Clinical trials: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Obstructive Sleep Apnea
Improving 24-hour Blood Pressure in Obstructive Sleep Apnea
This study examines the combined effects of an angiotensin receptor blocker (ARB), antioxidant supplementation, and continuous positive airway pressure (CPAP) therapy on the lowering of 24-hour blood pressure in persons with…
- Trial name
- NCT04021550
- Testing
- Continuous Positive Airway Pressure CPAP, Telmisartan 80mg, Alpha-Lipoic Acid 600mg
- Sponsor
- University of British Columbia
Retinal Vein Occlusion, Obstructive Sleep Apnea
Retinal Vein Occlusion and Obstructive Sleep Apnea: A Case Control Study
This study purpose is to evaluate the association between Retinal Vein Occlusion and Obstructive Sleep Apnea.
- Trial name
- SASOVR (NCT04011358)
- Testing
- Sleeping Monitor
- Where
- France
- Sponsor
- Centre Hospitalier Régional d'Orléans
Sleep Apnea, Obstructive
Effect of AD128 to Treat Obstructive Sleep Apnea
This study evaluates the combination of two drugs (AD128), to treat obstructive sleep apnea (OSA) severity. After a baseline evaluation and during 7 days, half of the participants will randomly receive this drug combination…
- Trial name
- NCT04394143
- Testing
- AD128, Mannitol
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Raphael Heinzer
Obstructive Sleep Apnea
Biomarkers in Obstructive Sleep Apnea Surgery
Recent years have witnessed major advances in the understanding of the hormonal, metabolic, and biochemical changes that occur in obstructive sleep apnea (OSA).
- Trial name
- NCT00507078
- Testing
- Surgical treatment for OSA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Sleep Apnea, Obstructive, Apnea, Sleep
Study Using Negative Pressure to Reduce Apnea
The objective of this study is to determine the safety and effectiveness of the aerSleep® II device for treatment of moderate to severe Obstructive Sleep Apnea (OSA) over 24 weeks of home use in spontaneously breathing adult…
- Trial name
- SUPRA (NCT04861038)
- Testing
- aerSleep II
- Where
- 15 sites in United States
- Volunteers
- 900 people
- Sponsor
- Sommetrics, Inc.
Sleep Apnea, Obstructive
The Endothelium Dysfunction in Patients of Obstructive Sleep Apnea Syndrome
study Hypothesis: We hypothesize that CPAP could effectively improve the endothelial dysfunction by anti-inflammatory effect in patients of OSA,and compare to the effect of statin.
- Trial name
- NCT01699126
- Testing
- CPAP, Statin
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea, Refractory Hypertension
Effects of Continuous Positive Airway Pressure (CPAP) in Patients With Resistant Hypertension and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is an important cause of refractory hypertension but the impact of treatment with continuous positive airway pressure (CPAP) is not completely understood.
- Trial name
- NCT00812695
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Obstructive Sleep Apnea Syndrome, Brain Infarction
Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke.
Obstructive Sleep Apnea Syndrome (OSAS) is associated with stroke as a risk factor but little is known about the consequences of OSAS on the outcome and the survival after stroke.
- Trial name
- NCT01561677
- Testing
- Continuous Positive Airway pressure-RESPIRONICS
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea
The Effect of Occlusal Splints on Respiratory Variables in Obstructive Sleep Apnea (OSA) Patients
Rationale: The effect of vertical dimension on sleep apnoea and respiratory variables in obstructive sleep apnoea patients. Objective: To what extend should a possible worsening of the OSA condition, caused by an increase of…
- Trial name
- NCT01004692
- Testing
- Occlusal splints
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Obstructive Sleep Apnea
Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients
The purpose of this study is to test whether Spironolactone can improve the severity of obstructive sleep apnea and improve cardiovascular biomarkers in people who are not regularly using their Positive Airway Pressure (PAP)…
- Trial name
- NCT04205136
- Testing
- Spironolactone
- Where
- United States
- Sponsor
- University of Michigan
Obstructive Sleep Apnea
The Treatment of Obstructive Sleep Apnea With Continuous Positive Airway Pressure on Appearance and Age
The investigators hypothesized that the treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) will positively affect the appearance of the patient.
- Trial name
- NCT02117271
- Testing
- continuous positive airway pressure, Breathe Right ®
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo Interdisciplinar da Ciencia do Sono
Obstructive Sleep Apnea Syndrome
Predictive Value of Induced Sleep Endoscopy on Surgical Indication in Obstructive Sleep Apnea Syndromes
Obstructive sleep apnea syndrome (OSA) is a pathology that affects 2 to 15% of the French adult population and more than 30% of subjects over 65 years old.
- Trial name
- SOMMEIL_INDUIT (NCT05201222)
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Sleep Apnea
Effects of Upper Airway Muscle Training on Obstructive Sleep Apnea Severity
The purpose of this study is to evaluate the effect of Asate Silent Sleep Training on obstructive sleep apnea (OSA) severity in patients with mild to moderate OSA.
- Trial name
- NCT04053153
- Testing
- Exercise equipment (a musical instrument that is based on the Medical Didgeridoo)
- Sponsor
- Stanford University
Obstructive Sleep Apnea Syndrome
VASO-AM :Impact of Oral Appliance Therapy on Endothelial Function in Obstructive Sleep Apnea
This is a randomized controlled study evaluating the impact of 2 months of oral appliance therapy on endothelial function in patients with severe obstructive sleep apnea syndrome intolerant to continuous positive airway pressure…
- Trial name
- VASO-AM (NCT01426607)
- Testing
- AMO
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Dyslipidemias
CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea
Clinical Trial Phase IV Indication: Moderate-severe obstructive sleep apnea and dyslipidemia. Objectives: Main objective: To test whether 12 months of CPAP treatment associated with conventional pharmacological treatment improves…
- Conditions
- Sleep Apnea, Dyslipidemias, Hyperuricemia
- Trial name
- CPAPLIP (NCT06463561)
- Testing
- Continuous positive airway pressure, Hygienic-dietary recommendations and daily physical activity promotion
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Hospital Universitario La Paz
Diabetic Complications and Obstructive Sleep Apnea
Diabetic Complications and Obstructive Sleep Apnea
To follow up the progress of chronic complications in T2DM patients who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018.
- Trial name
- DMOS (NCT04646941)
- Testing
- regular treatment
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Obstructive Sleep Apnea, End Stage Renal Disease
Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients
The purpose of this study is to prospectively evaluate the impact of sleep apnea on the cardiovascular morbidity and mortality of patients with end-stage renal disease.
- Trial name
- SASinHD_003 (NCT02073305)
- Testing
- No Sleep Apnea, Sleep Apnea - untreated, Sleep Apnea - treated
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obstructive Sleep Apnea, Hypertension
Antihypertensive and PAP Treatment in Obstructive Sleep Apnea Patients With Hypertension (AHPAP)
The investigators will perform a long term registry based prospective analysis on incidence of major cardiovascular events or death in hypertensive patients with obstructive sleep apnea .
- Conditions
- Obstructive Sleep Apnea, Hypertension, Death, Cardiac, Treatment Compliance
- Trial name
- AHPAP (NCT05115994)
- Testing
- Continous positive airway pressure
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Vastra Gotaland Region
Adenotonsillectomy
Adenotonsillectomy and Obstructive Sleep Apnea Study
Adenotonsillectomies are one of the most common childhood surgeries and are first-line treatment to correct childhood obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT01462539
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Nationwide Children's Hospital
Obstructive Sleep Apnea Syndrome
Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea
The purpose of this study is to determine the effectiveness and feasibility of upper airway muscle physical therapy utilizing negative airway pressure (NAP) breathing training in patients with Obstructive Sleep Apnea Syndrome…
- Trial name
- NCT02109731
- Testing
- Negative airway pressure delivery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
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