Clinical trials: Obesity in Adolescents
Obesity, Myopia
Beijing (Peking)---Myopia and Obesity Comorbidity Intervention (BMOCI)
Based on the RE-AIM framework, this project intends to integrate the prevention and control measures of myopia and obesity, and establish a set of key suitable technical packages and guarantee systems for the…
- Trial name
- NCT05275959
- Testing
- A cluster randomized trial of a comprehensive intervention nesting family and clinic into school centered implementation to reduce myopia and obesity among children and adolescents in Beijing, China
- Where
- 3 sites in China
- Volunteers
- 3,963 people, healthy volunteers welcome
- Sponsor
- Peking University
Obesity
Effect of Different Intensities of Exercise on Daily Energy Expenditure With Physical Activity in Overweight Boys
The main purpose of this study is evaluate the effect of different intensities of exercise (moderate vs. intense) on the daily energy expenditure in overweight adolescents.
- Trial name
- PAPPAS2 (NCT02272088)
- Testing
- physical activity-moderate, Intense physical activity
- Volunteers
- 24 people
- Sponsor
- Rio de Janeiro State University
Hepatic Steatosis, Bariatric Surgery Candidate
Hepatic Mitochondrial Function in Youth
Assess the impact of bariatric surgery on hepatic energy metabolism and glucose and insulin dynamics in obese youth
- Conditions
- Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
- Trial name
- MANGO (NCT03587727)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Obesity, Insulin Resistance
Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth
Vitamin D deficiency is extremely common in obese youth. In our obese population followed in the Endocrinology clinic at Children's Medical Center Dallas, vitamin D levels were inversely correlated with a measure of insulin…
- Conditions
- Obesity, Insulin Resistance, Vitamin D Deficiency
- Trial name
- NCT02168660
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Perrin C White, MD
Health Promotion and Obesity Prevention
The Wildcat Wellness Coaching Trial
Female children (aged 8-13 years) will be recruited through posted flyers, newspaper ads, and word of mouth in the Manhattan, KS area.
- Trial name
- NCT01845480
- Testing
- Wellness coaching
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Obesity
Effectiveness of Adapted Basketball Programs in Adolescents With Obesity (ABBA)
This study aims to evaluate the effects of different basketball training programs on adolescents with obesity. The objective is to assess how these programs influence body weight, physical fitness, motivation to exercise, and…
- Trial name
- ABBA (NCT07046871)
- Testing
- 1. Intervention Name (Arm 1) Name: Adapted Basketball Program with Video Support Type: Behavioral Description: A 7-week basketball intervention for adolescents with obesity, combining pedagogically a, ADAPT Adapted Basketball Program
- Where
- Tunisia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Pediatric Obesity, Motivational Interviewing
Motivation to Change Lifestyle Habits in Youth With Obesity
Approximately one-third of Canadian children have excess weight, putting them at increased risk of type 2 diabetes, cardiovascular disease, bone and joint problems, and some forms of cancer.
- Trial name
- RMI-Family (NCT03527394)
- Where
- 2 sites in Canada
- Volunteers
- 54 people
- Sponsor
- University of Alberta
Physical Inactivity, Obesity, Childhood
Effectiveness of a Telehealth-based Physical Activity Intervention
This study is a 11 week telehealth intervention focusing on increasing physical activity in adolescents who are receiving medical care for obesity. The participants will be randomized into two groups: control and intervention.
- Trial name
- NCT05123235
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity
Healthy Eating Aerobic and Resistance Training in Youth (HEARTY) Trial
The purpose of this study is to evaluate the effects of resistance training, aerobic training, and combined aerobic and resistance training on percent body fat, measured using Magnetic Resonance Imaging (MRI), in sedentary…
- Trial name
- NCT00195858
- Testing
- aerobic and resistance exercise
- Where
- Canada
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Nutritional and Metabolic Diseases, Child Obesity
The FibreGum Study - Changing the Course of Obesity in Children
The aim of this study is thus to assess the effect of a chewing gum containing fibres on body weight, metabolism and the oral and intestinal microbiomes in a population of obese children.
- Conditions
- Nutritional and Metabolic Diseases, Child Obesity, Adolescent Obesity
- Trial name
- FibreGum (NCT05540678)
- Testing
- FibreGum
- Where
- 2 sites in Switzerland
- Volunteers
- 93 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Obesity, Childhood
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries.
- Trial name
- OBEVIDOS (NCT03516968)
- Testing
- Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os
- Where
- 4 sites in France
- Volunteers
- 68 people
- Sponsor
- Hospices Civils de Lyon
Metabolomics, Obesity
Metabolomic Profiling in Adolescents With Obesity and Diabetes
The purpose of this study is to identify unique metabolite signatures associated with the development of Type 2 diabetes and diabetic kidney disease in children.
- Conditions
- Metabolomics, Obesity, Diabetes, Diabetic Nephropathies
- Trial name
- NCT02145572
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Non-Alcoholic Fatty Liver Disease, Obesity
Effect of L-Citrulline Supplementation on NAFLD in Adolescents With Obesity
One of the comorbidities of obesity is nonalcoholic fatty liver disease (NAFLD). L-citrulline is a non-protein amino acid that has shown positive effects on the degree of fat retention and metabolic profile in NAFLD.
- Trial name
- NCT04871360
- Testing
- L-Citrulline supplement, Carboxymethyl cellulose supplement
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- Universidad de Guanajuato
Diet, Healthy, Adolescent Overweight
Impact an Educational Multimodal Intervention to Improve Healthy Habits in Adolescents.
Background: Adolescence is a critical period to promote healthy habits. Objective: To know the impact that a multimodal educational intervention has on the knowledge and modification of healthy habits (HS) (Mediterranean diet…
- Conditions
- Diet, Healthy, Adolescent Overweight, Child Nutrition Sciences, Exercise
- Trial name
- NCT07065097
- Testing
- A multimodal intervention in which they worked on self-esteem, self-concept and body image and nutrition.
- Where
- 2 sites in Spain
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Obesity, Adolescent
Insulin Resistance, Lipid Profile, CRP, IL-18 and Carotid Intima-Media Thickness (CIMT) Diameter in Obese Adolescents
Carotid intima-media thickness (CIMT) is a marker for detecting endothelium dysfunction, and has become a non-invasive method that is very useful in detecting and evaluating subclinical atherosclerosis in obese children and…
- Trial name
- CIMT (NCT06152068)
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Stress, Eating Behavior
Stress Reactivity Study in Adolescents
The goal of this study was to examine the glucocorticoid and behavioral responses to a psychological stressor in obese African-American and non-Latino white adolescents.
- Trial name
- SRAS (NCT03997149)
- Testing
- Acute Laboratory Stressor, Low affect video
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Asthma in Children, Obesity
Managing AsThma AnD Obesity Related Symptoms (MATADORS) Feasibility Study
The purpose of this 4 week pilot study is to test the use of a mobile application (also commonly referred to as an app) designed to help increase self-management strategies among youth that have asthma and obesity.
- Conditions
- Asthma in Children, Obesity, Obesity, Adolescent, Obesity, Childhood
- Trial name
- MATADORS (NCT05742646)
- Testing
- MATADORS, MATADORS Control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Vitamin D Deficiency
Vitamin D3 Supplementation Pilot Study
The purpose of this research study is to determine whether taking vitamin D, every day, over a 12 week period will improve the vitamin D status, risks for poor heart health, risks for developing type 2 diabetes, and/or muscle…
- Trial name
- NCT01546103
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Overweight and Obesity, Overweight Adolescents
Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults.
This study assesses whether oral supplementation with vitamin D contributes to the reduction of body mass index and lipid profile in adolescents and young adults.
- Conditions
- Overweight and Obesity, Overweight Adolescents, Vitamin D Deficiency
- Trial name
- SIMBAIII (NCT04377386)
- Testing
- 1000 IU D vitamin, 200 IU D vitamin
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Cardiovascular de Colombia