Clinical trials: Obsessive-compulsive Disorder (OCD)
OCD
Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder
This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.
- Trial name
- 3TOC (NCT05843604)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive - Compulsive Disorder
Efficacy and Influencing Factors of ALIC-NAc Deep Brain Stimulation in Treatment-Refractory Obsessive-Compulsive Disorder
The goal of this clinical trial is to evaluate the efficacy and influencing factors of the combination of the anterior limb of internal capsule and nucleus accumbens (ALIC-NAc) deep brain stimulation (DBS) in patients with…
- Trial name
- NCT07031544
- Testing
- deep brain stimulation
- Where
- 10 sites in China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder, Illness Anxiety Disorder
Study of Dextromethorphan in OCD and Related Disorders
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
- Conditions
- Obsessive-Compulsive Disorder, Illness Anxiety Disorder, Body Dysmorphic Disorders, Somatic Symptom Disorder
- Trial name
- NCT04899687
- Testing
- Fluoxetine, Dextromethorphan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Clinical and Electrophysiological Outcomes of tDCS in Patients With Treatment Resistant OCD
The aim of this study is to analyze the effectiveness of three different montages of transcranial direct current stimulation (tDCS) in treating treatment-resistant OCD.
- Trial name
- NCT05595421
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Obsessive - Compulsive Disorder
Psilocybin for Treatment of OCD-2
Previous research indicates that psilocybin, a drug that changes activity in brain areas believed to be involved in obsessive-compulsive disorder (OCD), might improve treatment for, and improve lives of, people diagnosed with…
- Trial name
- NCT06992999
- Testing
- Low Dose Psilocybin, High Dose Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Francisco A Moreno
Obsessive-Compulsive Disorder
Psycho-education Intervention for Postpartum OCD and it's Influence on Symptom Severity and Treatment Self Referral Rates
The rationale for conducting the experiment including quantitative measures and a description of the method of recruitment: This study provides psycho-educational intervention aimed at raising awareness of post partum…
- Trial name
- NCT03172728
- Testing
- psycho-education pamphlet
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obsessive-Compulsive Disorder
An OCD Prevention Programme for at Risk Adults
The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.
- Trial name
- ØCD (NCT06262464)
- Testing
- Prevention
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Obsessive-Compulsive Disorder
Is There a New Gold Standard for the Treatment of Obsessive-Compulsive Disorder?
Obsessive Compulsive Disorder is a highly debilitating condition with a lifetime prevalence of 2%-3%, and a notable percentage of patients (40-60%) have a partial or no response to medications.
- Trial name
- NCT04436952
- Testing
- H7 coil, Cool D-B80, Exposure Response Prevention (ERP)
- Where
- Canada
- Sponsor
- University of Alberta
Obsessive-Compulsive Disorder and Symptoms
Brief Anxiety Sensitivity Treatment for Obsessive Compulsive Symptoms
Obsessive-compulsive disorder (OCD), characterized by recurrent obsessions and/or compulsions, is a disabling psychiatric condition affecting approximately 2-3% of the population.
- Trial name
- COAST (NCT02635178)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Florida State University
Pediatric Bipolar Disorder, Pediatric OCD
Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder
This will be a 12-week open-label pilot treatment study for children and adolescents (ages 6-17) who meet DSM-IV criteria for bipolar disorder (BPD) and obsessive-compulsive disorder (OCD) who are adequately mood stabilized on a…
- Trial name
- NCT00592852
- Testing
- fluoxetine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD)
Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder
This observational, cross-sectional case-control study evaluates obsessive-compulsive symptoms among adults with substance use disorder compared with a demographically similar control group without substance use disorder.
- Conditions
- Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Behavior, Substance Abuse Disorder
- Trial name
- NCT07395453
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obsessive-Compulsive Disorder
Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and Family Member Experiences
In this study the investigators will use semi-structured interviews to qualitatively analyse patient and family member experiences with either deep brain stimulation or other forms of psychiatric neurosurgery.
- Trial name
- NCT02537795
- Testing
- deep brain stimulation, anterior capsulotomy
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder (OCD)
Neurobehavioral Investigations of Approach Dynamics in the Ventral Striatum
Traditional strategies for diagnosing psychiatric disorders focus on definitions based on constellations of co-occurring symptoms.
- Trial name
- NCT05422469
- Testing
- Medtronic Percept RC neurostimulator
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition affecting 1-3% of the population. Typically, symptoms start in adolescence or early adulthood, are time-consuming, and have a significant impact on quality of…
- Trial name
- NEUROCOMP (NCT06566781)
- Where
- Portugal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundacao Champalimaud
Trichotillomania
Examining Behavior Therapy for Trichotillomania in Children and Adolescents
This study will evaluate a treatment for trichotillomania, or compulsive hair pulling, in children and adolescents.
- Trial name
- NCT00917098
- Testing
- Behavior Therapy, Supportive Counseling
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Childhood Obsessive-Compulsive Disorder, Autism Spectrum Disorders
A Magnetic Resonance Spectroscopic Examination of Children and Adolescents Taking Riluzole for Obsessive-Compulsive Disorder
Background: Obsessive-compulsive disorder (OCD) is a common childhood disorder that often does not respond to standard treatments.
- Trial name
- NCT01019967
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
The purpose of this study is two-fold: first, to observe the effect of one session of repetitive transcranial magnetic stimulation (rTMS) on the error-prediction abilities of patients with obsessive compulsive disorder (OCD) as…
- Trial name
- NCT02541812
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Obsessive-Compulsive Disorder
Valbenazine in Obsessive Compulsive Disorder
The primary aim of the study is to examine the efficacy and safety of valbenazine in adults with moderate to severe obsessive-compulsive disorder (OCD).
- Trial name
- NCT07111988
- Testing
- Valbenazine
- Volunteers
- 30 people
- Sponsor
- University of Chicago