Clinical trials: Obesity in Diabetes
Diabetes Mellitus, Type 2, Childhood Obesity
Behavioral Family Systems Therapy (BFST) for Teens With Type 2 Diabetes
This is a randomized, controlled pilot trial of Behavioral Family Systems Therapy for Teens with Type 2 Diabetes (BFST-DM2), an individual psychological intervention tailored to meet the needs of teens with type 2 diabetes.
- Trial name
- ADAPT (NCT03159221)
- Testing
- BFST for Teens with Type 2 Diabetes
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Nemours Children's Clinic
Fetal Macrosomia, Gestational Diabetes
Regulation Of Maternal Fuel Supply And Neonatal Adiposity
The purpose of this study is to determine whether unrecognized maternal hyperglycemia and postprandial lipemia early or late in gestation predicts excess neonatal adiposity.
- Trial name
- NCT00826904
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes, Obesity
A Prospective, Clinical Trial of the TANTALUS® System in Treatment of Obese to Morbidly Obese Patients
The objectives of this feasibility study are to evaluate the safety and functionality of the TANTALUS System with TANTALUS II IPG, to assess the effect of GCM signal application on trends of HbA1c, blood glucose and body weight…
- Trial name
- NCT00779363
- Testing
- rechargeable TANTALUS II
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- MetaCure (USA), Inc.
Diabetes Type II
A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics
The study is a small pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- SUCCEED (NCT01713764)
- Testing
- Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Comparison of Glycemic Control in Obese Diabetics Using Three Different Pen Needles
Anxiety about needles is a concern commonly expressed by diabetics when beginning insulin therapy. A shorter, thinner pen needle that delivers insulin with the safety and efficacy profile of longer pen needles may appeal to many…
- Trial name
- NCT01231984
- Testing
- 4 mm x 32G Pen Needle, 8mm x 31G Pen Needle, 12.7mm x 29G Pen Needle
- Where
- 10 sites in United States
- Volunteers
- 293 people
- Sponsor
- Becton, Dickinson and Company
Type 2 Diabetes, Overweight or Obesity
Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus
This study is designed to assess the safety and tolerability, pharmacokinetics, and pharmacodynamics of CT-996 in overweight/obese participants and participants with Type 2 Diabetes Mellitus (T2DM).
- Trial name
- NCT05814107
- Testing
- CT-996
- Where
- 2 sites in Australia, Mexico
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Carmot Australia First Pty Ltd
Cardiovascular Diseases, Diabetes Mellitus
CV Disease in Adolescents With Type 2 Diabetes
To study cardiac and vascular structure and function in a population of adolescents with type 2 diabetes mellitus (T2DM) compared to a similar group with obesity alone and a similar non-obese group.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Heart Diseases, Obesity
- Trial name
- NCT00114998
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity, Overweight
Reset: Enhancing Weight Loss in a Digital Intervention
The goal of the Reset trial is to learn about the optimal combination of dietary behavior strategies in a fully digital weight loss intervention. The intervention is designed for adults with overweight or obesity.
- Conditions
- Obesity, Overweight, Weight Loss, Health Behavior
- Trial name
- NCT07032571
- Testing
- Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Stanford University
Cardiovascular Risk Factor, Cardiovascular Diseases
Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
The purpose of this study is to examine whether breaking up prolonged sitting with short regular bouts of walking can reduce blood sugar and cholesterol levels after eating, which are risk markers for Type 2 diabetes and heart…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Physical Activity
- Trial name
- NCT03898206
- Testing
- Breaking up sitting with walking breaks (INT-SIT), Prolonged sitting (SIT)
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Diabetes Mellitus, Type 2, Insulin Resistance
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D™ System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type…
- Trial name
- NCT03953963
- Testing
- HydraSolve T2D™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medality Medical
Diabetes Mellitus, Obesity
Surgical Treatment in Diabetic Patients With Grade 1 Obesity
Surgical Treatment in Diabetic Patients With Grade 1 Obesity
- Trial name
- NCT02949687
- Testing
- ileal interposition with sleeve and sympathectomy
- Volunteers
- 23 people
- Sponsor
- Universidade Positivo
Type2 Diabetes Mellitus, Obesity
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation
Several free fatty acids receptors (FFARs) have been discovered. These have been implicated in metabolic processes and inflammation.
- Trial name
- NCT03062592
- Testing
- Pine nut oil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Healthy Volunteers (Diabetes Mellitus, Type 2)
A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.
NNC0519-0130 is a new medicine which may possibly help participants with type 2 diabetes, as it is expected to lower elevated sugar levels in the blood. The medicine may also lower the appetite.
- Trial name
- NCT05363774
- Testing
- NNC0519-0130
- Where
- 3 sites in Denmark, Germany
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Chronic Diseases, Hypertension
Collection of Blood and Urine Specimens From Volunteers Utilizing Health Examination Services
In summary, the researchers want to construct a longitudinal data bank using voluntary health examination participants. Researchers in the National Taiwan University Hospital (NTUH) campus can utilize these data to clarify the…
- Conditions
- Chronic Diseases, Hypertension, Diabetes, Obesity
- Trial name
- NCT00173940
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Obesity, Insulin Resistance
Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Animal studies have found that vitamin K-dependent proteins matrix Gla protein and osteocalcin beneficially influence lipid and glucose metabolism, respectively.
- Conditions
- Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases
- Trial name
- NCT02959762
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Type 2 Diabetes
Lifestyle Intervention in Obesity, Effect on Diabetes
There are evidence from numerous studies on effect of lifestyle intervention in morbidly obese patients with type 2 diabetes. This study examines the effect of the "Evje-model" on type 2 diabetes.
- Trial name
- NCT00466362
- Testing
- The Evje Model
- Where
- Norway
- Sponsor
- Tor-Ivar Karlsen
PreDiabetes, Overweight and Obesity
Effect of Dairy Product Matrices on Insulin Resistance in People with Overweight and Obesity and Prediabetes
The objective of the study is to determine the effect of dairy product matrices on insulin sensitivity in overweight and obese adults with prediabetes. Females and males (30-65 y) will be recruited from the greater Montreal area.
- Trial name
- NCT06322940
- Testing
- 250 mL serving size, 3.25% fat content, 175 g serving size, ≥2% fat content, 50 g serving size, ≥28% fat content
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Prediabetes or Overweight, Obesity Type 2 Diabetes Mellitus
Real-World Outcomes of Tirzepatide in Pakistani Adults With Obesity, Prediabetes, and Type 2 Diabetes
This is a multicentre, prospective, observational study of the medicine tirzepatide as it is used in routine clinical care in Pakistan.
- Conditions
- Prediabetes or Overweight, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
- Trial name
- TRIBUTE-PK (NCT07809568)
- Where
- 9 sites in Pakistan
- Volunteers
- 330 people
- Sponsor
- Universiti Sains Malaysia
Obesity and Diabetes Mellitus, Type 2
Effect of Tvns in Obesity
Avoid unhealthy foods, walk every day for at least 15 min , sleep well, he should take sessions at its time, family should Avoid disturbances, keep quiet as much as possible, make Analysis recoired before and after interaction.
- Trial name
- TVNS EFFECTS (NCT07334951)
- Testing
- Trans vagus nerve stimulation electrical device.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Obesity or Overweight, Type 2 Diabetes
A Phase Ib Study of AZD5004 in Chinese Participants With Overweight/Obesity With or Without Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the safety, tolerability, and PK of AZD5004 compared with placebo in Chinese participants with overweight/obesity with or without T2DM.
- Trial name
- NCT06988553
- Testing
- AZD5004
- Where
- 6 sites in China
- Volunteers
- 45 people
- Sponsor
- Eccogene