Clinical trials: Obstetrics
Delivery Complication
Obstetrical Outcomes for Planned Deliveries in a French Birth Center
The main objective of this work is to study the obstetrical and neonatal outcomes of women who planned to deliver in the birth centre of Nancy.
- Trial name
- NidaModa (NCT05845879)
- Testing
- delivery
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Unspecified Obstetrical Trauma, With Delivery, Emergencies
Observation of Emergency Obstetrical Situations.
The TeamOBS study is an observational study. We analyze actually recordings of obstetric emergencies to get an even better understanding and knowledge of the association between the communication and cooperation and the quality…
- Trial name
- TeamOBS (NCT03453879)
- Testing
- no intervention
- Where
- 2 sites in Denmark
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- TeamOBS
Hypovolemic Shock, Hemorrhage
Non-Pneumatic Anti-Shock Garment for Obstetrical Hemorrhage: Zambia and Zimbabwe
This trial will address the question of whether early application of the Non-pneumatic Anti-Shock Garment (NASG) at the Satellite Health Facility (SHF) level before transport to a Referral Hospital (RH) will decrease maternal…
- Trial name
- NASG (NCT00488462)
- Testing
- non-pneumatic anti-shock garment
- Where
- 5 sites in Zambia, Zimbabwe
- Volunteers
- 887 people
- Sponsor
- University of California, San Francisco
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Hemorrhage, Postpartum, Placenta Previa
Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women With Placenta Previa
Many RCT(randomized controlled trial) studies reported that tranexamic acid reduced blood loss in women who had elective cesareans.
- Trial name
- TRAPP (NCT05811676)
- Testing
- Tranexamic acid, 0.9% sodium chloride
- Where
- 27 sites in China
- Volunteers
- 1,732 people, healthy volunteers welcome
- Sponsor
- Guangzhou Medical University
Microbiome, Recurrent Pregnancy Loss
Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) is defined as 2 or more consecutive miscarriages1 This condition affects about 1-3% of couples during their reproductive years.
- Trial name
- NCT05612620
- Testing
- coulture
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Pain Management, C Section
Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound Infiltration
The goal of this observational study is to learn whether injecting a numbing medicine (levobupivacaine, a local anesthetic) into the surgical wound at the end of a cesarean delivery improves pain control in women who also receive…
- Conditions
- Pain Management, C Section, Obstetric Pain, Levobupivacaine
- Trial name
- LEVO-CS (NCT07859956)
- Testing
- Levobupivacaine, Intrathecal Morphine
- Where
- Colombia
- Volunteers
- 336 people
- Sponsor
- Fundación Santa Fe de Bogota
Labor Dystocia, Labor Complication
The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL)
Appropriate and timely care during birth is critical to the survival and health of women and their babies. In 2020, the World Health Organization (WHO) presented the Labour Care Guide (LCG) as the new recommended tool for…
- Conditions
- Labor Dystocia, Labor Complication, Labor Onset and Length Abnormalities, Labor (Obstetrics)--Complications
- Trial name
- NORWEL (NCT05791630)
- Testing
- the labour care guide (LCG)
- Where
- 10 sites in Norway
- Volunteers
- 23,650 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Obstetrical Brachial Plexus Palsy
Deficits of Strength of the Rotator Muscles of the Shoulder in Children
The purpose of this retrospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder.
- Trial name
- ROTPOPB (NCT03440658)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Anal Sphincter Injury, Obstetrics Trauma
External Phase MRI in Diagnosis of OASI
There is around 60 000 births annually in Finland. Around 1-5% of all vaginal deliveries in Finland complicate in a Grade III- IV perineal tear.
- Trial name
- NCT03039374
- Testing
- Magnetic resonance imaging
- Volunteers
- 53 people
- Sponsor
- University of Turku
Critical Illness, Difficult; Intubation, Postpartum, During Puerperium
Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique
Unexpected difficult airway exposes the patient to serious morbidity and even mortality. The changes in pregnancy and preeclampsia increase the risk of difficult intubation.
- Conditions
- Critical Illness, Difficult; Intubation, Postpartum, During Puerperium, Pre-Eclampsia
- Trial name
- NCT06651879
- Testing
- techniques of ultrasound examination of the airway
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Healthy
Effect of Immersion, Performed Under the Conditions of Obstetrical Dilatation Bath, on Diuresis and Hemodynamic Variables in Young Women
Like in the full immersion, studied in the context of diving, immersion in water causes a cascade of events with hemodynamic and hormonal consequences.
- Trial name
- IMMERSION (NCT02409953)
- Testing
- Lying in a bath during 2 hours, Lying in a bed during 2 hours
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Pregnancy, Cesarean Section
Different Approaches to Maternal Hypotension During Cesarean Section
The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological.
- Conditions
- Pregnancy, Cesarean Section, Anesthesia,Spinal, Hypotension
- Trial name
- NCT00991627
- Testing
- Bupivacaine, Morphine, Lactated Ringer's solution
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Parma
Pelvic Floor Disorders
Urinary Symptoms and the Omission of the Bladder Flap at the Time of Primary Cesarean Delivery
The bladder flap at the time of cesarean delivery is the term used to describe the separation of the bladder from the lower uterine segment by sharply incising the vesico-uterine peritoneum or serosa and using blunt and/or sharp…
- Trial name
- NCT02967913
- Testing
- Bladder flap
- Volunteers
- 70 people
- Sponsor
- National Naval Medical Center
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Emotion Regulation, Stress
The Effect of Emotional Freedom Technique on Perceived Stress and General Self-Efficacy in Nursing Students
The study was conducted to determine the effect of Emotional Freedom Technique (EFT) on perceived stress and general self-efficacy in obstetrics and gynecology nursing lesson in undergraduate nursing students with fear of birth.
- Conditions
- Emotion Regulation, Stress, Self Efficacy
- Trial name
- NCT06323083
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Quality Health Care, Quality Indicators, Health Care
Quality Indicators in Obstetrics
The study examines whether midwives and doctors are familiar with quality indicators in clinical obstetrics and whether these are used as a tool for continuous improvement process.
- Trial name
- QUIG (NCT07157280)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Obstetric Trauma, Anal Sphincter Injury
Anal Incontinence After Obstetrical Anal Sphincter Injury
Obstetrical Anal Sphincter Injury is an identified risk factor for anal incontinence. The mechanisms and the risk factors for anal incontinence in Obstetrical Anal Sphincter Injury women are not well known.
- Conditions
- Obstetric Trauma, Anal Sphincter Injury, Anal Incontinence
- Trial name
- INCONT-LOSA (NCT04940494)
- Testing
- collection of data
- Where
- France
- Volunteers
- 227 people
- Sponsor
- University Hospital, Angers