to one low in fat, on cardiovascular disease risk factors, including blood pressure (BP), body weight and composition…
- Conditions
- Obesity, Body Composition, Blood Pressure, Cardiovascular Diseases
- Trial name
- MACRO (NCT00609271)
- Testing
- low carbohydrate diet, low fat diet
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Tulane University Health Sciences Center
Insulin Resistance
Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes
Metabolic and cardiovascular diseases are the first cause of morbidity and mortality throughout the world, including Latin America and Colombia.
- Trial name
- NCT03512665
- Testing
- Full dose supplement, Low dose Supplement, Control Oil
- Where
- Colombia
- Volunteers
- 25 people
- Sponsor
- University of Los Andes, Columbia
Haemophilia, Cardiovascular Disease
Cardiovascular Disease (CVD) in Haemophilia
Life expectancy of hemophilia patients has improved considerably during the past decades and is approaching that of the general population.
- Trial name
- NCT01303900
- Where
- 6 sites in Netherlands, United Kingdom
- Volunteers
- 750 people
- Sponsor
- UMC Utrecht