Clinical trials: Obstructive Ventilation Disorder
Sleep Apnea, Obstructive
Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy
Hemostasis will be achieved during Pediatric Tonsillectomy/Adenoidectomy with the use of QuickClot.
- Trial name
- NCT01863563
- Testing
- QuickClot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Eastern Virginia Medical School
Respiratory Disease
Luftibus in the School: a Study on the Respiratory Health of Schoolchildren.
This study assessed the respiratory health of schoolchildren from the canton of Zurich by combining self-reported information on respiratory symptoms with lung function test results and air pollution measurements.
- Trial name
- LUIS (NCT03659838)
- Where
- Switzerland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Obstructive Sleep Apnea, Restless Leg Syndrome
New Data Analysis Methods for Actigraphy in Sleep Medicine
The purpose of this study is to develop statistical and informatics tools for analyzing and visualizing Actical™ (actigraphy) data linked to fatigue in Sleep Medicine Center patients.
- Conditions
- Obstructive Sleep Apnea, Restless Leg Syndrome, Insomnia
- Trial name
- NCT00949858
- Where
- United States
- Volunteers
- 635 people
- Sponsor
- Washington University School of Medicine
Hypertension, Resistant to Conventional Therapy, Obstructive Sleep Apnea
CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension
Resistant hypertension is defined as uncontrolled blood pressure (BP ≥ 140/90mmHg) despite the current use of three or more antihypertensive drugs at full doses, including a diuretic.
- Trial name
- POP-ART (NCT02385864)
- Where
- 4 sites in France
- Volunteers
- 166 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Respiratory Drive on Obstructive Apnea
This study is being conducted to determine whether inhaling exhaled carbon dioxide is effective for the treatment of sleep apnea.
- Trial name
- NCT01961648
- Testing
- Rebreathing bag, Mask
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Emphysema, Acute Respiratory Distress Syndrome
Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure
A new artificial lung device has been developed that potentially provides added support to mechanical ventilation for severely damaged lungs.
- Conditions
- Emphysema, Acute Respiratory Distress Syndrome, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT00288964
- Testing
- Hattler Respiratory Assist Catheter
- Where
- United Kingdom
- Sponsor
- Alung Technologies
Chronic Obstructive Pulmonary Disease
Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude
In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on sleep related breathing disturbances at altitude in patients with COPD.
- Trial name
- NCT03177850
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 185 people
- Sponsor
- University of Zurich
COPD
Comparative Effects of Wim Hoff Method and Box Breathing Method in Mild COPD
The goal of this clinical trial is to support the role of effective, non-pharmacological interventions in the management of the symptoms of mild Chronic Obstructive Pulmonary Disease (COPD) or the anxiety, dyspnea, and peak…
- Trial name
- NCT07506317
- Testing
- Box Breathing, Wim Hoff Breathing Technique
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Sleep Apnea, Obstructive
Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults
In this protocol the investigators will test the effect of dalfampridine (a potassium channel blocker) on genioglossus muscle activity (EMG GG) during wakefulness and sleep in healthy control subjects.
- Trial name
- APIGLOSS (NCT02656160)
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive, Obesity
Life-style Changes in Obstructive Sleep Apnea
The primary aim is to study whether a tailored behavioural medicine intervention addressing physical activity and eating habits have additional effects to continuous positive airways pressure (CPAP) in patients with moderate or…
- Trial name
- NCT01102920
- Testing
- Behavioural strategies to promote physical activity and weight loss, CPAP
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Uppsala University
Chronic Obstructive Pulmonary Disease
Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease
Some patients with Chronic Obstructive Pulmonary Disease (COPD) report that they are uncertain whether they achieve clinical benefit using a dry-powder inhaler (DPI).
- Trial name
- NCT01391559
- Testing
- arformoterol, salmeterol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obstructive Sleep Apnea
Oropharyngeal Exercises to Treat Obstructive Sleep Apnea
The goal of this study is to determine whether a randomized controlled trial using oropharyngeal exercises to treat sleep apnea is feasible.
- Trial name
- NCT05678088
- Testing
- Oropharyngeal Exercises
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obstructive Sleep Apnea
Workflow Validation of an In-Home Feedback Controlled Mandibular Positioner
The purpose of the study is to test the workflow of the MATRx and MATRx plus feedback controlled mandibular positioner in its intended setting and considerations related to decision making by the care provider.
- Trial name
- NCT03616327
- Testing
- MATRx in-lab, MATRx plus
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Zephyr Sleep Technologies
Chronic Obstructive Pulmonary Disease
Combined Effects of Ba-Duan-Jin Based Deep Breathing Exercises and Forced Expiratory Technique
This study will be a randomized control trial. A total of 68 patients will be recruited and randomly assign to the experimental group or the control group in a 1:1 ratio.
- Trial name
- NCT06332417
- Testing
- Ba-Duan-Jin Based Deep Breathing Exercises, FET (Forced Expiratory Technique)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV; part2
The purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea, increase activity and have impact on parasympathetic activities.
- Trial name
- NCT01905982
- Testing
- reflectory breathing therapy, conventional breathing therapy
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Obesity Hypoventilation Syndrome
Prevalence of Obesity Hypoventilation Syndrome
Rationale of the "BIO-OHS" study (Prevalence of Obesity Hypoventilation Syndrome): The overall prevalence of Obesity Hypoventilation Syndrome (OHS) has never been directly assessed in the general population.
- Trial name
- BIO-OHS (NCT01903135)
- Testing
- Blood test analysis in the clinical labs, Pneumologist consult to establish the diagnosis of OHS
- Where
- 5 sites in France
- Volunteers
- 1,004 people
- Sponsor
- AGIR à Dom
Chronic Obstructive Pulmonary Disease
A Novel Unidirectional Face Mask During NPPV in COPD Patients
The purpose of this study is to determine the feasibility, safety and efficacy of a unidirectional breathing mask (breathe in through the nose and out through the mouth or breathe in through the mouth and out through the nose) in…
- Trial name
- NCT00972868
- Testing
- A unidirectional face mask (Modified 'Respironics PerformaTrak' Mask)
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Severe Persistent Asthma
Inhaled Steroids and Control of Severe Asthma
Investigational device: AKITA 2 device versus conventional metered-dose inhaler (MDI) Objectives: To explore if inhalative fluticasone application by means of the AKITA technology would result in a better symptom control in…
- Trial name
- INHALE (NCT01197482)
- Where
- 3 sites in Germany
- Volunteers
- 6 people
- Sponsor
- University of Giessen
COPD (Chronic Obstructive Pulmonary Disease), Airway Disease
Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry.
- Trial name
- BREATHE (NCT07798596)
- Testing
- Capnography, Oscillometry, FENO
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.