Clinical trials: Obstructive Uropathy
Renal Failure
Two Schedules of Hepatitis B Vaccination in Predialysis Chronic Renal Failure Patients
Patients with chronic renal disease have to be vaccinated as soon as dialysis is forestalled and this could improve seroconversion rate of hepatitis B vaccination.
- Trial name
- NCT01468051
- Testing
- four doses of Euvax B vaccine, 20 μg (1 ml) three doses of Euvax B vaccine
- Volunteers
- 51 people
- Sponsor
- Tehran University of Medical Sciences
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
Malaria, Schistosoma Mansoni
Leiden University Medical Center Mini Donor Bank
(Bio)medical research, particularly immunological, metabolic, transcriptional or biological assays, occasionally require the use of fresh blood (peripheral mononuclear cells) or urine.
- Conditions
- Malaria, Schistosoma Mansoni, Schistosoma Haematobium, Diabetes
- Trial name
- NCT02810613
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Obstructive Sleep Apnea, Overhydration
Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of decreasing fluid overload by hemodialysis on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease on intermittent hemodialysis.
- Conditions
- Obstructive Sleep Apnea, Overhydration, End Stage Renal Disease
- Trial name
- SASinHD (NCT01860209)
- Testing
- Hemodialysis
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Acute Calculous Anuria, Ureteral Calculi
Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria
Acute calculous anuria is a urological emergency caused by ureteral stone obstruction in a solitary functioning kidney or bilateral ureteral obstruction.
- Conditions
- Acute Calculous Anuria, Ureteral Calculi, Obstructive Uropathy, Acute Kidney Injury
- Trial name
- NCT07617948
- Testing
- Intravesical Aminophylline
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Beni-Suef University
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Efficacy of Mictalase® After ThuLEP
In this single-center, prospective, randomized, open label, phase-III study, patients with indication to Thulium Laser Enucleation of Prostate were enrolled. The report conformed to CONSORT 2010 guidelines.
- Trial name
- NCT05130918
- Testing
- Phenolmicin P3 and Bosexil suppository
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- San Carlo di Nancy Hospital
Anemia, Kidney Disease, Chronic
A Retrospective Observational Study of Hemoglobin Levels in Patients With Renal Anemia Treated With Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
This retrospective observational study will evaluate the hemoglobin levels in patients with renal anemia over 6 months treatment with Mircera (methoxy polyethylene glycol-epoetin beta).
- Trial name
- NCT01379963
- Where
- 17 sites in Greece
- Volunteers
- 780 people
- Sponsor
- Hoffmann-La Roche
Microcirculatory Status, Spectroscopic Analysis
Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease
Participants were selected based on three groups: healthy, chronic obstructive pulmonary disease, and chronic renal disease. NIRS was used to measure tissue oxygenation on the thenar region of the right hand.
- Conditions
- Microcirculatory Status, Spectroscopic Analysis, COPD, Renal Failure
- Trial name
- NIRS (NCT06976762)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Sleep Apnea, Chronic Kidney Diseases
Impact of Obstructive Sleep Apnea (OSA) Treatment on Blood Pressure Control in Chronic Kidney Disease
The role of obstructive sleep apnea (OSA) on chronic kidney disease (CKD) is not clear. This randomized clinical trial will test the impact of OSA treatment on blood pressure (BP) and on the estimated glomerular filtration rate…
- Trial name
- NCT05846490
- Testing
- CPAP, Usual care
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Urolithiasis, Strategy Training
Real-World Study of Obstructive Upper Urinary Tract Stones and Acute Pyelonephritis
Upper urinary tract stone obstruction complicated by acute pyelonephritis is a critical urological emergency requiring urgent decompression and infection control, yet real-world clinical decisions regarding the choice between…
- Conditions
- Urolithiasis, Strategy Training, Observation, Pyelonephritis Acute
- Trial name
- NCT07816991
- Testing
- Ureteral Stent, Percutaneous Nephrostomy, Initial Medical Therapy
- Volunteers
- 1,650 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Depression, ESRD
Morbidity and Mortality Among Dialysis Patients After Treatment for Depression
Morbidity and Mortality among Dialysis Patients after Treating Depression Objectives Our investigation has two objectives: 1. To assess whether treatment and recovery from depression decreases adverse clinical events in chronic…
- Trial name
- NCT00442429
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Portland VA Medical Center
Seriously Ill Patients, Cancer
Goals of Care Conversations Study
The long term goal is to improve quality of care in Veterans with serious illnesses by aligning medical care with Veterans' goals and values.
- Conditions
- Seriously Ill Patients, Cancer, Heart Failure, Interstitial Lung Disease
- Trial name
- LSTDI (NCT05001009)
- Testing
- Clinician Implementation Strategy Stage 1: low intensity clinician training, Clinician Implementation Strategy Stage 2: high intensity clinician training, Low patient engagement
- Where
- 3 sites in United States
- Volunteers
- 2,859 people
- Sponsor
- VA Office of Research and Development
Urinary Obstruction, Detrusor Underactivity
Delta Q Value to Discriminate Detrusor Underactivity From Bladder Outlet Obstruction
To determine the significance of delta Q value (Qmax - Qave) in discrimination between BOO and DU, to avoid invasive studies (pressure flow studies (PFSs)) and replace them with noninvasive study (uroflowmetry).
- Trial name
- NCT05359484
- Testing
- Uroflowmetry
- Where
- Egypt
- Volunteers
- 238 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea, IgA Nephropathy
The Effect of OSA on Severity and Prognosis of Patients With IgAN
This study aims to investigate the influence of obstructive sleep apnea hypopnea syndrome (OSA) on the severity and prognosis of patients with IgA nephropathy (IgAN), and to evaluate the therapeutic effect of continuous positive…
- Trial name
- NCT06393036
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Cancer, Congestive Heart Failure (CHF)
Outlook Quality of Life Intervention Study
The purpose of this study is to determine whether discussions of life story, forgiveness, and future goals improve quality of life for patients with serious illness.
- Conditions
- Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD)
- Trial name
- NCT01044290
- Testing
- Life Completion, Attention Control
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- VA Office of Research and Development
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Congenital Obstructive Megaureter
Primary Obstructive Megaureter Management in Eastern Interregional Area
Congenital obstructive megaureter is a urinary malformation affecting the ureterovesical junction and causing obstruction to the flow of urine. It is the second most common cause of hydronephrosis.
- Trial name
- POMME (NCT05639283)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Urologic Neoplasms
Antegrade Double-J Stent Placement for the Treatment of Malignant Obstructive Uropathy
Ureteral double- J stent is usually inserted by retrograde approach for the treatment of obstructed upper urinary tract. The antegrade approach, can a suitable alternative in certain situations without the need for general or…
- Trial name
- NCT04649970
- Testing
- Antegrade double-J stent
- Volunteers
- 174 people
- Sponsor
- Université de Sousse