Clinical trials: Obstructive Sleep Apnoea Hypopnoea Syndrome
Obstructive Sleep Apnea
Evaluation of a Novel Auto-Adjusting Positive Airway Pressure Algorithm for the Treatment of Obstructive Sleep Apnea Clinical Study
This study aims to assess the effectiveness of an investigational algorithm in the treatment of obstructive sleep apnea.
- Trial name
- NCT06769607
- Testing
- Investigational algorithm, Control algorithm
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- ResMed
COPD, Sleep Apnea Hypopnea Syndrome
Prediction of Exacerbations and Management of COPD Patients With SAH Based on Millimeter Wave Radar Monitoring
Millimeter wave radar will be used to conduct non-contact monitoring continuously for patients' vital signs (eg. respiratory rate, heart rate, and chest/abdominal movement).
- Conditions
- COPD, Sleep Apnea Hypopnea Syndrome, Acute Exacerbation of COPD
- Trial name
- NCT05019911
- Testing
- Polysomnography, Millimeter wave radar equipment
- Where
- China
- Volunteers
- 922 people
- Sponsor
- Peking University Third Hospital
Obstructive Sleep Apnea
A Study to Examine the Efficacy of a Therapeutic THX-110 for Obstructive Sleep Apnea
This is a sponsored proof of concept study with the purpose to examine the safety, tolerability and feasibility of THX-110 (Dronabinol (synthetic Δ9-THC) and PEA) for the treatment of adults with Obstructive Sleep Apnea.
- Trial name
- NCT03646552
- Testing
- THX-110
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Neurothera Labs Inc.
Chronic Obstructive Pulmonary Disease Exacerbation, Obstructive Sleep Apnea Exacerbation
Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure
Chronic obstructive pulmonary disease (COPD) is a major public health problem with 212.3 million prevalent cases of COPD worldwide and 3.3 million deaths related to COPD in 2019.
- Trial name
- NCT07047092
- Testing
- Non-invasive Ventilation (NIV), Continous Positive Airway Pressure (CPAP)
- Where
- France
- Volunteers
- 386 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Apnea, Obstructive, Type 2 Diabetes Mellitus
Effect of Oral Appliance Therapy on Glucose Levels in Patients With T2DM and OSA: A Pilot Trial
This study will evaluate the impact on blood glucose of the use of an oral appliance to treat obstructive sleep apnea (OSA) in individuals with Type 2 diabetes.
- Trial name
- NCT03167684
- Testing
- Oral appliance therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sleep Apnea
Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers
Previous studies have shown that programs encouraging the use of OSA treatments can help patients use these treatments more often, but the improvement is usually modest.
- Trial name
- BOOST (NCT07207473)
- Testing
- Behavioral strategy program X plus Y, Behavioral strategy program X
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Obesity, Bariatric Surgery Candidate
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome
It has been shown to date that obesity is associated with increased mortality and that weight loss significantly improves cardiovascular risk factors.
- Conditions
- Obesity, Bariatric Surgery Candidate, Apnea, Obstructive
- Trial name
- COLOSS (NCT04179188)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 400 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Ischemic Stroke, Sleep Apnea Syndrome
Screening and Treatment of SAHS in Patients With Acute Ischemic Stroke
Ischemic stroke is a kind of common disease with great harm. In acute stage of stroke there is sharply increasing morbidity of sleep apnea hypopnea syndrome.
- Trial name
- SAHS (NCT02029183)
- Testing
- Bi level positive pressure ventilation, bi-level positive airway pressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Coronary Artery Disease
Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)
1. Coronary artery bypass grafting (CABG) could be performed with or without extracorporeal circulation (ECC). 2. OSA (Obstructive Sleep Apnea) could be influenced by in intravenous perfusion. 3.
- Trial name
- NCT03743090
- Testing
- Polysomnography.
- Sponsor
- Astes
Obstructive Sleep Apnea (OSA), Pulmonary Hypertension
Echocardiographic Assessment of Pulmonary Hypertension in Obstructive Sleep Apnea
This study investigates the association between obstructive sleep apnea (OSA) and pulmonary hypertension (PH), focusing on the relationship between OSA severity and pulmonary arterial pressures in adult patients.
- Trial name
- NCT07184060
- Volunteers
- 55 people
- Sponsor
- Assiut University
Diabetic Nephropathy, Sleep Apnea
CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea
Objectives: Main objective: To assess the effect of 12 months of CPAP treatment added to conventional drug treatment on the albuminuria in patients with diabetic nephropathy and obstructive sleep apnea (OSA).
- Trial name
- DIANA (NCT02816762)
- Testing
- Continuous positive airway pressure, Pharmacological treatment, Diet
- Where
- 6 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Universitario La Paz
Obstructive Sleep Apnea Syndrome
Validation of Sleep Monitoring Algorithm Based on Smart Watches
In recent years, wearable devices are booming to enable not only the health monitoring but also the sleep efficiency assessment.
- Trial name
- NCT06696196
- Testing
- smart watches(wearable devices)
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Normotensive, Obstructive Sleep Apnea
Normotensive OSA Patients With Nondipper Circadian Blood Pressure Pattern
The principal objective is to evaluate the effect of CPAP treatment on blood pressure (BP) in normotensive patients with nondipper circadian pattern with sleep apnea-hypopnea syndrome (SAHS).
- Trial name
- Nondipper-OSA (NCT03987425)
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Pediatric Sleep Apnea
Collaborative Care Model for Allergic Rhinitis With Obstructive Sleep Apnea From Prevention to Treatment.
In this project,the investigators aim to establish a Collaborative Care Model of TCM and Western Medicine to improve the quality of life and symptoms of AR with OSA children and educate care-givers diet and massage information to…
- Trial name
- NCT04621513
- Testing
- laser acupuncture (RJ laser S/N 1813458), western medicine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Autism Spectrum Disorder (ASD), Obstructive Sleep Apnea (OSA)
Portable Sleep Monitors in Children With Autism Spectrum Disorder
The goal of this study is to evaluate the ability of a portable sleep monitor to detect obstructive sleep apnea in children with autism spectrum disorder (ASD). The main study objectives are to: 1.
- Trial name
- PrSM (NCT07367022)
- Testing
- Portable sleep monitor (Nox T3s)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Lena Xiao
Sleep Apnea, Obstructive
Obstructive Sleep Apnea Patients Treated With Mandibular Advancement Device
The purpose of this study is to evaluate efficacy of mandibular advancement device (MAD). on treating obstructive sleep apneas, symptoms, Apnea/Hypopnea Index (QHI) and the Respiratory Arousal Index (AHI/REI) and peripheral…
- Trial name
- NCT05621577
- Testing
- MANDIBULAR ADVANCEMENT DEVICE
- Where
- Iraq
- Volunteers
- 20 people
- Sponsor
- Hawler Medical University
Refractory Hypertension
Study of the Relationships Between Refractory Hypertension, Overweight/Obesity and Sleep Apnea Syndrome
The purpose of the study is to investigate the links between blood pressure (BP), overweight or obesity, and sleep apnea syndrome (SAS), by studying a large cohort of subjects suffering from refractory hypertension.
- Trial name
- RHOOSAS (NCT00746902)
- Testing
- nCPAP
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Obstructive, Respiratory Insufficiency
Monitored Saturation Post-ICU
The overall aim with this project is to describe the correlation between measured and charted saturation after intensive care and also describe the saturation-pattern in these patients.
- Trial name
- NCT02290236
- Testing
- Pulseoximetry
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Karolinska University Hospital
Multiple Sclerosis, Obstructive Sleep Apnea
Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis
This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS.
- Trial name
- SOMNUS (NCT04603196)
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Beth Israel Deaconess Medical Center
Obstructive Sleep Apnea Syndrome
Acoustic Pharyngometry in Obstructive Sleep Apnea Syndrome Patients, With Indication of Continuous Positive Air Pressure
Acoustic Pharyngometry (AP) is a method of measurement of Transversal Sectional Areas (TSA) and Volumes of oral cavity and pharynx, based on acoustic waves.
- Trial name
- APOSAS (NCT01210703)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
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