Clinical trials: Obstructive Jaundice
Gallstone Disease, Obstructive Jaundice
Remaxol® Used in the Treatment of Patients With Gallstone Disease Complicated With Obstructive Jaundice
Obstructive jaundice is observed in 10-80 % of gallstone disease cases. The conventional tactics for the management of patients with obstructive jaundice is to remove biliary hypertension by using endoscopic or minimally invasive…
- Trial name
- NCT05928286
- Testing
- Remaxol
- Where
- 9 sites in Russia
- Volunteers
- 286 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Obstructive Jaundice
Patients With Obstructive Jaundice In Sohag University Hospital
Study of patients with obstructive jaundice in Sohag university hospital study the clinical, laboratory and imaging charachteristics in patients with obstructive jaundice admitted to sohag university hospital, and to study the…
- Trial name
- Jaundice (NCT06456476)
- Testing
- ERCP
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Sohag University
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Obstructive Jaundice
Investigating the Efficacy and Safety of the Combination Treatment of Huaier Granule and Biliary Drainage for MOJ
This study is designed to evaluate the efficacy and safety of the combination treatment of Huaier granule and biliary drainage for malignant obstructive jaundice.
- Trial name
- NCT03491254
- Volunteers
- 852 people
- Sponsor
- zhaoyu liu
Jaundice, Obstructive
Endoscopic Access Loop With Bilio-enteric Anastomosis: A Prospective Randomized Comparison Between Gastric and Subcutaneous Accesses
Roux-en-Y hepaticojejunostomy is the standard procedure used by most hepatobiliary surgeons for biliary reconstruction following iatrogenic bile duct injury, benign and malignant CBD strictures, choledochal cysts and biliary…
- Trial name
- NCT03252379
- Testing
- hepaticojejunostomy, modified hepaticojejunostomy with subcutaneous access loop, modified hepaticojejunostomy with gastric access loop
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bile Duct Neoplasm, Obstructive Jaundice
Comparison Between Two Methods of Bilateral Stenting for Malignant Hilar Obstruction
Internal biliary drainage using stent is used for malignant hilar obstruction such as cholangiocarcinoma, hepatocellular carcinoma and other malignancy including metastasis.
- Trial name
- NCT01622803
- Testing
- parallel stent, Y-stent (BONASTENT M-Hilar)
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Obstructive Jaundice
Endoscopic Retrograde Cholangiopancreatography In Patients Older Than 65Years Old With Obstructive Jaundice: Efficacy And Outcome
The incidence of pancreato-biliary disorders ,including malignancy, is increasing in elderly patients. Endoscopic retrograde cholangiopancreatography (ERCP) is a well-known therapeutic tool for these pancreato-biliary disorders.
- Trial name
- NCT06093048
- Testing
- Endoscopic retrograde cholangiopancreatography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Obstructive Jaundice, Disease as Reason for ERCP
Immune Function in Patients With Obstructive Jaundice
Patients with obstructive jaundice (OJ) often require surgical, endoscopic or radiological interventions to facilitate biliary drainage and relieve jaundice.
- Conditions
- Obstructive Jaundice, Disease as Reason for ERCP, Immune Dysfunction, Immune Tolerance
- Trial name
- NCT01367821
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Jaundice, Obstructive
Remaxol® in Mechanical Jaundice of Non-malignant Origin
The purpose of this study is to assess the safety and efficacy of Remaxol (succinate + methionine + inosine + nicotinamide; POLYSAN Ltd., Russia) infusions at dose 400 and 800 ml to treat mechanical jaundice of non-tumor cause…
- Trial name
- NCT03418935
- Testing
- Remaxol (succinate + methionine + inosine + nicotinamide), Ringer's Solution
- Where
- 13 sites in Russia
- Volunteers
- 342 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis
Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids
This study evaluates corticosteroids in the treatment of obstructive jaundice in autoimmune pancreatitis and/or immunoglobulin G4 (IgG4)-related sclerosing cholangitis in adults.
- Conditions
- Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis, Obstructive Jaundice
- Trial name
- NCT02797665
- Testing
- corticosteroids, biliary stent
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Jaundice
Effect of Methylene Blue on Perioperative Organ Function in Patients With Obstructive Jaundice
Increased production of vasodilating substances such as NO plays an important role in the development of vasoplegic syndrome caused by obstructive jaundice.Methylene blue plays a role in raising blood pressure by inhibiting the…
- Trial name
- NCT04109859
- Testing
- Saline, Methylene Blue
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Jiaolin Ning,MD
Malignant Obstructive Jaundice
Comparison of Two Seed Strand Implantation Techniques for Biliary Cancer
This study aimed to compare the safety and effectiveness of two different methods for fabricating and implanting Iodine-125 (^125^I) radioactive seed strands combined with a metal stent for treating malignant obstructive…
- Trial name
- NCT07381439
- Testing
- Percutaneous transhepatic biliary stenting with conventional linear ^125^I seeds strand, Percutaneous transhepatic biliary stenting with novel spiral ^125^I seeds strand
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for the diagnosis and treatment of pancreatobiliary diseases.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07637721
- Testing
- The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula
- Where
- 3 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University
Obstructive Jaundice, Pancreatic Cancer
Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression
Covered self expandable metal stents (CSEMS) are three times larger in diameter than 10 Fr plastic stents. When compared to plastic stents, randomized trials have shown longer patency and fewer stent-related complications for…
- Trial name
- NCT01191814
- Testing
- Metal stent, Plastic stent
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- AdventHealth
Jaundice, Obstructive, Cholangiopancreatography, Endoscopic Retrograde
A RCT of Low MBO Drainage Strategies
The purpose of this study is to evaluate the efficacy and safety of EUS-BD compared with ERCP-BD in low biliary obstruction caused by periampullary cancer, pancreatic cancer or low bile duct cancer.
- Conditions
- Jaundice, Obstructive, Cholangiopancreatography, Endoscopic Retrograde, Endoscopic Ultrasound-Guided Drainage
- Trial name
- NCT06196164
- Testing
- EUS-BD, ERCP-BD
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Pancreas Cancer, Cholangiocarcinoma
Radiofrequency Ablation for Biliopancreatic Malignancy
This phase-2 study aims to evaluate feasibility, safety and efficacy of thermal ablation of biliary obstructive malignancies by means of radiofrequency ablation (RFA, ELRA, StarMed) during endoscopic retrograde…
- Conditions
- Pancreas Cancer, Cholangiocarcinoma, Obstructive Jaundice
- Trial name
- IGNITE-1 (NCT02468076)
- Testing
- Radiofrequency ablation (StarMed)
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) with propofol.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07012772
- Testing
- The COMBO Endoscopy Oropharyngeal Airway
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Obstructive Jaundice, Biliary Stricture
Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis
The use of an endoprothesis in a pancreatic duct is a measure to minimize the incidence and severity of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis.
- Conditions
- Obstructive Jaundice, Biliary Stricture, Sphincter of Oddi Dysfunction
- Trial name
- ARCHIMEDE (NCT03977779)
- Testing
- Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Institut Paoli-Calmettes
Obstructive Jaundice
Pre-treatment With Methylene Blue Prevent Peri-operative Reduced Systemic Vascular Resistance
To explore the effects of pre-treatment with methylene blue on reduced perioperative vascular resistance in patients with obstructive jaundice.
- Trial name
- NCT03406676
- Testing
- Methylene Blue
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- Southwest Hospital, China
Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer
Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD).
- Conditions
- Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT01134276
- Testing
- biliary drainage
- Where
- South Korea
- Volunteers
- 211 people
- Sponsor
- Seoul National University Hospital