Clinical trials: Obstructive Apnea
Sleep Apnea Syndromes, Sleep Apnea, Obstructives
Effect of Exercise Training on Obstructive Sleep Apnea Syndrome Severity
Sleep apnoea affects more than 20% of people over 65 years and is largely underdiagnosed. It does multiply tenfold the occurrence of vascular events, particularly stroke.
- Trial name
- EXESAS (NCT02463890)
- Testing
- Training, Control
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obstructive Sleep Apnea (OSA)
Oral Dynamic Propulsion Appliance in Treatment of Patients With Obstructive Sleeping Apnea
Obstructive Sleep Apnea (OSA) is one of the most prevalent sleep disorders, affecting nearly one billion people worldwide. It is characterized by repeated episodes of complete (apnea) or partial (hypopnea) obstruction of the…
- Trial name
- NCT07414420
- Testing
- dynamic propulsion oral appliance treatment (DPOA), elastic mandibular advancement appliance treatment
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Hypertension, Obstructive Sleep Apnea (OSA)
How Wall Squat Exercise Affects Blood Pressure in People With High Blood Pressure and Treated Sleep Apnea (WALLPRESS)
This study will look at whether a simple exercise called the isometric wall squat can help lower blood pressure in adults who have both hypertension and obstructive sleep apnoea treated with CPAP.
- Trial name
- WALLPRESS (NCT07730879)
- Testing
- Isometric Wall Squat
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Aveiro University
Obstructive Sleep Apnea, Mild Cognitive Impairment
Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive…
- Conditions
- Obstructive Sleep Apnea, Mild Cognitive Impairment, Subjective Cognitive Impairment
- Trial name
- NCT06089096
- Testing
- Home Sleep Apnea test (HSAT)
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea
Questionnaires to Identify Chinese Patients at Risk for Obstructive Sleep Apnea
The purpose of this study is to validate the Berlin questionnaire and STOP-BANG (snore, tired, obstruction, pressure, body mass index (BMI), age, neck, gender) as effective screening tools for Chinese subjects who are suspected…
- Trial name
- NCT01171196
- Where
- Hong Kong
- Volunteers
- 378 people
- Sponsor
- The University of Hong Kong
Sleep Apnea, Obesity
Sleep Apnea-Hypopnea Syndrome and the Pathogenesis of Obesity
The hypothesis of the study is the following: Patients with sleep apnea-hypopnea syndrome have different pattern in the secretion of hormones.
- Trial name
- NCT00456651
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea Syndrome
Predictive Value of Induced Sleep Endoscopy on Surgical Indication in Obstructive Sleep Apnea Syndromes
Obstructive sleep apnea syndrome (OSA) is a pathology that affects 2 to 15% of the French adult population and more than 30% of subjects over 65 years old.
- Trial name
- SOMMEIL_INDUIT (NCT05201222)
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Respiratory Failure Chronic, Obesity Hypoventilation Syndrome
Myocardial Effects of NIV in OHS Patients
Chronic effects of noninvasive ventilation on myocardial function in patients with obesity hypoventilation syndrome (OHS) are scarcely understood.
- Conditions
- Respiratory Failure Chronic, Obesity Hypoventilation Syndrome, Obstructive Sleep Apnea, Cardiac Output, Low
- Trial name
- NCT06486129
- Testing
- Noninvasive ventilation volume targetted
- Where
- Slovakia
- Volunteers
- 13 people
- Sponsor
- Pavol Jozef Safarik University
Obstructive Sleep Apnea
XOR Levels in OSA Patients (XOR-OSA)
The level of xanthine oxidoreductase (XOR) in plasma is associated with oxidative stress and inflammation. Obstructive Sleep Apnea (OSA) is characterized by repeated upper airway obstruction and apneas during sleep, leading to…
- Trial name
- XOR-OSA (NCT06554496)
- Testing
- CPAP Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Medical University
Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2
Effect of CPAP on Myocardial Dysfunction in Type 2 Diabetes Mellitus and Obstructive Sleep Apnea Patients
This study evaluates the effect of the use of nasal CPAP in the cardiac function, measured by strain and TEI index, in patients with type 2 diabetes mellitus, obstructive sleep apnea and obesity.
- Conditions
- Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2, Continuous Positive Airway Pressure, Myocardial Dysfunction
- Trial name
- NCT03221205
- Testing
- Therapeutic CPAP
- Where
- Mexico
- Volunteers
- 78 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Early Onset Alzheimer Disease, Alzheimer Disease
Sleep Apnea in Early to Mid-Stage Alzheimer's Disease
Obstructive sleep apnea (OSA) is much more common in the elderly than in the young; the latest studies show prevalence between 45% and 62% in individuals over 60.
- Conditions
- Early Onset Alzheimer Disease, Alzheimer Disease, Obstructive Sleep Apnea Syndromes
- Trial name
- AZAP (NCT01400542)
- Testing
- CPAP Treatment, No treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)
Major progress has been made in the area of cardiovascular disease, but we believe that further progress will involve mechanistically addressing underlying respiratory causes including chronic obstructive pulmonary disease (COPD)…
- Conditions
- Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
- Trial name
- CRESCENDO-SLP (NCT05237505)
- Testing
- bi-level positive pressure non invasive ventilation, Oxygen gas
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea
The Impact of Sleep Apnea Treatment on Physiology Traits in Chinese Patients With Obstructive Sleep Apnea
The prevalence of OSA is 3.5~4.6% in Chinese adults. OSA leads to repetitive hypoxemia, hypercapnia, and arousal from sleep and is an independent risk factor for hypertension, stroke, coronary artery disease and congestive heart…
- Trial name
- NCT02696629
- Testing
- upper airway surgery, Continues positive airway pressure, education and follow up
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tongren Hospital
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome
Postoperative Complications in Patients With Obesity Hypoventilation Syndrome
Obstructive sleep apnea (OSA) and Obesity-Hypoventilation Syndrome (OHS) are common conditions in obesity, which may influence the prognosis in patients undergoing surgery.
- Conditions
- Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome, Hypercapnia, Post-Op Complication
- Trial name
- OHBE (NCT02980770)
- Where
- Turkey (Türkiye)
- Volunteers
- 999 people
- Sponsor
- Marmara University
Obstructive Sleep Apnea (OSA)
Vent Flow Study of Prototype Nasal CPAP Mask
As continuous positive airway pressure is the treatment choice for OSA, a mask is vital in ensuring the effectiveness of therapy delivery. The study will evaluate the performance of a new mask system with diffuse vent technology.
- Trial name
- GVFECT (NCT02805777)
- Testing
- CPAP mask
- Sponsor
- ResMed
Difficult Intubation, Airway Disease
STOP-Bang Questionnaire: A Predictor of Obstructive Sleep Apnea and Difficult Mask/Intubation?
Difficult airway management remains the leading cause of anaesthesia-related morbidity and mortality. Obstructive sleep apnea syndrome (OSAS) is a warning sign of difficult airway management.
- Trial name
- NCT06247631
- Testing
- STOP BANG
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
OSA - Obstructive Sleep Apnea
BioMAD - A Non-inferiority Study
Evaluation of the effectiveness of a new mandibular advancement device (BioMAD) in the treatment of obstructive sleep apnea.
- Trial name
- BioMAD (NCT07845331)
- Testing
- BioMAD
- Volunteers
- 20 people
- Sponsor
- University of Lausanne Hospitals
Sleep Apnea, Sleep Apnea, Obstructive
Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders
Aims of this research are to detect if an improvement in sleep pattern in patients suffering from obstructive sleep apnea (OSA), produces a reduction in pain and dysfunction in the orofacial area by examining variation in…
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Pain
- Trial name
- NCT04948541
- Testing
- osa treatment, no treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Anna Alessandri Bonetti
Headache Disorder, Sleep Disorder
Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep Apnea
There is a well-documented but poorly understood relationship between headache disorders (e.g. migraine, cluster headaches, awakening headaches, etc.) and sleep disorders.
- Conditions
- Headache Disorder, Sleep Disorder, Obstructive Sleep Apnea
- Trial name
- NCT00520156
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Obstructive Sleep Apnea
Effects of PAP Treatment of OSA in Patients With Heart Failure
The purpose of this study is to see if treatment of OSA with the CPAP device makes a difference to insulin resistance and heart disease.
- Trial name
- OSA-MRI (NCT01136122)
- Testing
- CPAP Treatment
- Where
- United States
- Sponsor
- Ulysses Magalang MD
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