Clinical trials: Obstructive Apnea
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Obstructive Sleep Apnoea, Hypertension
Ambulatory Versus Home Blood Pressure Monitoring in Obstructive Sleep Apnea
Subjects referred to a sleep clinic had polysomnography (PSG), clinic BP measurements, 24-hour ABP monitoring and HBP monitoring using a device (Microlife WatchBP HomeN) that allows daytime (3 days, 2 duplicate readings/day) and…
- Trial name
- OSA (NCT01685736)
- Where
- 2 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Obstructive Sleep Apnea (OSA)
Validation of HC250 and HC240 Series.
This study is designed to determine the effectiveness of two different CPAP devices. One a standard CPAP which has the ability to store comprehensive compliance and efficacy data and the second a auto adjusting CPAP which uses…
- Trial name
- NCT00739011
- Testing
- SleepStyle 254/244 CPAP series CPAP humidifier
- Where
- 2 sites in New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Afib, Sleep Apnea Syndrome, Obstructive
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe…
- Conditions
- Afib, Sleep Apnea Syndrome, Obstructive, CPAP
- Trial name
- SPARTA (NCT07087587)
- Testing
- CPAP
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Sleep Apnea
Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea
The participants whom undergo Polysomnography study (Sleep study) and are found to have mild, moderate or severe Obstructive Sleep Apnea (OSA) will have two consecutive titration nights.
- Trial name
- NCT05475119
- Testing
- Continuous Positive Airway Pressure (CPAP), High Flow Nasal Cannula (HFNC)
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Abdulaziz University
Sleep Apnea Syndromes, Inflammation
The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person's breathing is restricted during sleep. Obese individuals with OSA are at an increased risk of inflammation and heart conditions, but it is unknown…
- Trial name
- NCT00371293
- Testing
- Weight Loss Program, CPAP therapy
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Acetazolamide Add-On Therapy to OSA Surgery
Surgical procedures are routinely performed as an alternative to continuous positive airway pressure treatment in patients with obstructive sleep apnea (OSA). However, the response to surgery is often variable.
- Trial name
- ACTOS (NCT04227093)
- Testing
- Acetazolamide
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea of Adult
A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep
A study on the effects of daridorexant on nighttime respiratory function in patients with severe obstructive sleep apnea (OSA).
- Trial name
- NCT05458193
- Testing
- Daridorexant
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Obstructive Sleep Apnea (OSA)
Effects of Audiovisual Distraction on Desaturation and Airway Intervention in OSA-patients
Patients will be randomly assigned to either one of two groups: 1. Standard of care sedation 2. Audiovisual distraction during surgery and in the recovery room using video goggles and headphones; patients can choose a movie from…
- Trial name
- AVD (NCT03020914)
- Testing
- Audiovisual Distraction
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hypertension, Blood Pressure
Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device
The goal of this clinical trial is to evaluate the feasibility and effectiveness of a ring-type blood pressure measurement device compared to a 24-hour ambulatory blood pressure monitoring device in patients with hypertension or…
- Conditions
- Hypertension, Blood Pressure, Systolic Hypertension, Diastolic Hypertension
- Trial name
- NCT06084065
- Testing
- CART-I Plus
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Obstructive Sleep Apnea
Spinal Morphine for Patients With Obstructive Sleep Apnea
Patients with Obstructive Sleep Apnea (OSA) appear to be especially vulnerable to medications that suppress pharyngeal muscle activity such as general anesthetics and opioids.
- Trial name
- NCT01790971
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
Alesis OSA-1 Obstructive Sleep Apnea Treatment
The goal of randomized clinical trial is to determine if the Alesis OSA-1 low laser light therapy device can reduce apnea-hypopnea index scores and treat sleep apnea in adult participants over the age of 18 who are diagnosed with…
- Trial name
- OSA (NCT06949969)
- Testing
- OSA LLLT treatment device
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Photonica USA, LLC
Adenotonsillar Hypertrophy, Tonsillitis
Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
The purpose of this study is to evaluate a new method of hemostasis, floseal gel, in tonsillectomy and adenoidectomy, with the goal of decreasing post operative and intraoperative morbidity.
- Conditions
- Adenotonsillar Hypertrophy, Tonsillitis, Obstructive Sleep Apnea
- Trial name
- NCT00459927
- Testing
- Floseal tonsillectomy, Coblation tonsillectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructed Sleep Apnea Syndrome in Patient Candidate to Baratric Surgery
Ketogenic Diet and CPAP Previous Bariatric Surgery
Obstructive Sleep Apnea Syndrome (OSAS) and obesity tend to coexist and are often associated with arterial hypertension, dyslipidaemia, and insulin resistance [1].
- Trial name
- NCT03791242
- Testing
- Cpap and ketogenic diet
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- University of Roma La Sapienza
Sleep Apnea Syndromes
Multicenter Study on the Role of Neurodegeneration Biomarkers in Obstructive Sleep Apnea Syndrome With Residual Excessive Daytime Sleepiness.
Excessive daytime sleepiness which still remains after an effective treatment with nocturnal ventilotherapy or with other specific treatments (positional therapy, oro-mandibular devices) in patients with obstructive sleep apnea…
- Trial name
- EDS in OSA (NCT05795270)
- Testing
- Treatment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA)
EURO-STIM Registry
The registry is to measure longitudinal outcomes and adherence of the Inspire System. The goal of the registry is to capture the life cycle of the patient's use of the Inspire System through routine clinical care visits.
- Trial name
- EURO-STIM (NCT06971796)
- Testing
- Inspire UAS System
- Where
- 21 sites in Austria, Belgium and 5 more
- Volunteers
- 1,000 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea
Asthma Outcomes in Children After Adenotonsillectomy
The aim of the study is to assess the effect of adenotonsillectomy on level of asthma control in preschool children with obstructive sleep apnea.
- Trial name
- NCT03842618
- Volunteers
- 60 people
- Sponsor
- Assiut University
Sleep Apnea Syndrome, Obstructive, Dental Education
Sleep Medicine Education in Dental Schools and Residency Programs in Italian Universities
This study aims to assess whether sleep medicine education is provided within Italian undergraduate dental programs (Degree in Dentistry and Dental Prosthetics) and postgraduate specialization programs in Orthodontics and…
- Conditions
- Sleep Apnea Syndrome, Obstructive, Dental Education, Sleep-disordered Breathing
- Trial name
- Sleep-OD (NCT07624110)
- Testing
- Sleep medicine education questionnaire
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstructive Sleep Apnea
AutoSet for Her Clinical Trial Protocol
The purpose of this study is to assess the efficacy and user preference of the Newport AutoSet for Her in female obstructive sleep apnea (OSA) patients.
- Trial name
- NCT01826513
- Testing
- Standard AutoSet algorithm, Modified AutoSet algorithm
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- ResMed
Sleep Apnea
Obersvational Study on Effects of CPAP on Depressive Symptoms in OSAS
The official definition of depression or major depressive disorder, is a psychological disorder which is characterised by a persistent low mood or loss of interest in previously pleasurable activities, for over two weeks.
- Trial name
- COAST (NCT05953025)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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