Clinical trials: Obstetrics
Infertility, Female
Uterine Junctional Zone and Its Relation to Adverse Obstetrical Outcomes in Assisted Reproductive Technology
The junctional zone (JZ) is an internal layer of the myometrium, with unique characteristics that allow its visualization as a hypoechogenic structure in three-dimensional (3D) ultrasound.
- Trial name
- NCT05763498
- Where
- 3 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Lisboa Norte
Obesity, Blood Pressure
Alternative Blood Pressure Measurements in OB Patients
The incidence of obesity has been increasing worldwide. In women with obesity, the anthropometric differences in the distribution of subcutaneous tissue can make accurate measurement of blood pressure difficult.
- Trial name
- NCT04291365
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Post Partum Hemorrhage
Ergometrine Versus Oxytocin in the Management of Atonic Post-partum Haemorrhage (PPH) in Women Delivered Vaginally
200 women with PPH will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Ergometrine 400µgm (Methergin® Novartis, Switzerland) and group 2 will receive oxytocin 10 IU…
- Trial name
- NCT02306733
- Testing
- Ergometrine, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Postpartum Hemorrhage, Cesarean Section Complications
Tranexamic Acid in Patients for Caesarian Delivery.
This is a prospective, double-blinded, randomized placebo-controlled trial. The study will be approved by the DUHS institutional review board (IRB) and the trial will be registered at clinical trial registry.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- TXA; CD (NCT05759156)
- Testing
- Tranexamic acid injection
- Where
- Pakistan
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Perineal Trauma
Ward-Level Implementation and Post-Market Clinical Follow-up Study of ASISU Under Routine Clinical Practice
This is a single-center, prospective, non-randomized post-market clinical follow-up study evaluating the implementation and clinical performance of ASISU during routine vaginal childbirth.
- Trial name
- ASISU-PMCF (NCT07844005)
- Testing
- Perineal protection device
- Where
- Denmark
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- oasicare ApS
Procedural Pain
Virtual Reality for Pain Control in US-Guided Obstetric Needle Procedures
This is a single-site randomized controlled pilot study at Mount Sinai Hospital evaluating the effect of virtual reality on procedural pain and anxiety in obstetric patients undergoing ultrasound-guided needle procedures.
- Trial name
- NCT07094451
- Testing
- Virtual Reality, Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obstetrics, Labor
Clinical Feasibility of Computerized Labor Monitor (CLM) -Heart Application (HA)
The study is a feasibility study to check the possibility of tracking the heart rate of the fetus and to translate the outcome to the progress of the labor
- Trial name
- NCT00502918
- Testing
- CLM - HA Continuous Monitoring System Heart Application
- Where
- Israel
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Barnev Ltd
Preterm Birth
Cervical Pessary to Prevent Preterm Singleton Birth in High Risk Population
DESIGN: Observational prospective study. INCLUSION CRITERIA: All women are 18 years old of age or older with high risk for preterm birth, based on clinical history, and between 18.0 weeks and 23.6 weeks of pregnancy.
- Trial name
- NCT04147117
- Testing
- Cervical pessary
- Where
- Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Hospital Sant Joan de Deu
Menstrual Irregularity, Stress Related Disorder
Women's Menstruation During the Covid-19 Pandemic
The COVID-19 crisis has rapidly become the most significant public health crisis of our times. It has particularly impacted healthcare workers (HCW) due to the over-whelming of healthcare resources, as well as a critical absence…
- Conditions
- Menstrual Irregularity, Stress Related Disorder, COVID-19 Pneumonia, Fear
- Trial name
- NCT05197491
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Secons Stage of Labor
The Effect Of Kristeller Maneuver On Maternal And Neonatal Outcome
The use of fundal pressure in management of the second stage of labor is controversial. The aim of this study is both to evaluate the effectiveness of fundal pressure in shortening the second stage of labor and to examine the…
- Trial name
- NCT01939873
- Testing
- KRISTELLER
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Anesthesia, Spinal, Anesthesia, Obstetrical
The Effect of Injection Rate of Local Anesthetic in Caesarean Section
This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included.
- Trial name
- NCT05091294
- Testing
- Local anesthetic injection rate in spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pelvic Pain
Impact of Thermotherapy During Childbirth on Postpartum Perineal Pain (PERISAFE)
Perineal pain is common after vaginal birth. Thermotherapy might be effective to limit postpartum perineal pain, thanks to the effects of local heating or cooling application.
- Trial name
- PERISAFE (NCT04778631)
- Testing
- Heat therapy, Cryotherapy
- Where
- 2 sites in France
- Volunteers
- 115 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor Pain
Spinal Sufentanil for Obstetric Analgesia
Background: This descriptive study was designed to evaluate effects and adverse effects of spinal sufentanil for relief of labor pain in primi- and multiparous women.
- Trial name
- NCT04141527
- Testing
- Spinal analgesia
- Volunteers
- 164 people
- Sponsor
- Lund University
Hemorrhage
Analyzes of Hemorrhagic Obstetric Patients Whose Were Used Fibrinogen
The files of hemorrhagic obstetric patients undergoing surgery and followed in the intensive care unit and using Fibrinogen and blood products were included in the study between January 2015- September 2018 at the Anesthesiology…
- Trial name
- NCT03723200
- Testing
- Fibrinogen and blood products
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Colic, Nephropathy
Neonatal Outcome of Children With Antenatal Colic Hyperechogenicity
Fetal colic hyper-echogenicity is a presenting symptoms for cystinuria lysinuria. A few cases of fetuses with dibasic protein intolerance (more complex prognosis) presented with colic hyper-echogenicity antenatal.
- Trial name
- COLONECHOGENE (NCT04983069)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Reproductive Tract Infections
Evaluation of Immediate v. Delayed CT/NG Test for Treatment in the ED
The purpose of this study is to determine if immediate availability of GeneXpert® CT/NG test results reduces the overtreatment rate for ED patients with suspected gonorrhea or chlamydia and to assess changes in clinician…
- Trial name
- NCT01989130
- Testing
- Roche AMPLICOR CT/NG, Cepheid Xpert CT/NG Test
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Washington University
Obstetrical Brachial Plexus Palsy
Effectiveness and Safety of Early Intramuscular Botulinum Toxin Injections to Prevent Shoulder Deformity in Babies With Obstetrical Brachial Plexus Palsy
In children population with obstetrical brachial plexus palsy (OBPP), shoulder musculoskeletal deformity is the main cause of morbidity, with a loss of range of shoulder motion, pain and a reduction in social participation.
- Trial name
- POPB-TOX (NCT03198702)
- Testing
- Botulinum toxin type A injection
- Where
- 7 sites in France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Brest
Pregnancy Complications
Obstetric Perineal Trauma and Physiotherapy
The main objective is to investigate effects of perineal trauma at birth on women´s health and whether early physiotherapy improves pelvic floor strength.
- Trial name
- NCT02682212
- Testing
- Physiotherapy intervention
- Where
- Iceland
- Volunteers
- 84 people
- Sponsor
- Landspitali University Hospital
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Hypertension, Pregnancy Induced, Hydralazine Adverse Reaction
Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients.
Severe Hypertension in pregnancy demands urgent treatment because of high mortality \& morbidity in obstetric patients. Hydralazine, the most commonly used agent, causes sudden hypo tension and tachycardia.
- Conditions
- Hypertension, Pregnancy Induced, Hydralazine Adverse Reaction, Pre-eclampsia, Pre-eclampsia Superimposed Pre-existing Hypertension
- Trial name
- NCT02050529
- Testing
- Labetalol, Hydralazine
- Where
- Pakistan
- Volunteers
- 190 people
- Sponsor
- Dow University of Health Sciences