Clinical trials: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Obstructive Sleep Apnea
TURKAPNE - The Turkish Sleep Apnea Database: A National, Multicenter, Observational, Prospective Cohort Study
Primary aim of the TURKAPNE (The Turkish Sleep Apnea Database) study is to generate a cross-sectional nationwide database to define clinical and polysomnographic characteristics of the sleep apnea patients in Turkey.
- Trial name
- TURKAPNE (NCT02784977)
- Testing
- Positive Airway Pressure (PAP), Intraoral device (IOD), Uvuloplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Koç University
Sleep Apnea, Obstructive
Postoperative Oral Cryotherapy in Sore Throat and Daily Life
The purpose of this study will to evaluate the degree of postoperative sore throat and Life Impairment changes in patients with sleep apnea who underwent da Vinci robotic arm surgery as an intervention of oral cryotherapy.
- Trial name
- NCT06249295
- Testing
- oral cryotherapy
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Obstructive Sleep Disorder, Obstructive Sleep Apnea
Topical Microporous Polysaccharide Hemospheres Versus Electrocautery for Control of Pediatric Post-Tonsillectomy Bleeding
The ultimate goal of this work is to establish a method for control bleeding after tonsillectomy in awake children. Treatment of post-tonsillectomy bleeding in children typically requires general anesthesia with currently used…
- Conditions
- Obstructive Sleep Disorder, Obstructive Sleep Apnea, Tonsillar Hypertrophy
- Trial name
- NCT00945412
- Testing
- Micropolysaccharide Hemospheres (Arista), Electrocautery (Monopolar suction cautery)
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary
Sleep Apnea, Obstructive
Evaluation of Self-efficacy as a Predictor for CPAP-compliance in a OSAS-patients French Cohort
Continuous positive airway pressure (CPAP) is the reference treatment for obstructive sleep apnea syndrome (OSAS) and is effective in improving symptoms of OSAS, reducing risk of accidents and improving quality of life.
- Trial name
- SAFES (NCT05053581)
- Testing
- Survey
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Obstructive Sleep Apnea
The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea
The investigators hypothesis is that obstructive sleep apnea (OSA) patients with a low arousal threshold may wake up too early during a respiratory event, before upper airway muscles can be activated to achieve stable…
- Trial name
- NCT02714400
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Childhood Obesity, Childhood Obstructive Sleep Apnea
Co-existent Obstructive Sleep Apnea (OSA) and Obesity: Finding Non-exercise Activity Thermogenesis (NEAT) Targets for Intervention
Rationale: Obesity is an increasing childhood epidemic in Canada. Obstructive sleep apnea (OSA) is a complication of obesity which causes cardiovascular disease, reduced quality of life, and premature death.
- Trial name
- NCT00854334
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Katz, Sherri Lynne, M.D.
Sleep Apnea, Obstructive
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with obstructive sleep…
- Trial name
- NCT00107809
- Testing
- Modafinil
- Where
- 64 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon
Obstructive Sleep Apnea of Adult
Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
The goal of this clinical trial is to learn if melatonin works to treat comorbid insomnia in adults with OSA and nocturnal non-dipping blood pressure pattern.
- Trial name
- MEBP-OSA (NCT06380491)
- Testing
- Melatonin 3 MG Oral Tablet
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Sleep Disordered Breathing, Obstructive Sleep Apnea
Sleep Disordered Breathing and Gestational Hypertension
Sleep disordered breathing (SDB) is a common problem in the adult population. By conservative estimates, 4% of the adult female population has SDB.
- Conditions
- Sleep Disordered Breathing, Obstructive Sleep Apnea, Gestational Hypertension, Preeclampsia
- Trial name
- NCT00757718
- Testing
- CPAP, Oral Appliance
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Saskatchewan
Down Syndrome, Obstructive Sleep Apnea
Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
This study aims to see if mobile video clips (smartphone recordings) can be used to screen children with Down syndrome to identify those at highest risk of obstructive sleep apnea (OSA), so they can be prioritized for an earlier…
- Conditions
- Down Syndrome, Obstructive Sleep Apnea, Child
- Trial name
- UPLOAD (NCT04022460)
- Testing
- Video clip assessment, Polysomnography (sleep study), Educational webinar
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- Children's Hospital of Eastern Ontario
Endothelial Dysfunction
Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome
Evaluation of miRNA contained in exosomes in obese and OSA patients with endothelial dysfunction evaluated by digital plethysmography (ENDOPAT) compared to obese and OSA patients without endothelial dysfunction.
- Trial name
- EXODYS (NCT04459182)
- Testing
- ENDOPAT
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Angers
Obstructive Sleep Apnea, Acute Kidney Failure
Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function
Obstructive sleep apnea (OSA) is a frequently underdiagnosed condition that has emerged as an increasing medical problem with important social and financial implications worldwide.
- Conditions
- Obstructive Sleep Apnea, Acute Kidney Failure, Chronic Kidney Disease
- Trial name
- OSA-AKI (NCT00947479)
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
The aim of this study is to evaluate whether a smaller dose of caffeine sodium benzoate 10 mg/kg IV is as effective as 20 mg/kg IV in decreasing the number of children who develop post extubation adverse upper airway respiratory…
- Trial name
- NCT01349205
- Testing
- Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obstructive Sleep Apnea, Muscle Disorder
Effects of Newly-created Individualized Upper Airway Muscle Functional Training on Patients With OSA
Objectives: To observe the effect of newly-created individualized upper airway muscle functional training on the condition and intraday symptoms of OSA patients; to study the effect of this training method on the excitability of…
- Trial name
- NCT05346705
- Testing
- New individualized upper airway muscle functional training
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Hospital of China Medical University
Sleep Apnea, Obstructive
Comparison of Preoperative Screening Score for Obstructive Sleep Apnea (OSA)
Comparison of preoperative screening score for OSA. In a preoperative population, comparison of the STOP-BANG, DES-OSA, P-SAP and OSA50 score.
- Trial name
- NCT02051829
- Testing
- Comparison of the four screening score
- Where
- Belgium
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Astes
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Validation and Reproducibility of the Six-minute Step Test in Individuals With Obstructive Sleep Apnea Treated With CPAP
Introduction: The Obstructive Sleep Apnea (OSA) is characterized by obstructed superior airway during sleeping period promoting intermittent hypoxia-reoxygenation events.
- Trial name
- NCT03334331
- Testing
- Six-minute step test, Six-minute walk test
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Obstructive Sleep Apnea
Change in C-reactive Protein (CRP) in Men and Women With Sleep Apnea After Continuous Positive Airway Pressure (CPAP)
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT01365832
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Greece
- Volunteers
- 436 people
- Sponsor
- University of Crete
OSA, Adherence, Patient
Adherence to CPAP in Patients With OSA. Ten Year Follow up
The management of OSA is aimed to improve symptoms and mitigate reduce other health consequences. Continuous Positive Airway Pressure (CPAP) is the recognized treatment for OSA, able to reverse the pathophysiology of OSA and…
- Conditions
- OSA, Adherence, Patient, CPAP
- Trial name
- NCT03644121
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Maugeri Foundation
Obstructive Sleep Apnea
Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
The purpose of this research is to compare the impact of motivational enhancement therapy (MET), delivered by culturally congruent community health care workers (CHWs) versus usual care patients with previously untreated…
- Trial name
- Champion (NCT06047353)
- Testing
- Motivational Enhancement Therapy, Positive Airway Pressure (PAP) therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
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