Clinical trials: Obstructive Apnea
Obstructive Sleep Apnea Syndrome
Cow's Milk Allergy in Infants With Obstructive Sleep Apnea (OSA)
Cow's milk allergy may be involved in the evolution of sleep apnea in infants. The study will assess the effects of specifies diet changes (i.e. non-milk based formula) on the infant.
- Trial name
- NCT00659854
- Testing
- Non milk or soy based formula, milk based formula
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness
Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA).
- Trial name
- NICEPAP (NCT05067088)
- Testing
- CPAP (all patients receive CPAP as part of routine clinical care)
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Yale University
Obstructive Sleep Apnea
Evaluation of a Full Face Mask for the Treatment of Obstructive Sleep Apnea (OSA) in NZ
This investigation is designed to evaluate the performance (leak and comfort) as well as participant's overall acceptance of the investigative full face mask amongst OSA participants.
- Trial name
- NCT02540603
- Testing
- F&P Jupiter Full Face Mask
- Volunteers
- 15 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea, Inflammation
Effect of Continuous Positive Airway Pressure Treatment on Inflammation in Patients With Obstructive Sleep Apnea
The purpose of this study is to evaluate the effects of CPAP treatment on airway and systemic inflammation in obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Inflammation, Continuous Positive Airway Pressure
- Trial name
- NCT00780923
- Testing
- CPAP treatment
- Where
- Japan
- Volunteers
- 43 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Obstructive Sleep Apnea
Validation of the Mutuality Scale in Patients With OSA and Their Partners
Main objective of this study is to assess the psychometric characteristics of the Mutuality Scale both in patients with Obstructive Sleep Apnea Syndrome (OSAS) and in their partners-The association between the mutuality score in…
- Trial name
- VAMOS (NCT05817123)
- Testing
- Questionnaires
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea, Snoring
A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring
The purpose of this research study is to test a new approach for treating patients with obstructive sleep apnea and/or snoring. The new nasal device, nastent (NAS: nasal airway stent), appears to be a useful alternative or…
- Trial name
- NCT02928770
- Testing
- Nastent
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea
Surgical Treatment for Patients With Obstructive Sleep Apnea by Using Da Vinci SP Surgical System
This prospective, interventional, non-randomized, single arm, clinical trial will investigate feasibility and safety of trans-oral robotic surgery using da Vinci SP Surgical System in Taiwan for the surgical treatment of OSA.
- Trial name
- NCT06766760
- Testing
- Da Vinci SP Surgical System, Model SP1098
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Central And Obstructive Apnoeas In Infants
Improved Discrimination Of Central And Obstructive Apnoeas In Infants
Referral of infants to the respiratory sleep disorders breathing team with apnoeas [pauses in their breathing] and apparent life-threatening episodes are frequent.
- Trial name
- NCT04234074
- Testing
- Volusense paediatric monitoring device
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Sleep Apnea Hypopnea Syndrome, COPD
Prevalence of Sleep Disordered Breathing in a Lung Cancer Screening Cohort
Prospective study of sleep disordered breathing in a lung cancer screening cohort.
- Conditions
- Sleep Apnea Hypopnea Syndrome, COPD, Emphysema, Lung Cancer
- Trial name
- SAILS (NCT02687997)
- Testing
- poligraphy
- Where
- Spain
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Obstructive Sleep Apnea
Alterations in Postprandial Glucose and Lipid Metabolism in Patients With Obstructive Sleep Apnea
The purpose of this study is to examine postprandial glucose and lipid metabolism in patients with obstructive sleep apnea.
- Trial name
- NCT00942110
- Testing
- CPAP treatment
- Where
- Japan
- Volunteers
- 58 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Obstructive Sleep Apnea Syndrome
Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use
The primary objective of this randomized clinical trial is to evaluate the role of patient researchers in promoting the resumption of CPAP therapy in apneic patients who had previously stopped CPAP
- Trial name
- NCT04538274
- Testing
- peer-driven intervention
- Volunteers
- 208 people
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnea, Obesity
Exercise Capacity and Daily Physical Activity in Obese Subjects With Treated Obstructive Sleep Apnea
Obesity is very common worldwide and breathing problems at night (obstructive sleep apnea, OSA) are common in obesity. Despite the best treatment, obesity and OSA are linked to early death from heart problems.
- Trial name
- NCT01930513
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- West Park Healthcare Centre
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Fat Metabolism in OSA and COPD
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by an obstruction of the upper airways. The obstruction results in periods of intermittent hypoxia and re-oxygenation, which lead to increased…
- Conditions
- Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Obesity
- Trial name
- NCT02157844
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Sleep Apnea, Obstructive, Brain Injuries, Traumatic
Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury
Background: Obstructive sleep apnea (OSA) is a sleep disorder common among Veterans with moderate-to-severe traumatic brain injury (TBI).
- Trial name
- FISATABI (NCT04221009)
- Testing
- MI and CBT 4-session manualized intervention
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, Healthy Subjects
Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea
This study will be conducted to determine whether lemborexant as compared to placebo decreases the peripheral oxygen saturation during total sleep time in healthy adult and elderly participants after a single dose of treatment…
- Trial name
- NCT03471871
- Testing
- Lemborexant 10 mg, Lemborexant 25 mg
- Where
- 11 sites in United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Sleep Apnea, Obstructive
Humidity Under Continuous Positive Airway Pressure
Heated humidification in CPAP therapy is often not enough to prevent side effects like dryness of nasal mucosa and xerostomia, especially in cases of mouth breathing or mask leakage.
- Trial name
- NCT01462409
- Testing
- RESMed S9 with humidifier H5i and heated tube Climate Line, CPAP without humidification, CPAP with heated humidification
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV
Obstructive Sleep Apnea
Atomoxetine and DAW2022 on OSA Severity
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. In previous research atomoxetine and oxybutynin showed promising effect at reducing OSA severity, however they reduced…
- Trial name
- NCT05350215
- Testing
- Atomoxetine Oral Capsule [Strattera]
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive
Long-term Evaluation of a Nasopharyngeal Airway
This long-term follow-up study will permit continued device use for participants of the parent study (NCT06677151). During study participation the study team will stay in contact with participants as necessary.
- Trial name
- NCT07191314
- Testing
- nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Sleep Apnea, Obstructive
Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores
DES-OSA and P-SAP scores have been validated to detect OSA (Obstructive Sleep Apnea). One item of P-SAP and DES-OSA is the measurement of neck circumference.
- Trial name
- NCT03047421
- Testing
- Comparison of accuracy of DES-OSA and P-SAP scores
- Where
- Belgium
- Volunteers
- 1,682 people
- Sponsor
- Astes
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