Clinical trials: Obesity in Pregnancy
Endometrial Cancer, Obesity
Adipocytokines in Endometrial Cancer
The number of women diagnosed with uterine cancer continues to rise each year. Since the early 1990s, there has been almost 55% rise in the United Kingdom (UK). 34% of endometrial cancer can be attributed to obesity.
- Trial name
- NCT04697264
- Testing
- Blood and tissue sample collection from patients
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Surrey
Cardiometabolic Risk, Growth
Maternal Diet, Body Mass Index Trajectories and Cardiometabolic Risk in Early Childhood
This study focused on evaluating the association between adherence to the Mediterranean diet during pregnancy and offspring longitudinal body mass index trajectories and cardiometabolic risk in early-childhood.
- Conditions
- Cardiometabolic Risk, Growth, Childhood Obesity
- Trial name
- NCT03274739
- Volunteers
- 2,762 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Recurrent Pregnancy Loss, Overweight , Obesity
Effects of High-frequency Left Dorsolateral Prefrontal rTMS on Heart-brain Coupling in Women With Recurrent Pregnancy Loss and Elevated BMI
This randomized, sham-controlled mechanistic trial will examine whether a single session of high-frequency repetitive transcranial magnetic stimulation, rTMS, applied to the left dorsolateral prefrontal cortex can modify…
- Conditions
- Recurrent Pregnancy Loss, Overweight , Obesity, Heart-Brain Coupling
- Trial name
- NEURO-CARD-BMI (NCT07561931)
- Testing
- Real repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenyang Medical College
Poly Cystic Ovary Syndrome, Overweight , Obesity
Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)
The primary objective of this study is to investigate the effects of a multidisciplinary intervention, including a targeted adapted physical activity program, on lipid oxidation during a walking exercise in women with overweight…
- Trial name
- SCOPAP (NCT07659392)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Infertility, Female, Obesity
Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial
The purpose of pilot trial is to compare the efficacy of lifestyle intervention, metformin intervention, lifestyle combined with metformin intervention in improving assisted reproductive technology in non-polycystic ovary…
- Conditions
- Infertility, Female, Obesity, Insulin Resistance
- Trial name
- NCT03898037
- Testing
- weight loss intervention, metformin intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Polycystic Ovary Syndrome
Exploring Liver and Muscle Fat Content Using MRI
The aim of our study was to compare the difference of fatty infiltration in liver and muscle using magnetic resonance imaging (MRI) between overweight as well as obese polycystic ovary syndrome (PCOS) cases and body mass index…
- Trial name
- NCT05592080
- Testing
- MRI
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bing He
Obesity, Primary, Incontinence, Urge
The Effect of Incontinence Program Applied to Obese Elderly on Quality of Life, Coping and Loneliness
The goal of this: It was planned in a single-blind randomized controlled pre-test-post-test experimental research design. The aim of this study is to determine the effect of urinary incontinence management program on quality of…
- Conditions
- Obesity, Primary, Incontinence, Urge, Incontinence Stress, Aging
- Trial name
- NCT05892575
- Testing
- improving quality of life, coping with urinary incontinence and kegel exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Severe Pre-eclampsia, Magnesium Level
Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy
Comparison of the magnesium level in difference continuous rate in women who were diagnosed severe pre-eclampsia obese
- Trial name
- NCT03661775
- Testing
- Magnesium sulfate administration
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Hypothalamic Obesity
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
The goal of this trial is to learn how well Setmelanotide works to improve weight reduction, hunger, and quality of life in patients 4 years of age and older with acquired Hypothalamic Obesity (HO).
- Trial name
- NCT05774756
- Testing
- Setmelanotide
- Where
- 28 sites in United States, Canada and 4 more
- Volunteers
- 143 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Chronic Kidney Disease, Diabetes
Diabetes CKD Lifestyle Technology Study
The purpose of this study is to pilot test an mHealth technology-supported behavioral intervention designed to engage patients with diabetes and concurrent chronic kidney disease (CKD) in multiple behaviors which aim to reduce…
- Conditions
- Chronic Kidney Disease, Diabetes, Obesity
- Trial name
- NCT02266823
- Testing
- Social Cognitive Theory
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- NYU Langone Health
Pregnancy Weight Gain, Overweight and Obesity
Fitbit Device Use in Overweight Pregnancy
There are set guidelines for weight gain developed by the Institute of Medicine in pregnancy but about three quarters of women gain an inappropriate weight during pregnancy.
- Trial name
- NCT06226597
- Testing
- Fitbit device
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obesity & Overweight, Diabetes Mellitus, Type 2
Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks
This is a nationwide, multi-center, long-term follow-up study of overweight and obese adults in China. The study aims to recruit approximately 26,000 participants across 39 hospitals to better understand how body weight affects…
- Conditions
- Obesity & Overweight, Diabetes Mellitus, Type 2, Hypertension, Non-alcoholic Fatty Liver Disease (MASLD)
- Trial name
- NCT07884903
- Testing
- No intervention; observational assessment only
- Where
- China
- Volunteers
- 25,974 people
- Sponsor
- Shanxi Bethune Hospital
Polycystic Ovary Syndrome, Obesity
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Weight reduction is the most important treatment target when polycystic ovary syndrome (PCOS) is linked to obesity. Liraglutide (LIRA) in dose of 3 mg was recently approved as an anti-obesity drug.
- Trial name
- NCT02909933
- Testing
- liraglutide, metformin and liraglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Pre-Eclampsia
Role of Vaspin in Pathophysiology of Pre-eclampsia
To investigate the possible role of vaspin and apoptosis in pre-eclamptic obese women . To compare the serum as well as placental level of vaspin in normotensive and severe pre-eclamptic obese women.
- Trial name
- NCT06437535
- Volunteers
- 75 people
- Sponsor
- Assiut University
Obesity, Pregnancy Complications
NT-proBNP Levels and Obesity in Pregnancy
A screening modality to help categorize obese pregnant women as high or low probability for heart failure would be helpful in the evaluation of the obese pregnant women with dyspnea.
- Conditions
- Obesity, Pregnancy Complications, Peripartum Cardiomyopathy
- Trial name
- NCT04049136
- Testing
- NT-proBNP
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Duke University
Obesity, Maternal, Weight Gain, Maternal
The Difference of Weight Gain Tendencies and Obesity During Pregnancy
Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia…
- Conditions
- Obesity, Maternal, Weight Gain, Maternal, Birth Weight, Birth Outcome, Adverse
- Trial name
- NCT06540014
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Chronic Kidney Diseases, Obesity
Cognitive-Behavioral Therapy for Managing Obesity in People With Chronic Kidney Disease
In the study Cognitive-Behavioral Therapy (CBT) for Managing Obesity in People with Chronic Kidney Disease (CKD) the investigators will test whether CBT programme is effective for weight loss and weight maintenance after the…
- Conditions
- Chronic Kidney Diseases, Obesity, Overweight
- Trial name
- NCT05927337
- Testing
- Cognitive Behavioral Therapy (CBT) for managing Obesity
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Pregnancy
Weight Management in Obese Pregnant Underserved African American Women
This project will test a novel lifestyle intervention to help overweight and obese socioeconomically disadvantaged African American women achieve healthy weight control during and after pregnancy and improve the health of their…
- Conditions
- Obesity, Pregnancy, Weight Gain
- Trial name
- LIFE-Moms (NCT01768793)
- Testing
- Standard Parents As Teachers (PAT), Parents As Teachers Plus (PAT+)
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Washington University School of Medicine
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University