Clinical trials: Obesity in Men
Diabetes, Hepatic Steatosis
Elevated Circulating FFA and Intrahepatic Lipid Content
There is increasing evidence that hepatic lipid content (IntraHepatic Lipid, IHL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events.
- Trial name
- NCT01177332
- Testing
- exercise
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Prevention, Obesity Prevention
Effects of Intact and Hydrolyzed Pea Protein on Food Intake, Glycemic Response and Subjective Appetite
The purpose of this protocol is to study the effects of intact and hydrolyzed yellow pea protein, compared to intact and hydrolyzed whey protein, on satiety, food intake, and glucose metabolism in healthy young men.
- Trial name
- NCT01298154
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight, Obesity
Effect of Chili Pepper Extract on Weight and Fat Loss and Metabolism Increase
The purpose of this study is to test the safety and effectiveness of a purified extract of CH-19 Sweet, containing capsinoids.
- Trial name
- NCT00825838
- Testing
- Chronic consumption of chili pepper extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ajinomoto USA, INC.
Obesity, Metabolic Syndrome
Effects of Exercise on Abdominal Obesity and Risk Factors for Cardiovascular Disease
The investigators will randomize abdominally obese men and women at increased health risk to one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume, low intensity exercise (LVLI), 3) High volume…
- Conditions
- Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00955071
- Testing
- Exercise: LVLI, Exercise: HVLI, Exercise: LVHI
- Where
- Canada
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Queen's University
Obesity & Overweight
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
The primary objective is to assess the safety and tolerability of oral dose ERX1000 in obese subjects.
- Trial name
- NCT07570758
- Testing
- ERX1000
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- ERX Pharmaceuticals
Satiety
Protein Intake and Satiety: a Postprandial Study
Obesity is considered the emerging epidemic of the 21st century, becoming one of the major public health problems. Excessive body weight increases morbidity and mortality risk, while decreases the quality of life and expectance.
- Trial name
- NCT04210544
- Testing
- Experimental dietary protein, Casein, Water
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obesity
Weight Loss Effects on Heart and Blood Vessel Function in Obesity
Obesity is a growing epidemic and is associated with an increased risk of heart attack and stroke. The investigators know that obesity leads to abnormalities in how the blood vessels and the heart function and that these…
- Trial name
- NCT00782262
- Testing
- KicStart™
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Body Composition, Beneficial, Basal Metabolic Rate
Breakfast Meal Replacement
Purpose: To evaluate the effects of replacing breakfast with a high protein, high fat, high fiber meal replacement in overweight individuals, on body composition.
- Conditions
- Body Composition, Beneficial, Basal Metabolic Rate, Satiety, Overweight
- Trial name
- MRP (NCT02482545)
- Testing
- Meal replacement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Game of Stones: A Research Study That Texts Men to Help Them Lose Weight
In 2014, 24% of UK men were obese. However men rarely participate in weight loss programmes. This study looks at whether two interventions which show promise can help obese men lose weight and keep it off.
- Trial name
- NCT03040518
- Testing
- Narrative SMS, Endowment Incentive
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Overweight and Obese Adults, BMI>=23 kg/m2
Role of Leucine on Muscle Preservation During Weight Loss in Older Men
Overweight and obesity are part of a global health epidemic. However, older adults trying to lose weight face a dual challenge: first, muscle mass and strength naturally decline at an accelerating rate with age; second, effective…
- Trial name
- NCT07781410
- Testing
- Protein, Leucine
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Nanyang Technological University
Overweight and Obesity
Mobile Phone Intervention for Physical Activity Maintenance in African American Men (MobileMen)
African American men are at risk of developing chronic disease partly due to low levels of regular physical activity. Studies have been effective in increasing physical activity levels in African American men; however for the…
- Trial name
- NCT03055416
- Testing
- Mobile Men App Prototype
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Overweight, Obesity
Effect of Weight Loss on Reproductive Function in Overweight Men
Obesity has been found to be a risk factor for female infertility. Studies have indicated that obese men often have poor semen quality and require increased time to make partner pregnant.
- Trial name
- NCT00934765
- Testing
- weight loss
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oslo University College
Weight Loss
Active Nutrition Program on Weight Loss
The study will evaluate the impact of the Active Nutrition 60-day program from USANA on weight loss and related measures, such as body composition, physical appearance/body shape, perceived wellness, and biochemical markers of…
- Trial name
- NCT06249698
- Testing
- meal replacements and supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Sexual Dysfunction, Endothelial Dysfunction
Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men
This study aims to compare the effects of 8 months of diet modification, with or without exercise, on weight loss, sexual, urinary and endothelial function, systemic inflammation and quality of life in obese men.
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01642576
- Testing
- weight loss counselling
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Obesity, Physical Inactivity
"GameDay Ready": Evaluating a Behavioral Weight Management Program for Black Men Living in the Rural South
The primary objective of this study is to test the feasibility and acceptability of a 12-week behavioral weight management intervention adapted for Black men living in the rural South.
- Conditions
- Obesity, Physical Inactivity, Diet, Healthy
- Trial name
- NCT05530980
- Testing
- GameDay Ready Program
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity
Assessments of Dietary Restrictions in Young and Elderly Obese Men : Metabolism Obesity Nutrition Age
The prevalence of obesity is growing in elderly with heavy consequences in term of medical complications and mortality, so that this is nowadays an important public health issue.
- Trial name
- MONA (NCT02161926)
- Testing
- dietary restrictions
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Toulouse
Obesity, Overweight
The Acute Effects of Caloric Restriction on Anthropometrics, Metabolism, and Cardiovascular Health in Overweight Adults
The purpose of this study is to document the efficacy of a 3 day intermittent fasting/caloric restriction (IF/CR) using the Plexus® 3 day reset program on body weight as well as regulatory parameters of metabolism and metabolic…
- Conditions
- Obesity, Overweight, Intermittent Fasting
- Trial name
- NCT05422391
- Testing
- 3 day caloric restriction/metabolic reset
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Healthy, Overweight and Obesity
The Impact of Citrus Products on Cardiovascular Health
Epidemiological studies have indicated that the consumption of citrus fruit is inversely associated with the risk of cardiovascular disease.
- Trial name
- NCT03611114
- Testing
- Blood orange juice, Control drink
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Overweight and Obesity
Effects of Juice Plus+® Supplementation on Endothelial Function in Overweight Men
The purpose of the study is to determine the effects of daily ingestion of Juice Plus+® capsules containing Orchard, Garden and Vineyard blends on endothelial function and biomarkers of oxidative stress (oxidized LDL, lipid…
- Trial name
- NCT01533987
- Testing
- Juice Plus
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Griffin Hospital
Weight Loss
Resistant Starch and Whey Protein on Energy Metabolism
Recent evidence shows that dietary supplementation with resistant starch (RS) increases fat catabolism and resting energy expenditure and decreases plasma insulin and glucose responses as well as the gut-derived hormone…
- Trial name
- NCT02418429
- Testing
- waxy maize starch, waxy maize starch and Whey Protein, Resistant Starch
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Skidmore College