Clinical trials: Obesity in Pregnancy
Polycystic Ovary Syndrome, Overweight and Obesity
Weight Loss Intervention in Women With PCOS
The proposed single arm 6 mo. trial will assess the impact of weight loss and fat loss due to a multicomponent remotely-delivered lifestyle intervention on ovulation rates and time-to-ovulation in overweight and obese women with…
- Trial name
- NCT03677362
- Testing
- Weight loss intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kansas Medical Center
Hypertension in Pregnancy, Hypertension
Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia.
- Conditions
- Hypertension in Pregnancy, Hypertension, Obesity
- Trial name
- NCT06466161
- Testing
- Upper Arm Cylindrical Blood Pressure Cuff, Forearm Conical Blood Pressure Cuff
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Northwestern University
Obese, Endometrial Cancer
Evaluating the Effect of Perioperative Caloric Restriction Program on Perioperative Outcomes in Patients With Obesity and Endometrial Cancer
80% of endometrial cancer patients are overweight or obese. Preclinical and clinical data have shown that caloric restriction (CR) protects against organ injury and decreases perioperative morbidity.
- Trial name
- NCT02665962
- Testing
- Perioperative Caloric Restriction Program
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Obesity, Type 2 Diabetes
Lifestyle Management of CKD in Obese Diabetic Patients
The purpose of this randomized clinical trial is to evaluate the efficacy of 3 different technology-supported approaches to engaging 300 individuals with diabetes and concurrent chronic kidney disease in weight loss, dietary…
- Conditions
- Obesity, Type 2 Diabetes, Chronic Kidney Disease (CKD)
- Trial name
- NCT02276742
- Testing
- Social Cognitive Theory, Monitoring
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- NYU Langone Health
Obesity During Pregnancy in Clinical Practice
The Impact of Maternal Obesity on Pregnancy Outcomes in El-Minia Locality
A study will carried out over a period of one year , all obese pregnant women as diagnosed with BMI at the time of 1st ANC visit and before labor ,observation of events during both intra-partum \&postpartum periods it will be…
- Trial name
- NCT02719873
- Testing
- The impact of maternal obesity on pregnancy outcomes
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Minia University
Postpartum Weight Retention, Pregnancy Weight Gain
Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women
The purpose of this study is to compare the effectiveness of H42-HV integrated into home visiting compared with usual home visiting services in reducing postpartum weight retention (difference between pre-pregnancy weight and…
- Conditions
- Postpartum Weight Retention, Pregnancy Weight Gain, Overweight and Obesity, Behavior, Health
- Trial name
- NCT05619705
- Testing
- Healthy for Two-Health Coaching (H42), Maintain Healthy in Pregnancy and Postpartum(mHIPP)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Polycystic Ovarian Syndrome (PCOS)
Time Restricted Feeding Model in Women With Polycystic Ovary Syndrome
This study aims to evaluate the effects of a 16:8 time-restricted feeding (TRF) model on anthropometric, metabolic, and hormonal parameters in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06807775
- Testing
- Dietary Intervention (time-restricted feeding model (16:8)), Dietary Intervention (energy restricted dietary intervention)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Food Allergy
Effect of Mediterranean Diet During Pregnancy on the Onset of Overweight and Obesity in the Offspring
The first 1,000 days of life, from the conception to 24 months, are crucial to achieve long-term health outcomes and represent a strategic period to intervene under prevention and public health perspective.
- Trial name
- PREMEDI (NCT03337802)
- Testing
- mediterranean diet
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Proteinuric Kidney Disease, Diabetic Nephropathy
Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease
Primary Hypothesis: Aldosterone breakthrough will occur at a far lower frequency during renin inhibition (0-10% over 9 months), alone or in combination with an ARB, compared to conventional ARB therapy (35-45% over 9 months).
- Conditions
- Proteinuric Kidney Disease, Diabetic Nephropathy, Hypertensive Nephrosclerosis, IgA Nephropathy
- Trial name
- NCT01129557
- Testing
- Aliskiren, Valsartan
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Columbia University
Sepsis, Pre-Eclampsia
Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.
Procalcitonin is a protein consisting of 116 amino-acids which can rapidly rise under inflammatory conditions and sepsis. More than 20 years ago it has been shown that dipeptidylpeptidase-4 (DPP-4) cleaves procalcitonin from the…
- Conditions
- Sepsis, Pre-Eclampsia, Granulomatosis With Polyangiitis, Microscopic Polyangiitis
- Trial name
- NCT05703802
- Testing
- Procalcitonin-variants ELISA-Assay
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
PCOS (Polycystic Ovary Syndrome), Semaglutide
Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome
To investigate the efficacy of semaglutide in obese infertile women of childbearing age with polycystic ovary syndrome (PCOS), we design this prospective, randomized, open and controlled study.
- Trial name
- NCT05702905
- Testing
- Metformin Hydrochloride 500 MG, Semaglutide, 1.34 mg/mL, Semaglutide, 1.34 mg/mL and Metformin Hydrochloride 500 MG
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Peking University First Hospital
Severe Pre-eclampsia, Magnesium Level
Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy
Comparison of the magnesium level in difference continuous rate in women who were diagnosed severe pre-eclampsia obese
- Trial name
- NCT03661775
- Testing
- Magnesium sulfate administration
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Gestational Diabetes, Obesity
Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
This is a prospective, randomized, placebo controlled study with three parallel arms examining the effects of magnesium supplementation in the second trimester of pregnancy.
- Trial name
- NCT01510665
- Testing
- Magnesium citrate, Dietary modification
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity, Pregnancy
Diet and Physical Activity Counseling and n3-long Chain (PUFA) Supplementation in Obese Pregnant Women
In Chile, 1 out of 4 pregnant women is obese (BMI > 30 kg/m2). This impacts negatively the health of the mother and the offspring during pregnancy.
- Trial name
- MIGHT (NCT02574767)
- Testing
- Lifestyle counseling, PUFA Supplementation, Routine diet & PA
- Where
- Chile
- Volunteers
- 1,002 people
- Sponsor
- University of Chile
C.Delivery; Penetration, Pregnant Uterus, by Instrument, Obesity
Cesarean Wound Closure in Women With BMI 40 or Greater
The purpose of this randomized controlled prospective trial is to guide physicians on the most effective evidenced based skin closure during a cesarean section for the obese gravida, defined as a BMI of 40 or greater.
- Trial name
- NCT02549131
- Testing
- Randomizing to Suture or Staple closure of Cesarean section
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- Pediatrix
Polycystic Ovary Syndrome
A Cooking and Eating Study
Background. The polycystic ovary syndrome (PCOS) is a complex hormonal disorder that presents in susceptible girls around the time of menarche. Females with PCOS have high levels of androgens (e.g., testosterone).
- Trial name
- ACES (NCT01079845)
- Testing
- Nutrition Education, Dietary Counseling, and Cooking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Asthma, Children
Early Risk of Asthma in Children Exposed to In-utero Maternal Obesity
This study seeks a better understanding of the pathogenesis of asthma in early life. The aim of this project is to determine whether the offspring of obese mothers at 3 years of life have increased the risk of asthma compared to…
- Conditions
- Asthma, Children, Obesity, Maternal
- Trial name
- NCT02903134
- Volunteers
- 240 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy
Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension
The goal of this clinical trial is to better understand how different strategies, timing, and enhancements to medically tailored food delivery will address structural inequities in the food environment, empower communities to…
- Conditions
- Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension, Eclampsia; Complicating Pregnancy
- Trial name
- NOURISH-HDP (NCT06445543)
- Testing
- MFeast ENHANCED, MFeast Usual Care
- Where
- United States
- Sponsor
- Johns Hopkins University
Maternal Obesity Complicating Pregnancy, Exercise Addiction
Cytokine and Body Composition's Changes in Overweight/Obese Women
Sincev the adipose tissue as been identified as a metabolic active tissue that produces and regulates pro-inflammatory factors, the investigators studied the relationship between cytokine changes and maternal body composition.
- Conditions
- Maternal Obesity Complicating Pregnancy, Exercise Addiction, High-Risk Pregnancy, Inflammatory Status During Preganancy
- Trial name
- NCT02766426
- Testing
- Lifestyle change program
- Where
- Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia