Clinical trials: Obstetric
Rupture of Membranes Prior to Onset of Labor
PROMab Trial: Ampicillin With or Without Gentamicin for Term Prelabour Rupture of Membranes
The goal of this clinical trial is to learn whether adding gentamicin to standard ampicillin prophylaxis can better prevent clinical chorioamnionitis and other maternal and neonatal infectious complications in pregnant women aged…
- Trial name
- PROMab (NCT07563504)
- Testing
- Ampicillin, Ampicillin + gentamicin
- Where
- 3 sites in Malaysia
- Volunteers
- 320 people
- Sponsor
- Sarawak General Hospital
Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position
Maternal Positioning and Occipitoposterior Fetal Position
The aim of the study is to evaluate the efficacy of a specific maternal position to correct fetal position in occipito-posterior during the labor.
- Conditions
- Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position, Dystocia, Fetal Position and Presentation Abnormalities
- Trial name
- NCT01291355
- Testing
- Specific maternal position during the labor
- Where
- 2 sites in Switzerland
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Postpartum Hemorrhage
Postpartum Hemorrhage and Alterations in Uterine Ecostructure
The goal of this observational study is to evaluate the presence of alterations in the ecostructure of the uterus in patients with a positive history of primary postpartum hemorrhage, in order to demonstrate a statistically…
- Trial name
- NCT06781528
- Testing
- Ultrasound evaluation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Breech Presentation; Before Labor
Breech Delivery Skills. Resident Learning Program
Breech delivery is one of the mail topic in emergency obstetrics for Italian Board of Obstetrics and Gynecology. Formal frontal lecture and digital learning represent nowadays the two typical learning methods.
- Trial name
- Breech (NCT06339164)
- Testing
- skills and learning quality in breech delivery
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Breech Presentation, Pregnancy
Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.
BACKGROUND: Between 3-4% of pregnancies carried to term, the fetuses are in breech presentation. The external version is a maneuver gynecological used to turn a breech in cephalic presentation.
- Trial name
- NCT01048398
- Testing
- remifentanil, paracetamol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Neurologic Manifestations, Premature Birth
The Neu-Prem Trial: Neuromonitoring of Preterm Newborn Brain During Birth Resuscitation
The purpose of this study is to characterize the normal brain function of premature infants (23 to 31+6 weeks GA) during birth transition and through the first 72 hours of life.
- Conditions
- Neurologic Manifestations, Premature Birth, Hypoxia-Ischemia, Brain
- Trial name
- Neu-Prem (NCT02605733)
- Testing
- EEG, NIRS
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Sharp HealthCare
Respiratory Distress Syndrome, Newborn
The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study
The purpose of this study is to evaluate the safety and utility of using heliox gas in combination with nasal CPAP in premature infants.
- Trial name
- NCT00739115
- Testing
- Heliox gas
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Hawaii Pacific Health
Post Spinal Shivering
Compair Efficacy of iv Dexmedetomidine & Tramadol for Post Spinal Shivering in Obs Patients Undergoing Cesarean Section
When opposed to GA,SA is recommended during c section. Shivering is more prevalent and inconvenient complication of spinal anaesthesia, with 40 to 70% incidence rate.
- Trial name
- NCT05616364
- Testing
- Dexmedetomidine injection, Tramadol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Bahadur
Neonatal Disease, Parenting
Neonatal Neurobehavioral And Motor Behavior In Ultra Early Physical Therapy Intervention
Investigation of the combination of neonatal neurobehaviourism and motor behavior in the assessment and ultra-early physical therapy intervention of premature neonates and parental support.
- Conditions
- Neonatal Disease, Parenting, Premature Birth
- Trial name
- NCT05565287
- Testing
- ultra early physiotherapy intervention
- Where
- 3 sites in Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Prematurity
The EveryPrem Project: Evaluating the INTER-NDA for Standardized Neurodevelopmental Screening at 2 Years of Age for Children Born Preterm.
Neurodevelopmental follow-up of infants at high-risk such as preterm born is necessary in order to early detect impairments and early start a supportive/therapeutic intervention.
- Trial name
- EveryPrem (NCT05065385)
- Testing
- INTER-NDA
- Where
- Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Giancarlo Natalucci
Preterm Birth
Clinical Grade MIS Device for Cervical Assessment to Predict Preterm Birth
Every year, globally, about 15 million babies are born preterm (before 37 weeks). This number is rising. Preterm birth (PTB) complications are the leading cause of death among children under 5 years of age, responsible for nearly…
- Trial name
- NCT04008485
- Testing
- Magnetic Electric Impedance Spectroscopy Device to predict PTB
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Preterm Labour
Detection of Preterm Labour by Cervical Length
Detection of short cervix by transvaginal ultrasound and its evidence based management to prevent preterm birth .
- Trial name
- NCT04104984
- Testing
- transvaginal ultrasound, Progesterone Vaginal Suppository, cervical cercalage
- Volunteers
- 966 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preterm Birth, Umbilical Cord Clamping
Umbilical Cord Clamping Methods and Stem Cell Counts in Preterm Infants
This study evaluates the effect of different umbilical cord clamping methods on peripheral blood hematopoietic stem cell counts in preterm newborns.
- Trial name
- NCT07385326
- Testing
- Immediate Cord Clamping, Delayed Cord Clamping, Umbilical Cord Milking
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Era Tufan Benli
Placenta Accreta Spectrum
Diagnostic Accuracy of Placental Thickness in Lower Uterine Segment Measured By Ultrasound in Prediction of Placenta Accreta Spectrum in Patients With Placenta Previa. A Diagnostic Test Accuracy Study
Current prenatal diagnosis of placenta accrete spectrum disorders relies on subjective individual interpretations of visual sonographic findings on grayscale and color Doppler imaging.
- Trial name
- NCT05500404
- Testing
- Ultrasound measurment of placental thickness
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams Maternity Hospital
Infant, Premature, Nutrition
Clinical Effects of a Formula With Modified Protein Levels and Fat Blend in Preterm Infants
This study evaluates the effects of infant formula with higher protein level and improved fat blend on growth and feeding tolerance in preterm infants.
- Trial name
- NCT03055052
- Testing
- Standard formula for preterm infants, Formula with higher protein and new fat blend for preterm infants
- Where
- Vietnam
- Volunteers
- 160 people
- Sponsor
- Société des Produits Nestlé (SPN)
Pregnancy Preterm, Neonatal Hypoglycemia
Continuous Glucose Monitoring of Late Preterm Birth After Corticosteroids
Women undergoing late preterm birth are at high risk of delivering a newborn with neonatal hypoglycemia. The investigators plan to monitor interstitial glucose levels prior to delivery in these women in order to develop a better…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Prematurity
- Trial name
- NCT03738293
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Preterm Labor, Preterm Birth
Interest of a Vaginal Swab in Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth
Preterm labor is the first cause of hospitalization during the pregnancy, and at the origin of more than 60 000 births before 37 weeks of amenorrhea every year in France.
- Trial name
- MAPOSURE (NCT03401255)
- Testing
- Partosure test
- Where
- 2 sites in France
- Volunteers
- 341 people
- Sponsor
- Nantes University Hospital
Preterm Birth
Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome
The purpose of this project is to determine the direct impact of sodium supplementation in preterm infants and to see the overall improvement of their growth and health status.
- Trial name
- NCT05546814
- Testing
- Sodium algorithm
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Neonatal Oxygen Desaturation, Premature
Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants
This research study is being done to investigate the effect of changing an infant's body position on how hard the baby works to breathe, the baby's oxygen level, the baby's carbon dioxide level, the baby's lung volume, the baby's…
- Conditions
- Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
- Trial name
- NCT05968586
- Testing
- Body positioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Premature Birth
Single-center Retrospective Study : Developmental Trajectories of Children Born Prematurely Before 32 Weeks Assessed With the Revised Brunet Lézine Scale at 1, 2 and 3 Years
This study will assess professionals in the CHI Créteil neonatal department and the Val de Marne perinatal network to gain a better understanding of the developmental trajectories of children hospitalized at the CHI Créteil, with…
- Trial name
- NCT06731686
- Testing
- Retrospective study
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil