Clinical trials: Obstructive Lung Disease
Asthma
Study Of RV-39 In Patients Who Also Have Asthma
This study will last up to 9 weeks. Subjects will visit the clinic up to 14 times. Certain clinic visits will include a physical examination, lung function tests, inflammatory cell analysis from nasal secretions and/or sputum…
- Trial name
- NCT00503009
- Testing
- fluticasone propionate/salmeterol, fluticasone propionate
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
Asthma, Rhinitis
Screening Scottish Swimmers for Asthma and Rhinitis
The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.
- Trial name
- CLE004 (NCT00831428)
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 97 people
- Sponsor
- Brian J Lipworth
Chronic Graft Versus Host Disease
Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)
The primary objective of this study is to evaluate the effect of entospletinib (ENTO) on the best overall response rate in adults with chronic graft versus host disease (cGVHD) who are currently receiving systemic corticosteroids…
- Trial name
- NCT02701634
- Testing
- ENTO
- Where
- 30 sites in United States, Canada and 5 more
- Volunteers
- 66 people
- Sponsor
- Gilead Sciences
Asthma
A Safety Extension Study With Benralizumab for Asthmatic Adults on Inhaled Corticosteroid Plus Long-acting β2 Agonist
The purpose of this study is to continue to characterize the safety profile of benralizumab administration and monitor the pharmacodynamic activity of the drug in those asthma patients who remain on treatment for at least 16…
- Trial name
- MELTEMI (NCT02808819)
- Testing
- Benralizumab
- Where
- 178 sites in United States, Argentina and 13 more
- Volunteers
- 447 people
- Sponsor
- AstraZeneca
Chronic Graft-versus-host-disease
A Study of Itacitinib for the Treatment of Chronic Graft Versus Host Disease (cGVHD)
This study is being done in patients who have been receiving corticosteroids or other immunosuppressive therapies for the treatment of cGVHD for at least 6 months.
- Trial name
- NCT04200365
- Testing
- Itacitinib
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- SCRI Development Innovations, LLC
Pulmonary Disease, Chronic Obstructive
Assessment of Chronic Obstructive Pulmonary Disease (COPD) Therapy From the Physicians Perspective Using Tiotropium as an Example
Documentation of successful therapy with tiotropium (Spiriva Respimat; Spiriva (tiotropium 18 mcg capsules)) in COPD patients requiring long-acting bronchodilators: description of the most important outcome parameters according…
- Trial name
- NCT01036763
- Where
- 352 sites in Germany
- Sponsor
- Boehringer Ingelheim
Asthma
Study HZA106827: Efficacy/Safety Study of Fluticasone Furoate/Vilanterol (GW642444) in Adult and Adolescent Asthmatics
The purpose of the study is to compare the efficacy and safety of fluticasone furoate/vilanterol (GW642444) inhalation powder and fluticasone furoate inhalation powder both administered once daily in adolescent and adult subjects…
- Trial name
- NCT01165138
- Testing
- Fluticasone furoate/Vilanterol Inhalation Powder, Fluticasone Furoate Inhalation Powder
- Where
- 70 sites in United States, Germany and 4 more
- Volunteers
- 612 people
- Sponsor
- GlaxoSmithKline
Asthma
Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation.
- Trial name
- NCT01219738
- Testing
- Budesonide 360ug, Budesonide 720ug, Budesonide 1440ug
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
COPD
A Randomized, Multicenter, Open-label, Parallel-group, 12-week Study to Assess the Efficacy and Safety of Switching From Tiotropium to QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) in Symptomatic Mild to Moderate COPD Patients
To demonstrate superiority of QVA149 (110/50 μg) once daily compared to tiotropium 18 μg once daily in terms of trough forced expiratory volume in 1 second (FEV1) (mean of 45 min and 15 min pre-dose) following 12 weeks of…
- Trial name
- NCT02566031
- Testing
- Indacaterol and glycopyrronium (QVA149), Tiotropium
- Where
- 24 sites in South Korea
- Volunteers
- 379 people
- Sponsor
- Novartis Pharmaceuticals
Uncontrolled Asthma, Young Adults
Medication Adherence With Telehealthcare Medication Therapy Management
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an…
- Trial name
- MATCH (NCT03978936)
- Testing
- Medication Therapy Management (MTM) Video Telehealthcare, Electronic Adherence Self-Management (EAM)
- Where
- 21 sites in United States
- Volunteers
- 375 people
- Sponsor
- Johns Hopkins University
Migraine
Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients
The purpose of this study was to evaluate the efficacy and safety of erenumab in patients with chronic migraine in Asian population.
- Trial name
- DRAGON (NCT03867201)
- Testing
- Erenumab
- Where
- 63 sites in China, India and 7 more
- Volunteers
- 557 people
- Sponsor
- Novartis Pharmaceuticals
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
IVR-Enhanced Care Transition Support for Complex Patients
For complex medical patients, the transition from hospital to home-based care is a vulnerable period, placing the patient at high risk for adverse events.
- Trial name
- NCT01135381
- Testing
- IVR-Enhanced Care
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- University of Alabama at Birmingham
Asthma
Efficacy and Safety of Different Doses of Indacaterol
This study compared the 14-day bronchodilator efficacy of indacaterol with that of placebo and salmeterol
- Trial name
- NCT01079130
- Testing
- Indacaterol, Salmeterol
- Where
- 71 sites in United States
- Volunteers
- 511 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
A Study of 2 Doses of MAP0010 and Placebo in Asthmatic Children
The purpose of this study is to examine the safety and efficacy of two doses of MAP0010 versus placebo in asthmatic infants and children, 12 months to 8 years of age, over a 12-week treatment period.
- Trial name
- NCT00569192
- Testing
- 0.135mg MAP0010, 0.25mg MAP0010
- Volunteers
- 360 people
- Sponsor
- Allergan
Chronic Obstructive Pulmonary Disease (COPD)
A Multi-centre Randomized Double Blind 52-week Study to Assess the Safety of QVA149 Compared to QAB149 in Patients With COPD Who Have Moderate to Severe Airflow Limitation
This study is to assess the safety and tolerability of two different doses of QVA149 and QAB149 in patients with moderate to severe airflow limitation.
- Trial name
- NCT01682863
- Testing
- QVA149, QAB149
- Where
- 86 sites in United States, Bulgaria and 5 more
- Volunteers
- 614 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD), Chronic Bronchitis
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis
This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult participants with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis.
- Trial name
- FRONTIER-4 (NCT04631016)
- Testing
- Tozorakimab
- Where
- 90 sites in United States, Australia and 13 more
- Volunteers
- 137 people
- Sponsor
- AstraZeneca
Central Serous Chorioretinopathy
Eplerenone for the Treatment of Central Serous Chorioretinopathy
To test the effect oral eplerenone versus placebo in patients with central serious chorioretinopathy .
- Trial name
- NCT01990677
- Testing
- 25mg Eplerenone
- Where
- 10 sites in United States
- Volunteers
- 108 people
- Sponsor
- Wills Eye
Asthma
Assessment of the Safety and Efficacy of Dupilumab in Children With Asthma (Liberty Asthma Excursion)
Primary Objective: To evaluate the long-term safety and tolerability of dupilumab in pediatric patients with asthma who participated in a previous dupilumab asthma clinical study.
- Trial name
- NCT03560466
- Testing
- Dupilumab (SAR231893/REGN668), Asthma controller therapies (incl. prednisone/prednisolone), Asthma reliever therapies
- Where
- 81 sites in United States, Argentina and 16 more
- Volunteers
- 378 people
- Sponsor
- Sanofi
Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic
Effect of BIBW 2948 BS in COPD
Study of BIBW 2948 BS in Patients with COPD and Chronic Bronchitis
- Trial name
- NCT00423137
- Testing
- BIBW 2948 BS
- Where
- 6 sites in United States, Germany
- Volunteers
- 48 people
- Sponsor
- Boehringer Ingelheim
Asthma
Clinical Trial to Assess Efficacy, Safety, Treatment Adherence and Quality of Life Impact of Mometasone Furoate in Asthmatic Patients (Study P04879)(TERMINATED)
Open label, 12-week clinical trial to assess efficacy, safety, treatment adherence and Quality of Life impact of Mometasone Furoate dry powder 400 mcg once-daily in persistent mild-moderate asthmatic patients at least 12 years…
- Trial name
- APEGO (NCT00687531)
- Testing
- Mometasone Furoate
- Volunteers
- 385 people
- Sponsor
- Organon and Co
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.