Clinical trials: Obsessive-compulsive Disorder (OCD)
Panic Disorder, Social Anxiety Disorder
Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
In this multicenter study, the investigators want to find out if an addition of an diagnostic assessment and possibility of treatment with guided self-help CBT can increase the treatment effects of PCBH on patient functioning and…
- Conditions
- Panic Disorder, Social Anxiety Disorder, Depression, Hypochondriasis
- Trial name
- KAIROS (NCT04900064)
- Testing
- Brief interventions, Self-help CBT
- Where
- 4 sites in Sweden
- Volunteers
- 1,242 people
- Sponsor
- Linnaeus University
Obsessive-Compulsive Disorder
Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder
According to the literature the lateral part of the Orbito Frontal Cortex (lOFC) is a relevant bilateral target for repetitive Trans-cranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder (OCD).
- Trial name
- ORBITOC3 (NCT04934007)
- Testing
- rTMS Treatment
- Where
- 2 sites in France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive Compulsive Disorder
Predicting Medication Response in Obsessive Compulsive Disorder
In this study, the investigators hope to study a number of variables the investigators believe may help us predict why some people respond better to some medications than others.
- Trial name
- NCT01404871
- Testing
- clomipramine, escitalopram, duloxetine
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
An ERP-based Mobile Intervention as an Adjunctive Treatment for OCD
The objective of this feasibility study is to evaluate the feasibility, acceptability, and potential usefulness of the investigational device, a mobile software application (app) (OC Free) for treatment of OCD (contamination…
- Trial name
- NCT05166707
- Testing
- BIXINK OC Free
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BIXINK Therapeutics Co., Ltd.
OCD
Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder
The purpose of this study is to provide participants diagnosed with obsessive compulsive disorder (OCD) and completed one of the active study protocols at the Rodriguez Lab, with open/aftercare treatment.
- Trial name
- NCT03511534
- Testing
- Psychotherapy, Pharmacotherapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
A Wearable AI Feedback Tool for Pediatric OCD
To test the feasibility of implementing digitally enhanced psychotherapy and research in a community child and adolescent mental health center including the acceptability of the digital technology to patients, parents and…
- Trial name
- NCT05064527
- Testing
- wearable biosensor, Treatment as usual (TAU), Exposure and response prevention (ERP)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Obsessive-Compulsive Disorder, Tic Disorders
Effects of Ondansetron in Obsessive-compulsive and Tic Disorders
This project investigates the use of 4 weeks of 24 mg/day ondansetron as compared to placebo on symptoms and brain functioning in patients with obsessive-compulsive disorder (OCD) and tic disorders (TD).
- Conditions
- Obsessive-Compulsive Disorder, Tic Disorders, Tourette Syndrome
- Trial name
- NCT03239210
- Testing
- Ondansetron
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- NYU Langone Health
Obsessive Compulsive Disorder (OCD)
Reducing Maximal Support in OCD: Efficacy of Stepped-Care Online CBT
This study is conducted to explore the efficacy and cost-effectiveness of stepped-care internet-based cognitive behavior therapy (sc-ICBT) with reduced support compared to cognitive-behavioral group therapy(CBGT), to identify the…
- Trial name
- NCT06659094
- Testing
- stepped-care Internet-based cognitive behavioral therapy(SC-ICBT), Cognitive Behavioral Group Therapy (CBGT), conventional medical treatment (TAU)
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Shanghai Mental Health Center
OCD, Quality of Life
Evaluation of Capsulotomy by Linear Accelerator Radiosurgery in Severe and Refractory Obsessive-compulsive Disorder
The aim of this study is to evaluate, through a pilot study with about ten cases, if bilateral ventral capsulotomy by linear accelerator enable modification of obsessive-compulsive symptoms and quality of life in patients with…
- Trial name
- NCT02500888
- Testing
- Radiosurgery
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Depressive Disorder, Schizophrenia
Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder
Electroconvulsive therapy (ECT) has unparalleled efficacy in treating severe depression, and is also useful in treatment-refractory cases of schizophrenia and obsessive compulsive disorder (OCD).
- Conditions
- Depressive Disorder, Schizophrenia, Schizoaffective Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT01596608
- Testing
- Magnetic Seizure Therapy (MagPro MST)
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- Centre for Addiction and Mental Health
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT03457675
- Testing
- Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
- Where
- 3 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Schizophrenia
Escitalopram in Schizophrenia in OCD- Open Label Study
SSRI's has been demonstrated to be partially effective in schizophrenia and OCD. We therefore suggest that Escitalopram up to 20 mg /d in those patients could be effective in reducing obsessive compulsive symptomatology
- Trial name
- NCT00456937
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- BeerYaakov Mental Health Center
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive Compulsive Disorder
Neurostimulation and OCD, a MRI Study
This study will focus on the use of repetitive Transcranial Magnetic Stimulation (rTMS) as a treatment of Obsessive Compulsive Disorder (OCD), which is a common illness that impairs quality of life and that can be hard to treat.
- Trial name
- ASLTOC (NCT03918837)
- Testing
- Active rTMS
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospital Center Guillaume Régnier
Obsessive-Compulsive Disorder, Anxiety
Music Therapy in Obsessive Compulsive Disorder
Previous studies have highlighted the potential therapeutic benefits of receptive individual music therapy as an adjunct to standard care, in a variety of psychiatric ailments including mood and anxiety disorders.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety, Depression
- Trial name
- NCT02314195
- Testing
- Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Music therapy
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Islamic Azad University, Marvdasht
Obsessive-Compulsive Disorder
The Study of the Pathogenesis and Cognitive Behavioral Group Therapy in Obsessive-Compulsive Disorder
This study intends to explore the pathogenesis of obsessive-compulsive disorder(OCD) by using biological technologies such as genetics and imaging, and to evaluate the efficacy of group cognitive behavioural therapy in OCD among…
- Trial name
- NCT02739061
- Testing
- cognitive behavioral group therapy, sertraline, fluvoxamine, cognitive behavioral group therapy and drug therapy
- Where
- China
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
The Study of Mindfulness Based Cognitive Therapy and Obsessive-Compulsive Disorder
The primary objective of the study is to evaluate the clinical curative effect of MBCT to reduce obsessive and compulsive symptoms.
- Trial name
- NCT03179839
- Testing
- Mindfulness-based Cognitive Therapy, Psycho-education Program, sertraline, fluvoxamine
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Treatment of Obsessive-Compulsive Disorder (OCD) in Children
The purpose of this study is to compare 3 treatments for children with OCD: medication (sertraline, SER) alone vs OCD-specific therapy (Cognitive Behavior Therapy, CBT) vs medication plus therapy.
- Trial name
- NCT00000384
- Testing
- Cognitive Behavior Therapy, Educational Support, Sertraline
- Where
- 2 sites in United States
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder…
- Trial name
- NCT04548609
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital