Clinical trials: Obstructive Sleep Apnea-hypopnea Syndrome
Obstructive Sleep Apnea
Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.
The goal of this observational study is to characterize the performance of the SleepView+ home sleep test system for the evaluation of moderate to severe obstructuve sleep apnea (OSA) in adult and pediatric patients (ages 12 and…
- Trial name
- NCT07476313
- Testing
- SleepView+
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beacon Biosignals
Obstructive Sleep Apnea
Prospective Cohort Study of Patients Intolerant to High Pressure Under Continuous Positive Airway Pressure Treated With Bilevel Positive Airway Pressure as Second-line Therapy.
Prospective observational study of obstructive Sleep Apnea patients treated with Bilevel Positive Airway Pressure: AirCurve 10 VAutoTM
- Trial name
- PoP IN VAuto (NCT02930460)
- Where
- 8 sites in France
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
AutoSet for Her Clinical Trial Protocol
The purpose of this study is to assess the efficacy and user preference of the Newport AutoSet for Her in female obstructive sleep apnea (OSA) patients.
- Trial name
- NCT01826513
- Testing
- Standard AutoSet algorithm, Modified AutoSet algorithm
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Targeted Hypoglossal Neurostimulation Study #3
The purpose of this study is to evaluate the benefits and risks of hypoglossal nerve stimulation with the ImThera Medical aura6000 System as a potential therapeutic option for individuals with moderate to severe OSA that have…
- Trial name
- THN3 (NCT02263859)
- Testing
- aura6000 System
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 138 people
- Sponsor
- ImThera Medical, Inc.
Obstructive Sleep Apnea
Study of the Resvent RXiBreeze™ PAP System to Treat Obstructive Sleep Apnea
The goal of this clinical trial is to test the automatic positive airway pressure (APAP) function of the RXiBreeze PAP System in adult subjects with obstructive sleep apnea (OSA).
- Trial name
- NCT06008678
- Testing
- RXiBreeze PAP System, Model RXiBreeze 20A
- Where
- 9 sites in United States
- Volunteers
- 146 people
- Sponsor
- Resvent Holding USA LTD
Obstructive Sleep Apnea
Skiin-PSG Sleep Apnea
The goal of this observational study is to develop new algorithms to detect apnea and/or hypopnea to provide additional insights to Skiin users and to their circle of care to validate and/or improve the current algorithms of the…
- Trial name
- NCT06247878
- Testing
- Skiin underwear chest band
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Myant Medical Corp.
Sleep Disorders, Obstructive Sleep Apnea
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
The primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness in patients with obstructive sleep apnea/hypopnea…
- Conditions
- Sleep Disorders, Obstructive Sleep Apnea, Major Depressive Disorder, Dysthymic Disorder
- Trial name
- NCT00518986
- Testing
- armodafinil
- Where
- 62 sites in United States
- Volunteers
- 249 people
- Sponsor
- Cephalon
Obstructive Sleep Apnea, Insomnia
Evaluation of APAP With SensAwake in OSA and Insomnia Patients
The hypothesis is that APAP with SensAwake improves wake-after sleep onset compared to APAP without SensAwake in a patient population with Obstructive Sleep Apnea Syndrome (OSAS) and Insomnia.
- Trial name
- NCT02721329
- Testing
- APAP, APAP with SensAwake
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea, Sleep Apnea
Severe OSA Study (SOS)
This study is a prospective, multi-center, single-arm, open-label study evaluating the safety and effectiveness of therapy with the ProSomnus EVO Sleep and Snore Device in individuals with severe obstructive sleep apnea.
- Trial name
- NCT05445869
- Testing
- ProSomnus® EVO Sleep and Snore Device
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- ProSomnus Sleep Technologies
Obstructive Sleep Apnea
Developement of TipTraQ Home Sleep Test
The clinical study aims to develop and fine-tune the TipTraQ system, created by PranaQ, for home sleep apnea screening. The system comprises a wearable device and a cloud-based AI for estimating Total Sleep Time (TST) and…
- Trial name
- NCT06474351
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
OSA
Continuation Protocol for Obstructive Sleep Apnea (OSA)
The combination drug composed of aroxybutynin and atomoxetine, designated AD109, is being developed by Apnimed for the treatment of obstructive sleep apnea (OSA).
- Trial name
- NCT06566820
- Testing
- Aroxybutynin and Atomoxetine
- Where
- 99 sites in United States, Canada
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- Apnimed
Obstructive Sleep Apnea
PSG Validation of MATRx Plus AHI
Obstructive sleep apnea (OSA) is a common disease that carries significant risks for cardiovascular disease, mortality, and economic costs.
- Trial name
- NCT03627169
- Testing
- MATRx plus
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea, Central Sleep Apnea
Comparison of SomnaPatch With Polysomnography in Sleep Disordered Breathing
The purpose of this study is to evaluate the accuracy of Somnarus diagnostic technology for diagnosis of sleep apnea in human subjects.
- Conditions
- Obstructive Sleep Apnea, Central Sleep Apnea, Mixed Sleep Apnea, Cheyne-Stokes Respiration
- Trial name
- NCT02034175
- Testing
- SomnaPatch, Polysomnography
- Where
- 3 sites in United States
- Volunteers
- 190 people
- Sponsor
- Somnarus Inc
Obstructive Sleep Apnea
Analysis of a New Mask for Positive Airway Pressure (PAP) Device Users
BACKGROUND AND AIMS Continuous positive airway pressure (CPAP) is an effective therapy to treat sleep apnea. Sleep apnea is a condition where the airways collapse when the patient is asleep.
- Trial name
- NCT01847846
- Testing
- CPAP mask - prototype
- Where
- Australia
- Volunteers
- 23 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Evaluation of the Toffee Nasal and Toffee Nasal Pillows Mask in Home, USA, 2022
This clinical investigation is designed to assess the F\&P Toffee Nasal and Toffee Nasal Pillows masks in home for use during PAP therapy delivery.
- Trial name
- NCT05496062
- Testing
- F&P Toffee Nasal and Toffee Nasal Pillows Masks
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Fisher and Paykel Healthcare
Excessive Daytime Sleepiness, Narcolepsy
Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
A 12 Month, Open-Label, Flexible Dosage Extension Study of the Safety and Efficacy of Armodafinil (CEP-10953) in the Treatment of Patients with Excessive Sleepiness Associated with Narcolepsy, Obstructive Sleep Apnea/Hypopnea…
- Conditions
- Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Chronic Shift Work Sleep Disorder
- Trial name
- NCT00228553
- Testing
- Armodafinil 100 to 250 mg/day
- Where
- 100 sites in United States, Australia and 5 more
- Volunteers
- 743 people
- Sponsor
- Cephalon
Narcolepsy, Obstructive Sleep Apnea
The Nuvigil and Provigil Pregnancy Registry
The primary objective of the Nuvigil/Provigil Pregnancy Registry is to characterize the pregnancy and fetal outcomes associated with Nuvigil and Provigil exposure during pregnancy.
- Conditions
- Narcolepsy, Obstructive Sleep Apnea, Shift Work Sleep Disorder
- Trial name
- NCT01792583
- Testing
- Modafinil/armodafinil
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Cephalon, Inc.
Obstructive Sleep Apnea
Evaluation of a Nasal Mask for the Treatment of Obstructive Sleep Apnea in New Zealand
Currently, Fisher and Paykel Healthcare (FPH) is developing a new nasal mask. This investigation is designed to evaluate the performance of the trial nasal mask, focused specifically on how the different seal sizes will perform…
- Trial name
- NCT02541214
- Testing
- Trial Nasal Mask
- Where
- 2 sites in New Zealand
- Volunteers
- 39 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Study to Predict the Benefits of First-line Humidification Use and Comparison of the Effect of ThermoSmart™ and no Humidification on Adherence
This study aims to investigate the benefits of using first line heated humidification. The primary objective of this research is to determine the effect of high levels of humidification delivered by ThermoSmart™ on CPAP…
- Trial name
- NCT01742949
- Testing
- Heated humidification (ThermoSmart), No Humidification
- Where
- 4 sites in France
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis
Validation of an integrated digital solution (SUNrise®) of mandibular movement automatic analysis by artificial intelligence versus polysomnography for obstructive sleep apnea diagnosis: a prospective, randomized, parallel-arm…
- Trial name
- SUNSAS (NCT05057975)
- Testing
- Sunrise, polysomnography
- Where
- 19 sites in France
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Sunrise