Clinical trials: Obstructive Sleep Apnoea Hypopnoea Syndrome
Moderate Obstructive Sleep Apnea Syndrome
Upper Airway Reeducation in Moderate Obstructive Sleep Apnea Syndrome
The aim of this study is to evaluate the effectiveness of a specific reeducation performed by speech therapists in moderate obstructive sleep apnea syndrome, as an alternative to the continuous Positive Anyway Pressure (CPAP) and…
- Trial name
- SAOSGENIO (NCT05911971)
- Testing
- Experimental
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Head and Neck Cancer, Obstructive Sleep Apnea
Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve
Published data suggest that the glossopharyngeal nerve innervates pharyngeal musculature important for maintenance of upper airway patency.
- Trial name
- NCT05754216
- Testing
- Nerve stimulation using nerve stimulation device and sterile wire electrode.
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
Sleep Apnea, Obstructive, Delirium
Effect of CPAP on Postoperative Delirium
Patients with a medical condition known as obstructive sleep apnea may be at increased risk of delirium following surgery. This study loans autotitrating CPAP machines to randomly-selected patients who are at high-risk for…
- Trial name
- NCT01816685
- Testing
- CPAP
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Duke University
Obstructive Sleep Apnea (OSA)
The Efficacy of a New Mathematical Formula to Predict Continuous Positive Air Pressure With an Oronasal Mask Interface.
Subjects will all have a two week baseline period in which they will use a nasal mask using an air view CPAP machine (which records all data).
- Trial name
- NCT02816255
- Testing
- Full Face Mask with same CPAP Pressure, Full Face Mask with new Pressure
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University
Cholecystitis, Cholelithiasis
Outcome of IV Acetaminophen Use in Laparoscopic Cholecystectomies in Patients at Risk of OSA
The objective of this study is to determine if IV acetaminophen administered intraoperatively can decrease the dose of narcotics required for adequate pain control and shorten recovery time in the PACU specifically in obese…
- Conditions
- Cholecystitis, Cholelithiasis, Obstructive Sleep Apnea
- Trial name
- NCT02056678
- Testing
- acetaminophen, IV preparation
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Obstructive Sleep Apnea, Obesity
Lifestyle Modification Using an App in OSA
This study aimed to investigate the effects of a mobile phone app linked to hospital electronic medical record (EMR) system on weight reduction and obstructive sleep apnea (OSA).
- Trial name
- NCT03189940
- Testing
- Life style modification by using and app with a wrist-worn activity tracker, Conventional Life style modification
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Allergic Rhinitis, Sleep Disorder
Establishing the Collaborative Care Model for Pediatric Allergic Rhinitis With Sleep Disorder
The purpose of study is to compared the impact of the integrative care clinic to ordinary western medicine among patients of moderate persistent allergic rhinitis combined with sleep disorder and establishing the collaborative…
- Trial name
- NCT05031793
- Testing
- TCM, Western medicine
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- China Medical University Hospital
Obstructive Sleep Apnea
DISE-HNS Effect Study
The purpose of this study is to assess the site, pattern and degree of upper airway collapse before and during hypoglossal nerve stimulation (HNS) treatment using clinical standard drug-induced sleep endoscopy (DISE) and using a…
- Trial name
- DISE-HNS (NCT06372847)
- Testing
- Hypoglossal nerve stimulation implant, Polysomnography, Drug-induced sleep endoscopy (DISE)
- Where
- Belgium
- Volunteers
- 58 people
- Sponsor
- University Hospital, Antwerp
Sleep Apnea, Obstructive
Effects of Quetiapine on Sleep and Next Day Alertness in People With Obstructive Sleep Apnea
Quetiapine is medication used to treat schizophrenia and bipolar disorder. Increasingly, low doses of quetiapine are prescribed "off-label" for insomnia.
- Trial name
- QOSA (NCT05303935)
- Testing
- Quetiapine 50 MG
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Flinders University
Sleep Apnea, Obstructive
Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Device in the Diagnosis of Obstructive Sleep Apnea
A device has been developed which is placed under the mattress, thereby escaping contact with patient, which enables monitoring of sleep activity and has been shown in some studies to provide an estimate of the frequency of sleep…
- Trial name
- NCT04778748
- Testing
- Under-mattress sleep monitor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Transient Global Amnesia
PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at…
- Trial name
- PROTOS (NCT06903026)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Strasbourg, France
Sleep Apnea
A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery
The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.
- Trial name
- NCT05814016
- Testing
- Danavorexton
- Where
- 19 sites in United States
- Volunteers
- 41 people
- Sponsor
- Takeda
Down Syndrome, Obstructive Sleep Apnea
Down Syndrome Obstructive Sleep Apnea
The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) with moderate to severe…
- Trial name
- DOSA (NCT06043440)
- Testing
- Oxygen
- Where
- 7 sites in United States
- Volunteers
- 230 people
- Sponsor
- Brigham and Women's Hospital
Asthma, Obstructive Sleep Apnoea (OSA)
Is Asthma in Subjects With Obstructive Sleep Apnoea (OSA) Due to Dysanapsis
Intention to review patient letters from sleep clinic to see if their lung function fit in with Dysynapsis in wheezing patients or if it is true asthma
- Conditions
- Asthma, Obstructive Sleep Apnoea (OSA), Dysanapis
- Trial name
- NCT04142905
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)
This is a randomized controlled trial (RCT) of 4 weeks of study supplement N-acetylcysteine (NAC) versus placebo in persons with significant obstructive sleep apnea (OSA) who are receiving positive airway pressure therapy (PAP)…
- Trial name
- NCT06311045
- Testing
- N-acetylcysteine (NAC), Positive Airway Pressure (PAP) Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Sleep Apnea
Telemedicine Interventions for Obstructive Sleep Apnea (OSA)
This project is investigating whether both moderate-intensity physical activity and dietary weight loss will independently reduce sleep apnea symptoms and improve quality of life.
- Trial name
- NCT01108081
- Testing
- Physical activity, Diet, Health education
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea
New Approach in the Study of the Autonomic Nervous System Through Cardiac Variability in Sleep Apnea Syndrome.
The main objective of this study is to compare the different variations of the cardiac variability index measured thanks to the technique developed by the CIC-IT between subjects with severe SAS and healthy subjects with sleep…
- Trial name
- HRVSAS (NCT06808464)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Healthy, Obstructive Sleep Apnea
Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.
Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension.
- Trial name
- NCT00291993
- Where
- 3 sites in Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
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