Clinical trials: Obstructive Uropathy
Bladder Dysfunction, Overactive Bladder
Noninvasive Ultrasound Assessment of Detrusor Dysfunction
The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.
- Conditions
- Bladder Dysfunction, Overactive Bladder, BPH With Urinary Obstruction
- Trial name
- NUADD (NCT05652023)
- Where
- United States
- Volunteers
- 2,023 people
- Sponsor
- Mayo Clinic
Stress Urinary Incontinence
Transobturator Subtrigonal Tape vs Transobturator Suburethral Tape for Stress Urinary Incontinence
Introduction: Minimally invasive procedures TOT (tension-free suburethral tape using transobturator approach)have been the standard for correction of SUI. However, around 28% of these patients exhibit alteration of urinary flow.
- Trial name
- S-TOTvsTOT (NCT02112591)
- Testing
- transobturator subtrigonal tape S-TOT, Transobturator suburethral tape (TOT)
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
BPH With Urinary Obstruction, Male
Holmium Laser vs Bipolar Enucleation of a Large Volume BPH: a Randomised Controlled Study
To compare bipolar plasmakinetic enucleation versus holmium laser enucleation for management of large BPH.
- Trial name
- BPH (NCT03998150)
- Testing
- Holmium laser enucleation of the prostate, Bipolar plasma kinetic enucleation of the prostate
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Renal Colic, Pain
Analgesic Efficacy of Intranasal Desmopressin in Acute Renal Colic
In this study we will compare pain intensity and side effects at different time points after the intranasal administration of desmopressin or placebo in patients with acute renal colic pain.
- Trial name
- NCT01742689
- Testing
- Desmopressin intranasal spray, Indomethacin suppository
- Where
- 2 sites in Iran
- Volunteers
- 88 people
- Sponsor
- Tehran University of Medical Sciences
Overactive Bladder, Obstructive Sleep Apnea
Tolterodine Relieves Overactive Bladder Symptoms in Women With Moderate-to-severe Obstructive Sleep Apnea Syndrome
In this study, we aim to determine whether combined tolterodine and CPAP therapy is a more effective treatment for patients with OSAS than CPAP treatment only.
- Conditions
- Overactive Bladder, Obstructive Sleep Apnea, Overactive Bladder Syndrome
- Trial name
- NCT05250245
- Testing
- Tolterodine Tartrate 4 MG, Continuous positive airway pressure therapy (CPAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Obstructive Sleep Apnea, End Stage Renal Disease
Effect of Beginning a Renal Replacement Therapy on Obstructive Sleep Apnea in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of beginning a renal replacement therapy on fluid overload and its consequence on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease.
- Trial name
- SASinHD_005 (NCT02073344)
- Testing
- Renal replacement therapy, no intervention
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Prostatic Neoplasm, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for Obstructive Uropathy Due to Prostate Cancer
The aim of this study is to investigate the safety and efficacy of prostatic artery embolization of patients with recurrent symptoms secondary to locally advanced prostatic cancer including pelvic pain, bleeding or need for…
- Conditions
- Prostatic Neoplasm, Lower Urinary Tract Symptoms, Urological Manifestations, Prostatic Diseases
- Trial name
- NCT03104907
- Testing
- Prostatic Artery Embolization
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Overactive Bladder, Fecal Incontinence
InterStim Micro Post Market Clinical Follow-up Study (ELITE)
Post-market clinical follow-up for continued assessment of safety and performance to confirm long-term outcomes of the InterStim Micro System for sacral neuromodulation.
- Conditions
- Overactive Bladder, Fecal Incontinence, Non-obstructive Urinary Retention
- Trial name
- ELITE (NCT04506866)
- Testing
- InterStim Micro
- Where
- 24 sites in United States, Canada and 4 more
- Volunteers
- 148 people
- Sponsor
- MedtronicNeuro
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Myocardial Infarction With Non-obstructive Coronary Arteries, Grow Stimulation Expressed Gene 2
Rapid Identification of MINOCA Based on Novel Biomarkers
Among the patients diagnosed as acute myocardial infarction by coronary angiography, 5%-25% of the patients did not find coronary artery obstructive lesions. These patients do not need PCI.
- Conditions
- Myocardial Infarction With Non-obstructive Coronary Arteries, Grow Stimulation Expressed Gene 2, Copeptin, Identification
- Trial name
- NCT04974320
- Testing
- blood biomarkers
- Where
- China
- Volunteers
- 2,616 people
- Sponsor
- Qilu Hospital of Shandong University
Anemia, Diabetes, Kidney Disease, Chronic, Hypertension
Study of Anemia in Chronic Kidney Disease (CKD) Among High-Risk Hypertensive and Diabetic Patients in Pakistan
The purpose of this study is to evaluate the prevalence of CKD-related anemia at an early stage through screening of high-risk patients in Pakistan at the level of physicians, cardiologists, and diabetologists.
- Trial name
- NCT02444845
- Where
- 3 sites in Pakistan
- Volunteers
- 246 people
- Sponsor
- Hoffmann-La Roche
Ureteral Obstruction
Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction
The purpose of this study is to determine whether combination therapy with Tolterodine ER and Tamsulosin is more effective than monotherapy with tamsulosin alone in reducing stent symptoms.
- Trial name
- NCT01741454
- Testing
- Tamsulosin, Tolterodine ER
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Wisconsin, Madison
Obstructive Sleep Apnea, End Stage Renal Disease
Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients
The purpose of this study is to prospectively evaluate the impact of sleep apnea on the cardiovascular morbidity and mortality of patients with end-stage renal disease.
- Trial name
- SASinHD_003 (NCT02073305)
- Testing
- No Sleep Apnea, Sleep Apnea - untreated, Sleep Apnea - treated
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
BPH With Urinary Obstruction, Male
HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH
To compare bipolar resection versus holmium laser enucleation for management of symptomatic large BPH (> 80 gm)
- Trial name
- NCT04935151
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- 2 sites in Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Infection, Heart Failure
Hospital-Level Care at Home for Acutely Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03203759
- Testing
- Home hospitalization, Traditional inpatient hospitalization
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury, Urinary Tract Obstruction
Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department
Acute kidney injury (AKI) is a common diagnosis in the emergency department (ED), and urinary tract obstruction is a contributing cause that requires rapid diagnosis and therapeutic management.
- Trial name
- NCT06040736
- Where
- France
- Volunteers
- 155 people
- Sponsor
- University Hospital, Montpellier
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Conditions, Infections
Analysis of the Virtual Acute Care at Home Experience
The purpose of this study is to examine the implementation, intervention effectiveness, and dissemination of a digital acute care delivery model for improving selected health outcomes in the Hospital at Home population.
- Conditions
- Conditions, Infections, Heart Failure, Renal and Urinary Disorders
- Trial name
- HaH (NCT05952999)
- Testing
- Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
- Where
- United States
- Volunteers
- 9,654 people
- Sponsor
- OSF Healthcare System