Clinical trials: Observational Study
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Healthy
Assessing Choice in the Employer Setting (ACES) Study
The purpose of this study is to determine, among adults and in the total population, the effects of offering a choice of FluMist or trivalent inactivated vaccine (TIV) in the employer setting when compared to a control group.
- Trial name
- MA181 (NCT00808808)
- Testing
- Choice of TIV or FluMist with baseline advertisement, Choice of TIV or FluMist with enhanced advertisement and incentives, Control - Usual care offering TIV only with baseline advertisement
- Where
- 47 sites in United States
- Volunteers
- 4,411 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Smoking
The Moment Study: Mixed Method E-cigarette Study
The universe of tobacco products is expanding, with new noncombustible products gaining popularity even as the reduction in prevalence of cigarette smoking slows or stalls.
- Trial name
- Moment (NCT02261363)
- Testing
- Ecig group 1
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Truth Initiative
Alcoholic Hepatitis
Alcoholic Hepatitis Network Observational Study
The purpose of this research study is to create a clinical database and bio-repository. To do this, we will obtain blood, urine, saliva, and stool samples (e.g., biological samples) and personal health information from you to use…
- Trial name
- NCT03850899
- Where
- 9 sites in United States
- Volunteers
- 1,133 people, healthy volunteers welcome
- Sponsor
- Indiana University
Multiple Sclerosis
Effects of Teriflunomide (Aubagio) on Cognitive and Vocational Outcomes in Multiple Sclerosis
Cognitive impairment is common in MS and has devastating impact on functional activities. There is a great demand for medications that will enhance cognitive capacity in MS patients.
- Trial name
- NCT02651545
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Acute Pain
Vasopressin and Pain Perception in the Brain
The feeling of pain is not just a sensory experience, but is also influenced by emotions, beliefs and expectations, making pain a highly subjective experience.
- Trial name
- NCT03446456
- Testing
- Arginine vasopressin, Saline, Observational learning
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Axial Spondyloarthritis, Crohn Disease
MRE as a Screening Tool for axSpA in IBD
This study aims to assess the effectiveness (specificity and sensitivity) of using magnetic resonance enterography (MRE) as a screening tool for axial spondyloarthritis (axSpA) in patients with Crohns disease.
- Trial name
- ProSpA-CD (NCT03817983)
- Testing
- MRE review for evidence of axSpA in SIJs, Clinical assessment and dedicated MRI of the spine and pelvis
- Where
- United Kingdom
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Type2 Diabetes Mellitus
Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D)
The ultimate goal of this field trial is to systematically evaluate a novel care coordination tool for children with Type 2 Diabetes (T2D) in an office setting at Emory/Childrens Healthcare of Atlanta.
- Trial name
- GTG (NCT03926598)
- Testing
- Patient and/or Family Member Intervention, Certified Diabetes Educator Intervention, Physician Intervention
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Dermatitis, Atopic
A Study to Learn About Abrocitinib in Adult Patients With Moderate to Severe Atopic Dermatitis
The purpose of this non-interventional observational study is to learn about the safety and effects of the medicinal product (called Abrocitinib) for the potential treatment of moderate to severe atopic dermatitis (AD).
- Trial name
- NCT05250115
- Where
- 38 sites in Germany
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pfizer
Mild to Moderate Psychopathological Symptoms
The Psychosocial Effects of Systemic / Family Constellation
The purpose of this study is to investigate the psychosocial effects of systemic / family constellation. The method of systemic / family constellation refers to an approach which integrates ideas from family systems therapy with…
- Trial name
- NCT03233958
- Testing
- Systemic / family constellation
- Where
- Hungary
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Károli Gáspár University of the Reformed Church in Hungary
Drying Time
Chlorhexidine Drying Time
Before a patient gets a spinal/epidural, their lower back is cleaned with an antiseptic solution diluted in alcohol called ChloraPrep. ChloraPrep must completely dry before starting the anesthetic procedure.
- Trial name
- Chlorhexidine (NCT02095535)
- Testing
- Chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Papillon-Lefevre Disease
Cytokines in Papillon-Lefèvre Syndrome
Papillon-Lefèvre syndrome (PLS) is characterised by aggressively progressive periodontitis combined with palmo-plantar hyperkeratosis. It is caused by "loss of function" mutations in the cathepsin C gene.
- Trial name
- NCT01116934
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Goethe University
Infant, Premature, Diseases, Infant, Newborn, Diseases
Pulmonary Function Using Non-invasive Forced Oscillometry
The purpose of this observational study is to measure pulmonary function in term and preterm infants with and without pulmonary disease including respiratory distress syndrome, bronchopulmonary dysplasia, transient tachypnea of…
- Conditions
- Infant, Premature, Diseases, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn
- Trial name
- PUFFOR (NCT03346343)
- Testing
- Non-invasive forced airway oscillometry
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cystic Fibrosis
Gut Imaging for Function & Transit in Cystic Fibrosis Study 1
Many people with Cystic Fibrosis (CF) are troubled by symptoms from their stomach and bowels: their gastrointestinal (GI) tract.
- Trial name
- GIFT-CF1 (NCT03566550)
- Testing
- MRI scans
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Vaccines, Pneumococcal Conjugate Vaccine
Post-Marketing Study of the Safety of Prevenar (Pneumococcal Conjugate Vaccine, 7-valent)
To collect post-marketing information on the safety of Prevenar in Filipino patients
- Trial name
- NCT00683410
- Testing
- Pneumococcal Conjugate Vaccine, 7-valent (Prevenar)
- Where
- Philippines
- Volunteers
- 3,366 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
General Safety Profile of DOTAREM
Observational Post-marketing Study on the Safety and Efficacy of Dotarem® (SECURE Study)
The main purpose of this study is to prospectively assess the general safety profile of Dotarem
- Trial name
- NCT01523873
- Where
- 10 sites in Argentina, Austria and 8 more
- Volunteers
- 35,921 people, healthy volunteers welcome
- Sponsor
- Guerbet
Pneumococcal Disease
Postlicensure Observational Safety Study of 13vPnC Administered to Infants and Toddlers
The purpose of the study is to expand the understanding of the safety profile of 13vPnC in routine use following licensure and introduction of the vaccine.
- Trial name
- NCT01128426
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 53,902 people, healthy volunteers welcome
- Sponsor
- Pfizer
Fertility
Validation Study Using a Time-lapse Morphometry MIRI Imaging Incubator
The purpose of this study is to evaluate the safety and efficacy of the MIRI-TL time-lapse incubator and CultureCoin dish compared to standard big-box incubators and standard culture dishes used for embryo culture.
- Trial name
- TiMMI (NCT02852356)
- Testing
- MIRI-TL Incubator
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Menorrhagia
Copper IUD Treatment Observation Study
Studies indicate that bleeding irregularities and dysmenorrhea are common reasons for copper IUD method discontinuation. Some evidence suggests that non-steroidal anti-inflammatory medications (NSAIDs) can help improve bleeding…
- Trial name
- CITROS (NCT02519231)
- Testing
- Naproxen
- Where
- 5 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Atrial Fibrillation, Paroxysmal AF
CARTO® 3 System and Real Time Intracardiac Ultrasound
This is a prospective, multicenter, non-randomized observational study of subjects 18 years and older undergoing RF ablation with drug refractory recurrent symptomatic paroxysmal Atrial Fibrillation (AF).
- Trial name
- IUAF (NCT01716663)
- Testing
- Catheter Ablation
- Where
- 26 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Biosense Webster, Inc.