Clinical trials: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Obstructive Sleep Apnea
Determinants of Tooth Movement in Oral Appliance Treatment of OSA.
Obstructive sleep apnea (OSA) is a sleep related breathing disorder, affecting approximately 10% of adults. Mandibular advancement oral appliances (OAM) are an effective treatment for OSA, however, long term use has shown to lead…
- Trial name
- TACO (NCT03341130)
- Testing
- Mandibular Repositioning Splint, Mandibular Advancement Oral Appliance
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of British Columbia
Obstructive Sleep Apnea Syndrome
Screening of Obstructive Sleep Apnea Syndrome in Residents of a Unit of Long-term Care Under Mixed Food
Obstructive sleep apnea is a condition that affects 40% to 62% of the population aged over 60 years with major consequences especially on the cardiovascular system. This syndrome consists of a staff of the pharyngeal muscles.
- Trial name
- NCT02839499
- Testing
- RU sleeping®, autonomy scale (ADL and AGGIR), various activity scale (IADL)
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obstructive Sleep Apnea Syndromes
Interest of Treatment of Obstructive Sleep Apnea Syndrome by Constant CPAP and Auto CPAP
The investigators propose a multicentric controlled randomized trial whose goal is to evaluate the possibility of a prediction of the efficiency of APAP (automatic continuous positive airway pressure) and constant CPAP (constant…
- Trial name
- PREDIVARIUS (NCT02749812)
- Testing
- Constant Continuous Positive Airway Pressure, Automatic continuous Positive Airway Pressure
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Snoring, Sleep Apnea, Obstructive
Genioglossus Muscle Training for Snoring and Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) carries serious health consequences for patients. Evidence exists that some behavioral (e.g. exercise based) therapies may assist in lessening the severity of this disorder.
- Trial name
- NCT02834767
- Testing
- Genioglossis Strength Trainer
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Obstructive Sleep Apnea
Prolonged Overnight Oximetry in Obstructive Sleep Apnoea
This study is looking at the way in which patients with obstructive sleep apnoea (OSA) are diagnosed. The investigators current practice is to offer patients who are referred to the sleep centre with possible sleep apnoea a…
- Trial name
- PROXIMO (NCT04287751)
- Testing
- CheckMeO2 Oximeter
- Volunteers
- 200 people
- Sponsor
- Somerset NHS Foundation Trust
Snoring, OSA - Obstructive Sleep Apnea
Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).
This clinical investigation is a prospective, non-randomized, parallel-group clinical investigation conducted at two (2) investigative sites.
- Trial name
- NCT07613281
- Testing
- Palatal Implant System
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Serene Sleep, Inc.
Sleep Apnea
Obstructive Sleep Apnoea in Patients With Intermittent Claudication
The main aim of this study is to determine how common undiagnosed obstructive sleep apnoea is in individuals with intermittent claudication.
- Trial name
- WITH-SAS (NCT01801592)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease
The primary purpose of the study is to determine whether lemborexant increases the apnea hypopnea index (AHI) on Day 8 of treatment in adult and elderly participants (adults greater than or equal to [>=] 45 to less than [<] 65…
- Conditions
- Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
- Trial name
- NCT04647383
- Testing
- Lemborexant 10 mg
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- Eisai Inc.
Obstructive Sleep Apnea
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism.
- Trial name
- NCT06317701
- Testing
- Hypoglossal Nerve Stimulation (HGNS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obstructive Sleep Apnea, Vasovagal Syncope
Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms.
The goal of this prospective cohort study is to study patients referred for sleep study by in-lab polysomnography in the Jordan University Hospital and the Jordan Hospital or with an at-home sleep study kit.
- Conditions
- Obstructive Sleep Apnea, Vasovagal Syncope, Smoking, Acanthosis Nigricans
- Trial name
- VasOSA (NCT06331819)
- Testing
- In-lab polysomnography, Continuous positive airway pressure, Home sleep study device
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- Jordan Collaborating Cardiology Group
Obstructive Sleep Apnea, Sleep Apnea
North West London Pebble Pathway: Automated OSA Diagnosis
Patients with obstructive sleep apnoea (OSA) wait up to two years for a diagnostic test. Early diagnosis enables optimal treatment, mitigating risks including heart failure, lung disease, and stroke.
- Trial name
- PEBBLE (NCT06507228)
- Testing
- NWL PEBBLE STT
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Patrik Bachtiger
Obstructive Sleep Apnea Syndrome
Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children
The therapeutic management of Obstructive Sleep Apnoea Syndrome in children remains a debated subject, only otorhinolaryngology surgery (adenoidectomy) has been studied on a large scale.
- Trial name
- SASDICO (NCT05164211)
- Testing
- Didgeridoo
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Apnea
Mediterranean-type Diet for Older Adults With Obstructive Sleep Apnea
The majority of the elderly present with sleep apnea and mortality is significantly higher in this group. Sleep apnea runs the risk of developing diseases, especially hypertension and cardiovascular disease, while the…
- Trial name
- MedOOSA (NCT03514199)
- Testing
- Mediterranean-type diet, Low fat diet
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obstructive Sleep Apnea
Lifestyle Interventions for Seniors With Apnea
The overall goal of this study is to determine the efficacy of a lifestyle intervention, consisting of a weight loss diet and exercise on sleep apnea in older adults.
- Trial name
- NCT01422863
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea
Post-Operative Steroids After Sleep Surgery
The primary objective of this randomized, placebo-controlled, double-blind study will be to determine if postoperative steroids significantly improve subjects' pain compared to a placebo after undergoing sleep surgery.
- Trial name
- NCT06818981
- Testing
- 8mg dexamethasone
- Where
- United States
- Sponsor
- Medical University of South Carolina
Obstructive Sleep Apnea/Hypopnea Syndrome
Comparison of Vascular Risk in Patients Treated for Obstructive Sleep Apnea/Hypopnea Syndrome
a monocentric,non interventional, prospective study to compare cardiovascular risk in patients with Obstructive Sleep Apnea/Hypopnea Syndrome treated with Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement…
- Trial name
- SAHOSVAS (NCT05491967)
- Where
- France
- Volunteers
- 172 people
- Sponsor
- Centre Hospitalier de Valence
Obstructive Sleep Apnea
Therapeutic Efficiency of Mandibular Advancement Device Using Smartphone Sleep Applications and Pulse Oximeter
An observational clinical trial in a single centre. The objective of this study was to determine the efficacy of mandibular advancement device (MAD) therapy on snoring intensity, frequency, and oxygen desaturation periods in…
- Trial name
- NCT04427111
- Testing
- Non-titratable-customized mandibular advancement device
- Volunteers
- 18 people
- Sponsor
- Bahadır EZMEK
Sleep Apnea
Prevention Of Delirium in Elderly With Obstructive Sleep Apnea (PODESA)
Delirium is a common complication in elderly patients following surgery. Patients who develop delirium after surgery are at increased risk for serious complications, and even death.This multi-centre randomized controlled trial…
- Trial name
- PODESA (NCT02954224)
- Testing
- CPAP treatment
- Where
- 3 sites in Canada
- Volunteers
- 220 people
- Sponsor
- University Health Network, Toronto
Narcolepsy, Obstructive Sleep Apnea
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life.
- Trial name
- PN-PROS (NCT05373979)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Boston Children's Hospital
Desaturation of Blood, Colonoscopy
The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal endoscopy with the patient under deep intravenous sedation.
- Trial name
- NCT03479905
- Testing
- Salter nasal cannula, Face mask, High Flow Nasal Cannula
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Texas Southwestern Medical Center
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