Clinical trials: Obesity in Pregnancy
Obesity, Infertility, Female
Improved Fertility After Exercise in Overweight/Obese Women
Overweight/obesity is associated with sub-fertility. The investigators will assess if regular exercise training prior to assisted fertilization will improve pregnancy rate in overweight/obese women referred to assisted…
- Trial name
- FertilEX (NCT01933633)
- Testing
- Exercise
- Where
- 2 sites in Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Pregnancy
Electronic-personalized Program for Obesity in Pregnancy to Improve Delivery
The purpose of this study is to assess the efficacy of an electronic-based intervention to help pregnant overweight and obese women gain an appropriate amount of weight and improve their delivery i.e.
- Trial name
- ePPOP-ID (NCT02924636)
- Testing
- ePPOP-ID program
- Where
- France
- Volunteers
- 857 people
- Sponsor
- University Hospital, Lille
Atypical Endometrial Hyperplasia, Progesterone Resistance
GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients
To investigate the efficacy of Gonadotropin-releasing Hormone Agonist (GnRHa) plus letrozole in obese progestin-insensitive atypical endometrial hyperplasia (EAH) patients.
- Conditions
- Atypical Endometrial Hyperplasia, Progesterone Resistance, Obesity
- Trial name
- NCT06390904
- Testing
- GnRH antagonist, Letrozole 2.5mg
- Where
- 2 sites in China
- Volunteers
- 29 people
- Sponsor
- Xiaojun Chen
Obesity
Metformin Versus Orlistat in Obese Polycystic Ovary Syndrome (PCOS) Patients
The purpose of this study is to compare the influence of Orlistat and Metformin on obesity treatment in obese PCOS women.
- Trial name
- NCT01003483
- Testing
- orlistat
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Benign, Premalignant and Malignant Gynecological Disease Confined to the Pelvis
Teleassisted Surgery for Gynecological Disease in Obese Patients - OB-ALFX
Phase II prospective single-institutional study.
- Trial name
- OB-ALFX (NCT02338505)
- Testing
- Telelap ALF-X
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity; Familial, Pregnancy Related
Pre-Pregnancy Weight Loss and Baby Behavior Study
This study will help researchers learn more about how babies respond to bottle nipples with larger or smaller holes. Researchers guess that infants of mothers with obesity who did not lose weight prior to pregnancy will have the…
- Conditions
- Obesity; Familial, Pregnancy Related, Infant Behavior
- Trial name
- NCT06358729
- Testing
- Typical Nipple, Challenging Nipple
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Polycystic Ovary Syndrome (PCOS) Women, Obesity
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that is frequently associated with metabolic features, including obesity.
- Trial name
- NCT06896981
- Testing
- Metformin with Semaglutide
- Where
- Bangladesh
- Volunteers
- 31 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Obesity, Pregnancy Related
Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery
This study investigated the maternal and fetal effects during performance of CSEA in the left lateral decubitus and sitting positions in obese pregnant women undergoing elective cesarean section.
- Conditions
- Obesity, Pregnancy Related, Cesarean Section Complications, Spinal Anaesthetic Poisoning of Undetermined Intent
- Trial name
- NCT04612998
- Testing
- left lateral decubitus position, sitting position, The use of intravenous ephedrine.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
High-Risk Pregnancy
Longitudinal Measures of Leptin in Pregnant Women Who Developed Preeclampsia
Background: Obesity in pregnancy is increasing and is a risk factor for metabolic pathology such as preeclampsia. Leptin is an adipokine which has a direct relationship to obesity.
- Trial name
- NCT01649167
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Overweight or Obesity, Pregnancy Related
Better Lifestyle Counseling for African American Women During Pregnancy
The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.
- Conditions
- Overweight or Obesity, Pregnancy Related, Sleep Disturbances, Sleep Hygiene
- Trial name
- BETTER (NCT05234125)
- Testing
- Better, Birth Prep
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
Obesity, Childhood, Lifestyle Intervention
Obesity-fertility Cohort Study: Protocol for the Assessment of Children Aged 6-12 Years and Their Mothers
Maternal preconception obesity and adverse gestational metabolic health increase the risk of childhood obesity in offspring. A group of investigators from Université de Sherbrooke therefore developed a lifestyle intervention…
- Conditions
- Obesity, Childhood, Lifestyle Intervention, Preconception Care
- Trial name
- NCT06402825
- Testing
- Fit-for-Fertility program
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy Pregnant Women, Obese Pregnant Women
Pregnancy Cohort Study: Pregnancy as a Window to Future Health
The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and…
- Conditions
- Healthy Pregnant Women, Obese Pregnant Women, Gestational Diabetes
- Trial name
- PregWin (NCT06925815)
- Where
- Austria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Polycystic Ovary Syndrome
Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
RCT to investigate whether metformin co-treatment would improve IVF outcomes in overweight and obese women with PCOS.
- Trial name
- NCT02910817
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Infertility, Female
Transvaginal Ultrasonography Guided Embryo Transfer
to evaluate the value of using transvaginal ultrasound guided embryo transfer in obese patients undergoing in vitro fertilization.
- Trial name
- NCT03473028
- Testing
- transabdominal ultrasound guided embryo transfer, transvaginal ultrasound guided embryo transfer
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Kasr El Aini Hospital
Polycystic Ovary Syndrome
Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS)
Our hypothesis is that hyperinsulinemia increases the renal clearance of D-chiro-inositol (DCI) in women with polycystic ovary syndrome (PCOS) and that this leads to a reduction in circulating insulin-stimulated…
- Trial name
- PCOS (NCT00868140)
- Testing
- pioglitazone
- Where
- 2 sites in United States, Venezuela
- Volunteers
- 51 people
- Sponsor
- Virginia Commonwealth University
PREG1, Obesity
Pilot Study: Identification of a Multi-omic Predictive Signature for Preterm Birth in Obese African American Women
1. Determine if the stool or vaginal microbiome and urinary metabolite profiles in a pregnant obese population of African American women differ from their pregnant non-obese counterparts 2.
- Trial name
- NCT03181555
- Testing
- Exploratory
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Baylor University
Obesity, Infertility, Female
Fit-for-Fertility Multicenter Randomized Controlled Trial
Infertility affects approximately 10-15% of couples and one of its important modifiable risk factor is obesity, which affects 19% of Canadian women of reproductive age.
- Trial name
- FFF (NCT03908099)
- Testing
- Fit-For-Fertility program, Standard of care
- Where
- 5 sites in Canada
- Volunteers
- 408 people
- Sponsor
- Université de Sherbrooke
Overweight, Obesity
Impact of Education During Pregnancy in Overweight Pregnant Women
Metabolic environment of the foetus during pregnancy in obese women is altered and the child exposed at an increased risk of obesity. Rapid infancy and childhood weight gain is associated with subsequent obesity.
- Conditions
- Overweight, Obesity, Pregnancy, Childhood Obesity
- Trial name
- ETOIG (NCT00804765)
- Testing
- Therapeutic education, Follow-up
- Where
- France
- Volunteers
- 275 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes, Gestational
Relationship Between Gestational Diabetes Mellitus and Inflammatory Adipocytokins in Obese Mothers and Their Newborn at Delivery
ADIPOGEST study aims at comparing circulating levels of inflammatory adipocytokins and C-reactive protein in obese women and their newborn at delivery whether exposed or not to Gestational Diabetes Mellitus (GDM)
- Trial name
- ADIPOGEST (NCT02905487)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Healthy
Effects of Maternal Obesity on Offspring Brain Development
The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.
- Trial name
- NCT03499587
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute