Clinical trials: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Obstructive Sleep Apnea
Can Objective Compliance Monitoring Increase Mandibular Advancement Device Usage in Obstructive Sleep Apnea Patients
This study evaluates whether objective compliance monitoring can increase mandibular advancement device (MAD) usage in obstructive sleep apnea (OSA) patients.
- Trial name
- NCT02885571
- Testing
- SomnoDent Flex with DentiTrac
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Osa Syndrome
Safety and Efficacy of Esmketamine Versus Dexmedetomidine
A comparative study on the safety and efficacy of esmketamine versus Dexmedetomidine during drug induced sleep endoscopy in children with positional obstructive sleep apnea: A consort-prospective, randomized, controlled clinical…
- Trial name
- NCT04877639
- Testing
- Esmketamine,Dexmedetomidine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Obstructive Sleep Apnea
The Effect of Melatonin on Sleep and Ventilatory Control in Obstructive Sleep Apnea
Our hypothesis is that oxidative stress induced during repeated apneas in obstructive sleep apnea (OSA) patients alters the neural control of breathing which destabilizes ventilatory control and exacerbates OSA.
- Trial name
- NCT02484300
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
OSA
Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases
The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as Overlap Syndrome (OS). The coexistence of these diseases have cardiovascular morbidity and mortality.
- Trial name
- NCT04903639
- Testing
- sleep study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Obstructive Sleep Apnea
CPAP Device In-lab Assessment NZ
The purpose of this trial is to assess device performance against participants in an overnight study to ensure the product meets user and clinical requirements
- Trial name
- NCT02948010
- Testing
- Auto CPAP + comfort feature A, Auto CPAP with comfort feature B, Auto CPAP with no comfort feature
- Where
- New Zealand
- Volunteers
- 104 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
SLEEP AND OSA ON REPRODUCTIVE FUNCTION IN MEN
In view of the hormonal changes induced by both sleep deprivation and obstructive sleep apnea syndrome (OSA), and the importance of maintaining these hormones in reproductive processes.
- Trial name
- PSAR01 (NCT01884454)
- Testing
- Sleep deprivation
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Obstructive Sleep Apnea
Side Effects of the Mandibular Advancement Device for Apnea Treatment on Dental Occlusion and Masticatory Function
This study evaluates the effect of the use of mandibular advancement devices (MAD) on dental occlusion and masticatory function during the first two years of obstructive sleep apnea (OSA) treatment.
- Trial name
- NCT05420129
- Testing
- MAD Therapy, CPAP Therapy
- Where
- Spain
- Sponsor
- University of Barcelona
Morbid Obesity, Metabolic Syndrome
Impact GLP-1 Agonists Following Bariatric
Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control hunger, induce satiety and plays a role in the metabolic…
- Conditions
- Morbid Obesity, Metabolic Syndrome, Diabetes Mellitus, Hypertension
- Trial name
- NCT06132477
- Testing
- GLP-1 receptor agonist
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Missouri-Columbia
Sleep Apnea
Portable System for Non-intrusive Monitoring of Sleep
Obstructive sleep apnea (OSA) is a prevalent kind of sleep-disordered breathing affecting one-seventh of the world's population. Almost 45 percent of this population suffers from mild to severe apnea.
- Trial name
- NCT06029881
- Testing
- Movesense MD
- Where
- Belgium
- Volunteers
- 47 people
- Sponsor
- Erasme University Hospital
Tonsillitis, Obstructive Sleep Apnea
Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy
This study was planned to compare vessel sealing system tonsillectomy (VSST) to the traditional cold knife tonsillectomy (CKT) with special regard to intraoperative bleeding, operative time, postoperative pain and hemorrhage.
- Trial name
- NCT00636402
- Testing
- Cold Knife Tonsillectomy, Vessel Sealing System Tonsillectomy
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea
High Flow Nasal Cannula for Obstructive Sleep Apnea
This study compare the efficacy of high flow nasal cannula with nasal continuous positive airway pressure. All of participants will be randomized to receive one night high flow nasal cannula therapy and another night for nasal…
- Trial name
- NCT03843372
- Testing
- High flow nasal cannula
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Chung-Chieh, Yu
Hypertension Arterial
Hypertension and Cardiovascular Risk Associated With Obstructive Sleep Apnea in Adult in Guadeloupe (French West Indies)
The MAPA is the reference method to estimate the PA during the SAHOS. The MAPA can be recommended over 48 hours: indeed, the PA falls at the beginning of every apnea then increases gradually up to a pressif peak arising at the…
- Trial name
- HTA-SAHOS (NCT03373357)
- Testing
- Patient not SAHOS, Patient SAHOS sailed by the ventilation in PPC and not sailed
- Where
- Guadeloupe
- Volunteers
- 220 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Sleep Apnea Syndromes
Screening of Sleep Apnea by Holter Electrocardiography: Validation of Heart Rate Variability Analysis Algorithm
Obstructive sleep apnea syndrome (OSAS) is a growing health concern affecting up to 60 % of population with cardiovascular disease.
- Trial name
- NCT05435001
- Testing
- Holter ECG Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Snoring, Obstructive Sleep Apnea Syndrome
Injection Snoreplasty and Oropharyngeal Exercises
A randomized single blind clinical trial, with a larger sample size than previous studies , to evaluate the effectiveness of injection snoreplasty in the treatment of patients with snoring and obstructive sleep apnea/hypopnea…
- Trial name
- NCT02568761
- Testing
- Injection Snoreplasty, Oropharyngeal Exercises
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obstructive Sleep Apnea
The Influences of Intervention With Home-based Recovery Activity in Obstructive Sleep Apnea Syndrome
Background: OSAS is a type of sleep disorder characterized by intermittent, partial or complete upper airway (UA) collapse, seriously impacting sleep apnea and respiratory insufficiency.
- Trial name
- OSAS (NCT02278094)
- Testing
- Tongue Muscle Trainer (TMT), Threshold Inspiratory Muscle Trainer (TIMT), Walking Exercise
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Cheng-Kung University Hospital
Obstructive Sleep Apnea of Adult
Dexmedetomidine Added to Propofol for Drug Induced Sleep Endoscopy
This study evaluate the effect of adding dexmedetomidine intravenous infusion to propofol intravenous infusion during sedation for drug induced sleep endoscopy.
- Trial name
- NCT03091894
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Essam Fathi
Obstructive Sleep, OSA
Hypoxic Burden and Sleepiness in Treated OSA Patients
The Maintenance of Wakefulness Test (MWT) is widely used to objectively assess sleepiness and make safety-related decisions and Epworth Sleepiness Scale (ESS) is the most used scale used to assess subjective sleepiness in sleep…
- Trial name
- MWTBH (NCT06700837)
- Testing
- Impact of hypoxic burden on objective and subjective sleepiness in patients treated for Obstructive Sleep apnea
- Where
- France
- Volunteers
- 141 people
- Sponsor
- Hospices Civils de Lyon
Obstructive Sleep Apnea
Evaluation of Obstructive Sleep Apnea (OSA) Using Portable Sleep Testing (PST) Devices on an Inpatient Stroke Unit
The purpose of this study is to evaluate the feasibility of testing patients for OSA within the inpatient setting. As part of this program, the investigators are proposing early access to a sleep apnea treatment plan, potentially…
- Trial name
- OSA (NCT06516354)
- Testing
- Portable sleep apnea screening
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Obstructive Sleep Apnea
The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices
Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of obstructive events (apnea and hypopnea) and intermittent hypoxia, which in turn contributes to the systemic inflammation that underlies this…
- Trial name
- NCT06265129
- Testing
- Complete blood picture (done in the morning after the night of monitored sleep by PSG. With stress on red blood cell indices (RBC count, MCV, MCH, RDW)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Severe Label Expansion for EVO Products Trial
Title: Severe Label Expansion for EVO Positioner (SLEEP) Study Description: Single-arm study to determine the safety and effectiveness of treating severe obstructive sleep apnea using the EVO Sleep and Snore Device (ProSomnus…
- Trial name
- SLEEP (NCT07090395)
- Testing
- EVO Sleep and Snore Device
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- ProSomnus Sleep Technologies
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