Clinical trials: Obsessive-Compulsive Disorder (OCD), open to volunteers
- Condition Obsessive-Compulsive Disorder (OCD)
- Status Open to volunteers
- Accepts healthy volunteers yes
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
OCD
Light Therapy for Obsessive-compulsive Disorder (OCD)
The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later).
- Trial name
- KLTO (NCT06720090)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive-Compulsive Disorder
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.
- Trial name
- MKET2 (NCT05940324)
- Testing
- Ketamine, Naltrexone Pill
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
OCD
Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder
This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.
- Trial name
- 3TOC (NCT05843604)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder
Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD
This study aims to explore the efficacy and influencing of accelerated dTMS (deep Transcranial Magnetic Stimulation) treatment in patients with obsessive-compulsive disorder (OCD), and explores the potential neural mechanisms of…
- Trial name
- NCT06692114
- Testing
- Deep Transcranial Magnetic Stimulation, DTMS active
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zhen Wang
ADHD, Obsessive Compulsive Disorder (OCD)
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
- Conditions
- ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
- Trial name
- NCT07566468
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hoarding Disorder, Obsessive-Compulsive Disorder
Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding
Hoarding disorder (HD) is a chronic, progressive, and debilitating psychiatric condition that leads to devastating personal and public consequences, particularly for older adults.
- Trial name
- CREST (NCT05254015)
- Testing
- Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obsessive-Compulsive Disorder
An OCD Prevention Programme for at Risk Adults
The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.
- Trial name
- ØCD (NCT06262464)
- Testing
- Prevention
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Obsessive-Compulsive Disorder
Project EMPOWER-OCD
This research study aims to adapt and evaluate the acceptability and effectiveness of Project EMPOWER-OCD for socioeconomically diverse caregivers of patients with OCD. Designed to reduce obstacles (e.g.
- Trial name
- NCT07158801
- Testing
- Project EMPOWER-OCD, Project CARE
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Obsessive - Compulsive Disorder
Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD
The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17.
- Trial name
- NCT06942494
- Testing
- conventional medical treatment (TAU), Family-Based Self-help Book for Adolescents with Obsessive-Compulsive Disorder
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder (OCD)
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
Obsessive-compulsive disorder (OCD) is associated with substantial impairments in quality of life and is among the most disabling psychiatric disorders.
- Trial name
- NCT06834217
- Testing
- Active transcranial direct current stimulation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive-Compulsive Disorder
Neuroimaging Biomarkers for Predicting rTMS Response in OCD
This study evaluates an accelerated schedule of theta-burst stimulation using a Transcranial Magnetic Stimulation (TMS) device for treatment-resistant Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04286126
- Testing
- Active bilateral DMPFC, Active right-sided OFC
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition affecting 1-3% of the population. Typically, symptoms start in adolescence or early adulthood, are time-consuming, and have a significant impact on quality of…
- Trial name
- NEUROCOMP (NCT06566781)
- Where
- Portugal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundacao Champalimaud
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Brief Culturally Adapted CBT for OCD
The purpose aims to assess the efficacy of Brief Culturally Adapted Cognitive Behaviour Therapy (Ca-CBT) for the treatment of Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT07232823
- Testing
- Brief culturally adapted cognitive behaviour therapy (CaCBT)
- Where
- Pakistan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pakistan Association of Cognitive Therapists
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Obsessive-Compulsive Disorder
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response…
- Trial name
- NCT04131829
- Testing
- Fluoxetine - immediate treatment, Fluoxetine - delayed treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive-Compulsive Disorder, Tic Disorder
Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
This study aims to investigate the characteristics of the microbiota-gut-brain axis in pediatric patients with obsessive-compulsive disorder (OCD) through performing an integrated analysis of gut microbiota, serum metabolomics…
- Trial name
- NCT06754319
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder
Precision Analytic Research Methods in OCD
Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments.
- Trial name
- NCT07011901
- Testing
- Exposure and Response Prevention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai