Clinical trials: Obstructive Ventilation Disorder
Obstructive Sleep Apnea
Sleep Apnea Video Education for CPAP (SAVE-CPAP)
The purpose of this study is to determine how satisfied patients are when undergoing an overnight polysomnogram (sleep study), what their knowledge about sleep apnea is, and what factors affect obstructive sleep apnea (OSA)…
- Trial name
- SAVE-CPAP (NCT02553694)
- Testing
- Enhanced education, Usual education, Usual follow up
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea
The Effect of Positive Airway Pressure on Heart Rate Variability
This study is designed to determine the effect of continuous positive airway pressure (CPAP) or bi-level positive airway pressure (BiPAP) on heart rate variability (HRV) in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT00289666
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Christiana Care Health Services
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (PAP) Titration and Treatment Versus Auto-adjusting PAP Treatment for Sleep Apnea
The purpose of this randomized prospective study is to compare the efficacy of two approaches to initiate Positive Airway Pressure (PAP) treatment in patients diagnosed as having obstructive sleep apnea (OSA) by portable…
- Trial name
- NCT00988351
- Testing
- Continuous positive airway pressure, Auto-adjusting positive airway pressure treatment
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- North Florida Foundation for Research and Education
Obstructive Sleep Apnea
Anxiety and Depression In Patients With Obstructive Sleep Apnoea Before and After Continuous Positive Airway Pressure
Continuous positive airway pressure (CPAP) is the gold-standard treatment for obstructive sleep apnoea (OSA), the most common sleep-disordered breathing in the overall population.
- Trial name
- ADIPOSA (NCT04104880)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Granada
Acute Decompensated Heart Failure, Obstructive Sleep Apnea
Motivational Enhancement - Acute Decompensated Heart Failure and OSA
A feasibility randomized controlled trial will be conducted with a 6-month follow up to: Examine the impact of early intensive telemedicine motivational enhancement (TIME) vs standard of care on PAP adherence (n=40/group) and…
- Conditions
- Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
- Trial name
- NCT04752462
- Testing
- Telemedicine Intensive Motivational Enhancement
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Obstructive Sleep Apnea
Effectiveness and Safety of cNEP in Ethnic Japanese With Obstructive Sleep Apnea
The aim of this study is to evaluate the effectiveness and safety of cNEP (continuous negative external pressure) for the treatment of obstructive sleep apnea during two weeks of home use in subjects of Japanese ethnicity.
- Trial name
- NCT03375905
- Testing
- cNEP
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Sommetrics, Inc.
Sleep Apnea, Obstructive
Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea
It is unknown whether passive myofunctional appliances can be used for the treatment of obstructive sleep apnea and snoring, nor how to select the appropriate size per individual patient.
- Trial name
- NCT05497180
- Testing
- passive myofunctional appliance, standard oral appliance
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alberta
COPD
TELE-monitoring in Chronic Obstructive Pulmonary Disease
COPD is the fourth cause of death worldwide and it is expected to be the third in 2020. Non-invasive ventilation (NIV) has a positive impact in reducing mortality related to chronic respiratory failure in stable patients with…
- Trial name
- TELECOPD (NCT03129477)
- Testing
- Telemonitoring in noninvasive ventilation
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Conde, Bebiana, M.D.
Obesity Hypoventilation Syndrome
The Obesity-hypoventilation Syndrome Study of Clinical Characteristics and Predictive Factors of Response to Treatment
Main objective: To describe clinical and functional characteristics of the obese hypoventilating patient; to study the relation between the obesity-hypoventilation syndrome (OHS) and the obstructive sleep apnea hypopnea syndrome…
- Trial name
- NCT00938977
- Testing
- CPAP, Bilevel Support Ventilation (Non-Invasive Ventilation)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Sleep, Obstructive Sleep Apnea
Study Watch Sleep Metric Performance Characterization Study
This is a multi-center, single-arm, prospective performance evaluation study designed to assess performance of sleep metrics calculated from sensor data that is collected from two versions of the Verily Study Watch as compared to…
- Conditions
- Sleep, Obstructive Sleep Apnea, Insomnia
- Trial name
- NCT05276362
- Testing
- Study Watch, Actiwatch
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Verily Life Sciences LLC
Obstructive Sleep Apnea
The Influences of Intervention With Home-based Recovery Activity in Obstructive Sleep Apnea Syndrome
Background: OSAS is a type of sleep disorder characterized by intermittent, partial or complete upper airway (UA) collapse, seriously impacting sleep apnea and respiratory insufficiency.
- Trial name
- OSAS (NCT02278094)
- Testing
- Tongue Muscle Trainer (TMT), Threshold Inspiratory Muscle Trainer (TIMT), Walking Exercise
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Cheng-Kung University Hospital
Obesity Hypoventilation Syndrome (OHS)
Functional Capacity, Sleep Quality, and Cognitive Function in Obesity Hypoventilation Syndrome
Introduction: Obesity Hypoventilation Syndrome (OHS) is defined as the coexistence of obesity (BMI ≥ 30 kg/m²), daytime hypercapnia (PaCO₂ > 45 mmHg) in the absence of other causes of hypoventilation, and sleep-disordered…
- Trial name
- NCT07147153
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Bezmialem Vakif University
Sleep Apnea, Sleep Apnea, Obstructive
Proof-of-Concept Study to Determine the Flow Changes When Stimulating Two Neural Targets for the Treatment of Obstructive Sleep Apnea
This proof-of-concept study will evaluate the impact of surgically placing and stimulating the hypoglossal nerve and/or a second neural target Ansa Cervicalis, with a set of off-the-shelf electrode arrays.
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes
- Trial name
- NCT06415981
- Testing
- Hypoglossal nerve and/or Ansa Cervicalis stimulation
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Invicta Medical Inc.
Asthma, Lung Function Decreased
Dietary Intake in Adults From the GA2LEN Folow-up Survey
The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
- Conditions
- Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation
- Trial name
- NCT03251157
- Testing
- Dietary intake of various nutrients, foods and biocompounds
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Respiratory Disorders, Asthma and Rhinitis
Bioequivalence of GW483100 10 Milligram (mg) Tablets in Healthy Subjects Under Fasting Conditions
This study is conducted to determine whether the test product (GW483100 10 mg containing montelukast sodium equivalent to 10 mg of montelukast) is bioequivalent to the reference montelukast sodium 10 mg tablets (innovator…
- Trial name
- NCT02658422
- Testing
- Test Montelukast, Reference Montelukast
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obstructive Sleep Apnea
"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"
This trial is a 6-week, double-blind, placebo-controlled, randomized-withdrawal, multicenter study of safety and efficacy of JZP-110 in the treatment of excessive sleepiness in adult subjects with OSA.
- Trial name
- OSA (NCT02348619)
- Testing
- JZP-110
- Where
- 30 sites in United States, Finland and 3 more
- Volunteers
- 174 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Cough, OSA
Sham CPAP vs. Straight CPAP for Chronic Cough
Chronic cough is an important clinical problem in primary care and sub-specialty practice. Besides the distress experienced by patients with chronic cough, significant healthcare resources are expended to understand the role of…
- Trial name
- NCT03172130
- Testing
- Straight CPAP
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Krishna M. Sundar
Chronic Obstructive Pulmonary Disease
COPD Breathing Record Study 2
The aim of this study is to collect capnometric (tidal breathing CO2) data using TidalSense's N-Tidal C Data Collector Device. The data collected will be examined for correlation with currently accepted assessment techniques for…
- Trial name
- CBRS2 (NCT03615365)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- TidalSense
Hypercapnic Respiratory Failure, Sleep Disordered Breathing
Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation
Patients are invited to participate in a trial to test a new way to optimise long-term use of non-invasive ventilation using remote monitoring.
- Conditions
- Hypercapnic Respiratory Failure, Sleep Disordered Breathing, COPD, Obesity Hypoventilation Syndrome (OHS)
- Trial name
- READ-NIV (NCT04884165)
- Testing
- Remote monitoring of home mechanical ventilation (NIV) using SRETT, Home mechanical ventilation (NIV) without remote monitoring
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obstructive Sleep Apnea, Upper Airway Resistance Syndrome
Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome
Tongue exercises are described to improved snoring and acid reflux symptoms. Acid reflux treatment has been found to improve obstructive sleep apnea to a limited degree.
- Conditions
- Obstructive Sleep Apnea, Upper Airway Resistance Syndrome, Gastroesophageal Reflux
- Trial name
- NCT00364481
- Testing
- omeprazole, Tongue exercises
- Volunteers
- healthy volunteers welcome
- Sponsor
- West Side ENT
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.