Clinical trials: Obstetric Hemostasis, open to volunteers
Obstetric Hemostasis, Intravascular Hemolysis
Comparison of Efficacy and Safety of Manual Syringing Versus Pneumatic Pressure Bag for Blood Transfusion in Patients Undergoing Cesarean Section With Major Obstetric Hemorrhage
The goal of this clinical trial is to compare the safety and efficacy of manual syringing versus pneumatic pressure bags for blood transfusion in patients experiencing major obstetric hemorrhage during a cesarean section.
- Conditions
- Obstetric Hemostasis, Intravascular Hemolysis, Major Obstetric Hemorrhage, Manual Syringing Transfusion
- Trial name
- NCT07466719
- Testing
- Manual syringing, pneumatic pressure bag
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Aswan University
Hemophilia A, Hemophilia A, Severe
Hemophilia A Research Program
This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood.
- Conditions
- Hemophilia A, Hemophilia A, Severe, Factor VIII (FVIII), FVIII Deficiency
- Trial name
- HARP (NCT07414511)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Premature Infant, Hemostasis
Normal Hemostasis Values in Premature Infants
This study aims to retrospectively determine, in a large cohort of apparently healthy children born before 37 weeks of gestation, the expected values of certain hemostasis parameters from birth to 18 months (when they start…
- Trial name
- PRHEMO (NCT07349251)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Strasbourg, France
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Postpartum Hemorrhage, Coagulation Disorder
SWIFT - SWIss Factor XIII Trial in PPH
The goal of this trial is to determine if postpartum blood loss can be reduced by replenishing coagulation factor XIII (FXIII) at an early stage of postpartum hemorrhage (PPH).
- Conditions
- Postpartum Hemorrhage, Coagulation Disorder, Coagulation Factor Deficiency, Hemorrhage
- Trial name
- SWIFT (NCT06481995)
- Testing
- Fibrogammin
- Where
- 9 sites in Switzerland
- Volunteers
- 988 people
- Sponsor
- Christian Haslinger
Thrombocytopenia, Postpartum Haemorrhage (PPH)
Prediction of Platelet Function Using Viscoelastic Test (ROTEM® Sigma) in Obstetric Anesthesia.
This prospective observational, non-interventional, single-center study aims to evaluate whether the viscoelastic parameter PLTEM, derived from ROTEM® sigma testing (EXTEM-A5 minus FIBTEM-A5), can accurately estimate platelet…
- Trial name
- NCT07616349
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Nicolas Brogly
Severe Postpartum Hemorrhage
Detection of Bleeding Disorders Diagnosed After Vaginal Delivery Complicated by Severe Postpartum Hemorrhage
A cohort study designed to detect bleeding disorders diagnosed in women who experienced severe postpartum hemorrhage after vaginal delivery
- Trial name
- DIDAPPH (NCT06970860)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Hemorrhage, Gastrointestinal Hemorrhage
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding
This observational study will collect information from adult patients in Japan who are treated with Histoacryl® to stop bleeding from arteries in the chest or abdomen, in order to better understand how well the treatment works…
- Conditions
- Hemorrhage, Gastrointestinal Hemorrhage, Hemoptysis, Postpartum Hemorrhage
- Trial name
- HEAL (NCT07753005)
- Testing
- Embolization therapy
- Where
- 11 sites in Japan
- Volunteers
- 176 people
- Sponsor
- Aesculap AG
Effectiveness of Chitosan Covered Gauze to Stop Bleeding in Post-partum Tears, Comparison of the Effect of Chitosan Covered Gauze With Suturing in Terms of Hemostasis in Post-partum Haemorrhagic Tears
EFFECTIVITY OF CHITOSAN COVERED GAUZE IN POSTPARTUM HEMORRHAGIC OBSTETRIC LACERATIONS
This study was planned to investigate the efficacy of different treatment methods that can be used in the treatment of hemorrhagic tears that may occur in the postpartum period.
- Trial name
- NCT06998641
- Testing
- Chitosan-covered-gauze application, Suturation
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Training and Research Hospital