Clinical trials: Observation of Neuromuscular Block
Neuromuscular Blockade
OS NMB Depth Measured by Central and Peripheral Monitor.
Comparing during anesthesia in the same patient 2 neuromuscular monitors on the same arm.
- Trial name
- NCT03660891
- Testing
- measuring neuromuscular block
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
Neuromuscular Block Prolonged
Hand Dynamometer and Clinical Tests to Evaluate Neuromuscular Recovery in Atracurium vs Rocuronium
One of the common serious complications in the postoperative phase is Residual the neuromuscular blockade that confused the anesthesia medical team also patients may become uncomfortable, un ability to clear secretion…
- Trial name
- NCT05657756
- Testing
- Randomize clinical trial using hand dynamometer
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Safwa University College
Observation of Neuromuscular Block
Reversal of Neuromuscular Blockade in Diabetic Patients
In this study the investigators aimed to compare the time of antagonism and intensity of effect of sugammadex which is used for antagonism of rocuronium on diabetic and non-diabetic patients.
- Trial name
- NCT02057861
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Duzce University
Deep Neuromuscular Block, Low Pressure
Deep Neuromuscular Block With Low Pressure Pneumoperitoneum in Laparoscopic Abdominal Surgeries
The aim of this study is to evaluate the effect of deep neuromuscular block on postoperative pain, duration of surgery, quality of surgical field, length of recovery room stays, Total amount of rescue analgesic, postoperative…
- Conditions
- Deep Neuromuscular Block, Low Pressure, Pneumoperitoneum, Laparoscopic Abdominal Surgeries
- Trial name
- NCT06242262
- Testing
- Deep neuromuscular block, Moderate neuromuscular block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Anesthesia, General
Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)
The purpose of this study was to demonstrate in adult participants faster recovery from a neuromuscular block induced by either rocuronium or vecuronium after reversal at reappearance of T2 (the amplitude of the first response of…
- Trial name
- NCT00451217
- Testing
- Sugammadex, Neostigmine
- Volunteers
- 198 people
- Sponsor
- Merck Sharp & Dohme LLC
Residual Paralysis
Residual Paralysis in the Post Anesthesia Care Unit: the Association Beetween Residual Neuromuscular Block Risk Prediction Score and the Train-of-Four Ratio. a Prospective Single-Center Open-Label Cohort Study
The reported incidence of rNMB varies between 16% to more than 70 depending on the used definition (train-of-four [TOF] ratio 0.7 or 0.9), type of NMBA, type of reversal agent, and timing of measurements The degree of residual…
- Trial name
- NCT06796777
- Volunteers
- 91 people
- Sponsor
- Assiut University
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Gastric Cancer, Obesity
Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity Patient
This study is designed to evaluate the impact of muscle relaxation during laparoscopic gastrectomy on oncological benefit, especially with obese patients over BMI 25.
- Trial name
- NCT03196791
- Testing
- Sugammadex Sodium
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Korea University Anam Hospital
TOF
Residual Neuromuscular Blockade and PACU Admission
Residual neuromuscular blockade (RNMB) remains an underrecognized postoperative safety concern associated with pulmonary complications, prolonged post-anesthesia care unit stay, and reduced patient satisfaction.
- Trial name
- NCT07758868
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people
- Sponsor
- Ankara Etlik City Hospital
Neuromuscular Block
Deep Neuromuscular Block and Sugammadex Versus Standard of Care on Quality of Recovery in Patient Undergo Elective Laparoscopic Cholecystectomy
Single center, prospective, randomized, single blinded, parallel group and controlled, assessor-blinded trial to compare the impact of Deep neuromuscular block and Sugammadex versus Standard of care on Quality of recovery in…
- Trial name
- NCT02648503
- Testing
- Deep neuromuscular block, Moderate neuromuscular block
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Neuromuscular Blockade, Residual
Incidence of Postoperative Residual Curarization
An incomplete postoperative recovery of neuromuscular function (postoperative residual curarization - PORC) represents a common problem in post-anesthesia care units (PACU), potentially exposing the patient to adverse respiratory…
- Trial name
- PORC (NCT06193213)
- Testing
- measurement of train of four ratio (TOFR) to assess residual neuromuscolar block
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain, Video-assisted Thoracoscopic Surgery
ESP Block, CNP and QoL After VATS
The Erector Spinae Plane Block (ESPB) is an adequate alternative for pain management after video-assisted thoracoscopy surgery (VATS).
- Trial name
- NCT04737902
- Testing
- Erector spinae plane block
- Where
- Colombia
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario San Ignacio
Neuromuscular Blockade
Effect of Magnesium Sulphate on Neostigmine
The purpose of this study is to evaluate the effect of magnesium sulphate on neostigmine-induced reversal of neuromuscular block by rocuronium
- Trial name
- NCT03020706
- Testing
- Magnesium Sulfate, Injectable
- Where
- South Korea
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Colorectal Disorders, Observation of Neuromuscular Block
Effectiveness of Transverse Abdominus Plane Catheter Blocks to Patient-controlled Analgesia in Laparoscopic Colon Resections
The control of postoperative pain has become a major issue in surgery awareness and it is considered an important measurement of patient satisfaction. Improvements in pain relief, including stopping pain before it starts (i.e.
- Trial name
- NCT01592630
- Testing
- 0.2% ropivacaine, Saline
- Where
- 2 sites in United States
- Sponsor
- Stamford Hospital
Neuromuscular Blockade
Impact of iv Dexamethasone on Reversal of Rocuronium-induced Neuromuscular Block by Sugammadex
Sugammadex is used as a reversal drug for rocuronium- or vecuronium-induced neuromuscular block during general anaesthesia. IV dexamethasone is injected as a prophylactic measure against postoperative nausea and vomiting.
- Trial name
- NCT02562417
- Testing
- Normal saline, IV dexamethasone
- Where
- Switzerland
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Residual Neuromuscular Block
Neostigmine Reversal And Neuromuscular Recovery
Patients undergoing surgery often receive paralytic agents (or neuromuscular blocking agents (NMBAs)) to facilitate the procedure. At the end of surgery, the effects NMBAs are reversed with a drug called neostigmine.
- Trial name
- NCT02433808
- Testing
- Neostigmine Group, No Neostigmine group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Neuromuscular Blockade
The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
The aim of this study is to investigate whether an optimized pre-treatment with intravenous magnesium enhances the speed of onset of a standard intubation dose of rocuronium.
- Trial name
- MagRoc (NCT00405977)
- Testing
- Physiologic saline, Magnesium sulphate
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Observation of Neuromuscular Block, Complication of Ventilation Therapy
Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery
The aim of this project is to show, whether the use of the deep neuromuscular block in certain laparoscopic robot-assisted surgery can positively influence main physiological functions compared to the use of standard…
- Conditions
- Observation of Neuromuscular Block, Complication of Ventilation Therapy, Postoperative Recovery
- Trial name
- NCT03420937
- Testing
- Sugammadex, Neostigmine, Atropin Biotika
- Where
- Czechia
- Volunteers
- 138 people
- Sponsor
- University Hospital Olomouc
Postoperative Residual Curarization, Residual Neuromuscular Block
Comparison Between Cisatracurium and Rocuronium in Terms of Recovery of the Muscular Strength in the Postoperative Phase After Surgery and General Anaesthesia
The purpose of this study is to determine the incidence of post-operative residual curarization in our patients and to determine if Cisatracurium and Rocuronium behave differently from each other in terms of residual curarization.
- Trial name
- NCT01651572
- Testing
- Cisatracurium, Rocuronium
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera di Padova
Nephrostomy; Complications, Pneumoperitoneum
A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum
Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation.
- Conditions
- Nephrostomy; Complications, Pneumoperitoneum, Observation of Neuromuscular Block
- Trial name
- LEOPARD-3 (NCT02602964)
- Testing
- Deep neuromsucular block
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Radboud University Medical Center