Clinical trials: Obstructive Sleep Apnea of Child
Obstructive Sleep Apnea
Effects of Positive Airway Pressure (PAP) in Children With Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea is a problem for a large number of children and can result in problems with thinking patterns, behaviors and sleep if left untreated.
- Trial name
- OSA (NCT01156649)
- Testing
- PAP therapy
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Tennessee
Sleep Apnea
Controlled Trial on Effect of Montelukast Treatment in Children With Obstructive Sleep Apnea Syndrome
Oral therapy with montelukast may lead to improved polysomnographic findings in children with mild to moderate OSAS with and without allergic rhinitis who a priori require T\&A for OSAS.
- Trial name
- NCT00599534
- Testing
- Montelukast
- Where
- 2 sites in United States
- Sponsor
- University of Louisville
Obstructive Sleep Apnea Syndrome
Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children
The therapeutic management of Obstructive Sleep Apnoea Syndrome in children remains a debated subject, only otorhinolaryngology surgery (adenoidectomy) has been studied on a large scale.
- Trial name
- SASDICO (NCT05164211)
- Testing
- Didgeridoo
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea Syndrome
Efficacy of Oral Leukotriene in Long Term Therapy of Mild and Moderate Obstructive Sleep Apnea Syndrome in Children
The aim of the project is to evaluate whether therapy with leukotriene may be a valid therapeutic approach in children with adenotonsillar hypertrophy and with mild and moderate obstructive sleep apnea syndrome (OSAS) and to…
- Trial name
- SB-OSAS (NCT00912171)
- Testing
- budesonide (Aircort 50 nasal spray), montelukast (Singulair)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Bologna
Narcolepsy, Sleep Apnea, Obstructive
PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or OSAHS (obstructive sleep…
- Trial name
- NCT00107848
- Testing
- Modafinil
- Where
- 61 sites in United States, Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Cephalon
Obstructive Sleep Apnea
Screening for Obstructive Sleep Apnea Syndrome in Children
To be able to diagnose obstructive sleep apnea syndrome (OSAS) in a patient, polysomnography (PSG) remains the gold standard. However, this is expensive, involves a considerable workload and is quite complex.
- Trial name
- NCT05896176
- Testing
- a clinical examination and anamnesis
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Tonsillitis, Obstructive Sleep Apnea of Child
Steroids and Pain Control After Tonsillectomy
This research study aims to find out if a single oral dose of steroid after tonsillectomy will reduce pain and decrease the need for narcotic medications.
- Trial name
- NCT03995628
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Medical University of South Carolina
Sleep Apnea, Obstructive, Sleep Disorder
Home Apnea Testing in CHildren Trial
This clinical trial will compare home sleep apnea testing with the gold standard in-lab polysomnography in terms of 1) accuracy, 2) therapeutic decision-making, and 3) parent/child acceptability in children referred for…
- Conditions
- Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
- Trial name
- HATCH (NCT05382754)
- Testing
- Home sleep apnea test, In-lab polysomnography
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Children's Hospital of Philadelphia
Sleep Apnea, Obstructive
Validation of ApneaLink Air Home Sleep Testing in the Diagnosis of Obstructive Sleep Apnea in Adolescent Children
The feasibility and the validity of the ApneaLink Air home sleep testing (HST) device will be tested in adolescent children. The ApneaLink Air HST device is cleared for the diagnosis of obstructive sleep apnea (OSA) in adults..
- Trial name
- NCT03748771
- Testing
- ApneaLink Air
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ResMed
Sleep Apnea
Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea
The purpose of this research study is to determine the effect of chronic nighttime low oxygen saturations on selected body systems (liver) that break down drugs in children with obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT00310323
- Testing
- Dextromethorphan, Caffeine
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Virginia Commonwealth University
Obstructive Sleep Apnea, Child, Only
Study of Postoperative Respiratory Complications in Children With Obstructive Sleep Apnea (PORC)
Adenotonsillectomy is the first line surgical treatment for children with Obstructive Sleep apnea Syndrome (OSAS). Postoperative respiratory complications (PORC) may occur and are often related to co-morbidities.
- Conditions
- Obstructive Sleep Apnea, Child, Only, Surgery
- Trial name
- PORC (NCT05308108)
- Testing
- (Adeno)tonsillectomy
- Where
- Belgium
- Volunteers
- 132 people
- Sponsor
- University Hospital, Antwerp
Sleep Apnea, Obstructive
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and propofol, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults…
- Trial name
- NCT01344759
- Testing
- Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain, Postoperative, Obstructive Sleep Apnea of Child
Use of Analgesics and Pain Scores After Pediatric Adenotonsillectomy
The purpose of the study is to quantify the use of pain medications given to children aged 3 - 12 years as well as their pain level through pain scores after they have undergone a tonsillectomy or adenotonsillectomy surgery at…
- Trial name
- NCT04349397
- Testing
- Medication Tracking Form
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Obstructive Sleep Apnea
Mucosal Inflammation in Children With OSA
Objectives: Variability of clinical phenotypes in childhood obstructive sleep apnoea (OSA) has prompted research for biomarkers to identify patients at risk of developing OSA-related complications.
- Trial name
- NCT06452979
- Where
- Hong Kong
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Adenoid Hypertrophy
Conventional Curettage Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy.
- Trial name
- NCT07856771
- Testing
- Conventional Curretage Adenoidectomy, Endoscopic Microdebrider-Assisted Adenoidectomy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Allama Iqbal Teaching Hospital
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Obstructive Sleep Apnea
Effect of Ketorolac on Post Adenotonsillectomy Pain
This randomized prospective study aims to determine the effect of ketorolac on the total dose of morphine required to achieve postoperative analgesia in children with obstructive sleep apnea (OSA) undergoing adenotonsillectomy.
- Trial name
- NCT03467750
- Testing
- Ketorolac, Standard of Care
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Emory University
Sleep Apnea, Obstructive, Child
Effect of CPAP and Adenotonsillectomy in Upper Airway Volume of Children With OSAS
Obstructive sleep apnea syndrome (OSAS) in children has high prevalence and severe complications, and its first line of treatment (adenotonsillectomy) has risk of complications.
- Conditions
- Sleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, Adenoidectomy
- Trial name
- NCT03169491
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Down Syndrome, Obstructive Sleep Apnea
Down Syndrome Obstructive Sleep Apnea
The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) with moderate to severe…
- Trial name
- DOSA (NCT06043440)
- Testing
- Oxygen
- Where
- 7 sites in United States
- Volunteers
- 230 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea of Child
BodySleep Algorithm for OSA Diagnosis in Children
Diagnosing obstructive sleep apnea-hypopnea syndrome in children (OSA) requires the performance of polysomnography (PSG) in the hospital which is sometimes challenging to perform in children, and time-consuming for installation…
- Trial name
- NCT07345312
- Testing
- Polysomnography
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France