Clinical trials: Obesity and Cardiovascular Risk
Obesity and Cardiovascular Risk
Lifestyle Program Focused on Nourishment, Well-Being, and Health Behaviors in Women With Obesity
Women, Weight and Well-Being is a 12-month research study looking at how a supportive lifestyle program may help women whose weight increases their risk for heart disease.
- Trial name
- NCT07404150
- Testing
- lifestyle change program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Heather Conradson
Diabetes, Cardiovascular Diseases
The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Type 2 Diabetics
The hypothesis of this study is that the daily consumption of 75 g dried apple powder for twelve weeks will improve arterial stiffness and blood pressure by improving endothelial-mediated vasodilation and vascular sympathetic…
- Conditions
- Diabetes, Cardiovascular Diseases, Prediabetes
- Trial name
- NCT02224365
- Testing
- Apple
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida State University
Cardiovascular Diseases, Coronary Disease
20 Year Changes in Fitness & Cardiovascular Disease Risk - Ancillary to CARDIA
To understand the complex, longitudinal relations between physical fitness, physical activity, body mass and composition and fat distribution, and genetic factors and their independent or interactive effects on the development of…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- NCT00106457
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Morbid Obesity, Inactivity
Effect of Physical Activity on Weight Loss and Cardiovascular Risk Factors After Gastric Bypass
The aim of this study is to increase our knowledge about the effect of physical activity in patients who have undergone gastric bypass surgery. The study will provide novel information in two areas.
- Trial name
- NCT01690728
- Testing
- Physical Activity
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity, Cardiovascular Disease
Effects of Physical Activity on Cardiovascular Risk Markers in School-Aged Mexican Children
Childhood obesity is a public health problem; in Mexican children a high prevalence of cardiovascular risk factors are present. Physical activity has been proposed as a strategy to reduce this risk.
- Trial name
- NCT00836446
- Testing
- physical activity
- Where
- Mexico
- Volunteers
- 214 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Obesity, Cardiovascular Risk
School Based Health Promotion Program in Secondary Schools
The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.
- Trial name
- JuvenTUM 3 (NCT00988754)
- Testing
- School children and adolescents as health experts
- Where
- Germany
- Volunteers
- 595 people
- Sponsor
- Technical University of Munich
Type 2 Diabetes, Obesity
Canola-Mediterranean Diet Study in T2DM
The purpose of the study is to assess whether a Mediterranean-type weight-loss diet, enriched with canola oil, high in plant protein, and low in carbohydrates will produce blood sugar control, reduce coronary heart disease (CHD)…
- Conditions
- Type 2 Diabetes, Obesity, Overweight, Cardiovascular Diseases
- Trial name
- NCT02245399
- Testing
- A canola oil enriched mediterranean diet, A high wheat fiber diet
- Where
- 3 sites in Canada
- Volunteers
- 164 people
- Sponsor
- Unity Health Toronto
Cardiovascular Diseases
Mediterranean Diet and Endothelial Function
To assess the effect of Mediterranean diet and some of its specific components (olive oil, non fried fish and nuts) on endothelial function in overweight and obese patients
- Trial name
- NCT01797211
- Testing
- Mediterranean diet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bari
Obesity, Type 2 Diabetes
Effects of Food Cooking on Diabetes-2 Risk Factors
The aim of the project is to investigate the effects of advanced glycation end products (AGEs) formed in food during the cooking process as well as AGEs formed naturally in the human body, on insulin sensitivity and risk factors…
- Conditions
- Obesity, Type 2 Diabetes, Insulin Resistance, Cardiovascular Disease
- Trial name
- Age-2 (NCT01617304)
- Testing
- Dietary intervention
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
Impact of Bariatric Surgery on Nonalcoholic Fatty Liver Disease
The purpose of this study is to investigate the effect of weight loss rate on liver steatosis, steatohepatitis, fibrosis and cardiovascular risk at different stages before and after bariatric surgery.
- Trial name
- NCT01828528
- Testing
- Sleeve gastrectomy
- Where
- Israel
- Volunteers
- 26 people
- Sponsor
- Sheba Medical Center
Obesity, Childhood, Obesity
Low Grade Inflammation in Childhood Obesity : an Independent Risk Factor for Endothelial Dysfunction
Eligible candidates will be recruited within the children with overweight and obesity having a metabolic risk evaluation before treatment in the period 2006 and 2010 at the pediatric clinic of the UZ Brussel In total 60…
- Conditions
- Obesity, Childhood, Obesity, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT04181398
- Testing
- Anthropometry, Blood pressure, Peripheral arterial tonometry
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Kidney Disease, Obesity
Weight Loss Interventions in Obese Patients With Stages 3-4 Chronic Kidney Disease: a Randomised Controlled Trial
Weight loss surgery is the most effective weight loss treatment available, but the direct effect on chronic kidney disease is less widely understood.
- Trial name
- NCT01053130
- Testing
- laparoscopic sleeve gastrectomy, weight management program
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- King's College Hospital NHS Trust
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Hypercholesterolemia, Obesity
The Impact of Using a Smartphone Health Application in the Improvement of Cardiovascular Disease Risk Factors
This study investigates the effectiveness of Mobile health application (mHealth apps) in the improvement of cardiovascular disease risk factors including metabolic and behavioral factors.
- Conditions
- Hypercholesterolemia, Obesity, Diabetes Mellitus, Hypertension
- Trial name
- NCT05798442
- Testing
- smartphone health application (Opulse)
- Volunteers
- 410 people
- Sponsor
- Sultan Qaboos University
Metabolic Syndrome, Diabetes Mellitus
Biomarkers Derived From Adipose Tissue Useful for Diagnosis and Prognosis of Cardiovascular Risk (CVR) in Obese Patient
This study evaluates the relationship between the adipose tissue, as an active component, which can define metabolic phenotypes linked to cardiovascular risk modification post bariatric surgery.
- Conditions
- Metabolic Syndrome, Diabetes Mellitus, Inflammatory Response
- Trial name
- CROP (NCT03561987)
- Testing
- Bariatric surgery
- Volunteers
- 70 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Obesity
Obesity, Weight Loss, and Cardiovascular Disease Risk
The goal of the study is to define the roles played by resistance to insulin-mediated glucose disposal (insulin resistance) and circulating plasma insulin concentrations in: 1) ability to lose weight; 2) reduction of risk for…
- Trial name
- NCT00186459
- Testing
- Hypocaloric diet of varying macronutrient composition
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Adolescent Obesity
Exposure to CARDIovascular Risk Assessed by Cardiac Adiposity in oBese adOlescents Eligible to a Residential Long-term Lifestyle Intervention by Diet and eXercise (CARDIBOX)
The high prevalence of childhood obesity is a major public health issue, worldwide. Childhood obesity is associated with a high risk of cardiovascular events in adulthood, but recent studies also point out the development of…
- Trial name
- CARDIBOX (NCT04310371)
- Testing
- 3-month lifestyle intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Type 2 Diabetes
The Effect of an Alginate Based Beverage on Weight Loss
The project aims to examine the efficacy of a 12-week intake of alginate based ready to drink supplement on development in body weight and body composition, and risk markers for type-2 diabetes and cardiovascular disease in obese…
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- ALGOBES (NCT01231178)
- Testing
- Alginate beverage, Control beverage
- Where
- Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hyperlipidemias, Overweight and Obesity
Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors
The purpose of this study is to conduct a preliminary test of the effectiveness of various educational interventions to promote adoption of a whole-food, plant-strong diet and reduce specific cardiovascular risk factors in…
- Conditions
- Hyperlipidemias, Overweight and Obesity, Diabetes
- Trial name
- NCT03330548
- Testing
- TeleMOVE!, Culinary Rx
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Phoenix VA Health Care System
Insulin Sensitivity, Obstructive Sleep Apnea
Obesity, Sleep Apnea, and Insulin Resistance
Obstructive sleep apnea (OSA) and type 2 diabetes confer increasing economic, social, and public health burdens in the United States.
- Trial name
- NCT02192684
- Testing
- Pioglitazone
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stanford University