Clinical trials: Obstructive Chronic Pulmonary Disease
Insomnia, COPD
A Behavioral Therapy for Insomnia Co-existing With COPD
Difficulty falling asleep, staying asleep or poor quality sleep (insomnia) is common in people with chronic obstructive pulmonary disease.
- Conditions
- Insomnia, COPD, Chronic Obstructive Pulmonary Disease, Fatigue
- Trial name
- NCT01973647
- Testing
- Cognitive Behavioral Therapy for Insomnia, COPD Education, Attention Control
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Illinois Chicago
COPD
Assessing Exercise Capacity After PulseHaler™ Treatment in GOLD II-IV COPD Patients
Prospective, sham controlled, interventional study to evaluate the extent to which PulseHaler improves the functional status of Chronic Obstructive Lung Disease (GOLD) II-IV Chronic obstructive pulmonary disease (COPD) patients.
- Trial name
- NCT04236076
- Testing
- PulseHaler
- Volunteers
- 104 people
- Sponsor
- Respinova LTD
Healthy Volunteers, Pathologies for Which paCO2 Monitoring is Crucial, Particularly in the Context of Chronic Obstructive Pulmonary Disease (COPD)
Influence of Temperature on Transcutaneous Blood Gas Diffusion: CAPNOS Project
The measurement of tcpCO2 has many disadvantages: the need for regular calibration (4 to 8 hours) of the sensor, the fact that the sensor heats the skin (risk of burns), the impossibility of measurement in ambulatory and the high…
- Trial name
- CAPNOS (NCT05637138)
- Testing
- tcpCO2 measure, tcpO2 measure, measurement of tissue conductivity to CO2: KS
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease
Effectiveness of Acapella and ELTGOL Technique to Promote Airway Clearance in COPD:a Comparative Study
To compare the efficacy of acapella and expiration against open glottis (ELTGOL) technique in promoting airway clearance of chronic obstructive pulmonary disease (COPD) patients
- Trial name
- NCT02249455
- Testing
- Acapella, ELTGOL, conventional physiotherapy
- Where
- India
- Volunteers
- 30 people
- Sponsor
- PSG College of Physiotherapy
Chronic Obstructive Pulmonary Disease (COPD), Emphysema
The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort
This is an observational study examining outcomes and treatment patterns in a community-based cohort of subjects with Chronic obstructive pulmonary disease (COPD) who are based in the Kannapolis, NC area.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Chronic Bronchitis
- Trial name
- NCT02838108
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Duke University
COPD
Detection of Early Airway Obstruction in Patients With COPD Using RCexp
We hypothesize that Cexp during tidal and forced exhalation implemented to the routine spirometer may detect airway obstruction earlier than conventional spirometric indices such as FEV1 and FEV1/FVC.
- Trial name
- COPD TiCON (NCT06456047)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- East Slovak Institute for Cardiovascular Diseases
COPD
Effectiveness of Harmonica Playing in Improving Lung Function Among COPD Patients
Although it has been documented that harmonica playing plays a role in the pulmonary rehabilitation (PR) of patients with chronic obstructive pulmonary disease (COPD), current studies are limited by small sample sizes…
- Trial name
- NCT05995847
- Testing
- Harmonica playing program plus basic PR care with routine follow-up, Basic PR care with routine follow-up
- Where
- 2 sites in China
- Volunteers
- 248 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Critical Illness, Chronic Obstructive Lung Disease
Advance Care Planning Evaluation in Hospitalized Elderly Patients
The purpose of the study is to inform decision-makers of the best strategies to implement advanced care planning (ACP). An advanced care plan (ACP) is a verbal or written instruction describing what kind of care an individual…
- Conditions
- Critical Illness, Chronic Obstructive Lung Disease, Congestive Heart Failure, Cirrhosis
- Trial name
- ACCEPT (NCT01362855)
- Where
- 9 sites in Canada
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Daren K. Heyland
Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD)
The Effect of Neuromuscular Electrical Stimulation
The effect of neuromuscular electrical stimulation on muscle atrophy in sedated patients on intensive care was studied. The aim of this study was to explore if electrical stimulation could prevent muscle atrophy.
- Conditions
- Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD), Ventilatory Failure
- Trial name
- NCT00442728
- Testing
- ELECTRICAL STIMULATION
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Provinciale Hogeschool Limburg
Gingivitis; Chronic, Oxidative Stress
Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases.
- Conditions
- Gingivitis; Chronic, Oxidative Stress, Inflammation
- Trial name
- NCT05861206
- Testing
- GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse), CHX-MW group (0.12% CHX, as a positive control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yağmur Saraç Gül
Chronic Obstructive Pulmonary Disease (COPD)
Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Exercise Performance
The purpose of this study is to investigate the effect of nocturnal oxygen therapy during a stay at moderate altitude on exercise performance of patients with chronic obstructive lung disease.
- Trial name
- NCT02143609
- Testing
- oxygen
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University of Zurich
COPD (Chronic Obstructive Pulmonary Disease), COPD
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
This study aims to see if a co-designed balance training programme called Sport4Steadiness (S4S), is acceptable to people with COPD and if the study procedures, including recruitment and the collection of outcomes, is feasible.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Balance Exercise, Falls, Intervention
- Trial name
- B-PuRe (NCT07750821)
- Testing
- Sport4Steadiness
- Where
- 3 sites in United Kingdom
- Volunteers
- 77 people
- Sponsor
- Samantha Harrison
Chronic Obstructive Pulmonary Disease, Non Invasive Ventilation
Interfaces of Non-invasive Ventilation on Performance in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine wether the interface (facial or nasal mask) influences performance in patients with chronic obstructive pulmonary disease exercising with non-invasive ventilation.
- Conditions
- Chronic Obstructive Pulmonary Disease, Non Invasive Ventilation, Exercise, Aerobic
- Trial name
- Exercise-NIV (NCT02796599)
- Testing
- Non invasive ventilation during exercise with facial or nasal mask.
- Where
- France
- Volunteers
- 21 people
- Sponsor
- ADIR Association
Coccygodynia, Coccydynia
Comparison of Ganglion Impar Radiofrequency Ablation and Phenol Neurolysis Techniques for Chronic Coccydynia Treatment
Radiofrequency ablation and phenol neurolysis of the ganglion impar are methods used in cases unresponsive to medication, particularly in patients who derive short-term or partial relief from the initial ganglion impar block.
- Trial name
- NCT07021365
- Testing
- Phenol Injection, Radiofrequency ablation alone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
COPD, Copd Bronchitis
Muco-ciliary Cleansing of Lungs in COPD With and Without a Salt Particle Inhaler
Cross-over trial of the effect of a salt particle inhaler on pulmonary muco-ciliary cleansing in COPD patients as measured by lung scintigraphy.
- Trial name
- NCT03927365
- Testing
- Inhalation from a salt particle inhaler with or without content
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Liita Care ApS
COPD Chronic Obstructive Pulmonary Disease
Digital Follow-up Program for People with Chronic Obstructive Pulmonary Disease in Primary Healthcare
Chronic Obstructive Pulmonary Disease (COPD), characterized by non-reversible airflow obstruction, contributes to high mortality and morbidity rates worldwide, including Norway.
- Trial name
- NCT06401512
- Testing
- Guided self-determination (GSD) follow-up approach by primary care nurses.
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Western Norway University of Applied Sciences
Emphysema, COPD
Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT)
This is a prospective, open-label, multi-center, single-arm study to be conducted at up to 20 investigational sites. The Study plans to enroll up to 140 subjects with severe emphysema and collateral ventilation in the target…
- Conditions
- Emphysema, COPD, Severe Emphysema
- Trial name
- CONVERT (NCT04559464)
- Testing
- AeriSeal, Zephyr Valves
- Where
- 14 sites in Australia, France and 5 more
- Volunteers
- 102 people
- Sponsor
- Pulmonx Corporation
Chronic Obstructive Pulmonary Disease
Smartphone-based Self-management in COPD Patients: A Needs Assessment Survey
COPD patients often experience multiple symptoms (e.g. dyspnea, cough, and deteriorating quality of life) and have imposed a substantial economic and social burden on health care.
- Trial name
- NCT05151198
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease
Efficacy of Interval Aerobic Training Versus Laser Puncture Therapy on Restless Leg Syndrome in Copd Patient
DETERMINE HOW TO IMPROVE THE QUALITY OF LIFE FOR PATIENTS WITH COPD BY DECREASING TINTENSITY OF THE RESTLESS SYNDROME
- Trial name
- NCT06955000
- Testing
- traidmail, laser puncture therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Pharos University in Alexandria
Pulmonary Disease, Chronic Obstructive
Simvastatin Therapy for Moderate and Severe COPD
To determine the effect of daily administration of 40 mgms simvastatin taken for at least 12 months (range 12-36 months) on the frequency of exacerbations of chronic obstructive lung disease (COPD) in patients with moderate to…
- Trial name
- STATCOPE (NCT01061671)
- Testing
- simvastatin
- Where
- 51 sites in United States, Canada
- Volunteers
- 885 people
- Sponsor
- University of Minnesota
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