Clinical trials: Obstructive Ventilation Disorder
OBSTRUCTIVE SLEEP APNEA
Obstructive Apnea in Patients Submitted to Partial Laryngectomy
The investigators intend to study the prevalence of obstructive apnea in patients submitted to partial laryngectomy by larynx cancer. Volunteers will be evaluated using polissonografy.
- Trial name
- NCT01157286
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital do Servidor Publico Estadual
Obstructive Sleep Apnea
Pilot Study of Negative Pressure Sleep Therapy System to Treat Obstructive Sleep Apnea
This is a pilot study to investigate the efficacy and safety of the Negative Pressure Sleep Therapy System for the treatment of obstructive sleep apnea.
- Trial name
- NCT02324790
- Testing
- iNAP® Sleep Therapy System
- Where
- 4 sites in Taiwan
- Volunteers
- 34 people
- Sponsor
- Somnics, Inc.
Sleep Apnea
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
The purpose of this research is to see how effective the Personalized obstructive sleep apnea (OSA) Treatment Adherence Model called PRAISE is in helping the patient stick to the physician recommended OSA treatment plan Positive…
- Trial name
- PRAISE (NCT06089161)
- Testing
- Standard of Care, Personalized OSA Treatment
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of Miami
Metabolic Syndrome, Insulin Resistance
Impact of Obstructive Sleep Apnea Syndrome on Metabolic Syndrome in Severe Obesity
The aim of this project is to study the relationship between obstructive sleep apnea (OSA) and metabolic syndrome (MS) in a population of obese patients who are candidates for bariatric surgery.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Adipokines, Cytokines
- Trial name
- SYBILA (NCT01029561)
- Testing
- CPAP, Diet
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Hospital Universitari de Bellvitge
Bronchiolitis, Acute Bronchiolitis
Risk Factors and Severity of Bronchiolitis in Hospitalized Children at Assiut University Hospital
The purpose of this observational study is to identify the risk factors that make bronchiolitis more severe in infants and toddlers.
- Conditions
- Bronchiolitis, Acute Bronchiolitis, Respiratory Syncytial Virus Infection
- Trial name
- NCT07505420
- Volunteers
- 65 people
- Sponsor
- Assiut University
Obstructive Sleep Apnoea Syndrome
Identification of Biomarkers for Obstructive Sleep Apnoea Syndrome
Untreated Obstructive Sleep Apnea Syndrome (OSAS) has long-term complications, namely metabolic imbalances (obesity, dislipidemia, type 2 diabetes mellitus).
- Trial name
- NCT02043483
- Where
- Portugal
- Volunteers
- 120 people
- Sponsor
- Universidade Nova de Lisboa
Pulmonary Arterial Hypertension, Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) in Pulmonary Arterial Hypertension (PAH)
The purpose of this study is to determine whether pulmonary arterial hypertension can worsen or even cause sleep apnea. It is hypothesized that if pulmonary arterial hypertension does indeed worsen or cause sleep apnea, then the…
- Trial name
- NCT01835080
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
NRS 2002 as a Predictor of Prognosis in COPD With Respiratory Failure
This is a prospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during April 2017 to March 2019.
- Trial name
- NCT02942797
- Where
- China
- Volunteers
- 520 people
- Sponsor
- West China Hospital
Pulmonary Disease, Chronic Obstructive, E-cigarettes
Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study
Determination of the acute pulmonary toxicities of e-cigarettes in young adults is of major public health importance, as e-cigarette vapor contains established toxicants that as hypothesized cause acute damage to the airways and…
- Trial name
- VaPE-Tox (NCT02783768)
- Testing
- E-cigarette, Hyperpolarized 3-Helium, Gadolinium
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
COPD
Effects of Blow Bottle Verses ACBTs Technique in Patients of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a common disease worldwide. Pulmonary rehabilitation is an important part to decrease the complications of COPD.
- Trial name
- NCT06189196
- Testing
- BLOW BOTTLE, ACBT
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Insomnia, Obstructive Sleep Apnea
Treatment of Insomnia in Elderly Sleep Apnea Patients With Ramelteon (TAK 375)
The objective of the study is to determine if treatment with Ramelteon will help to improve insomnia in older adults with co-existent insomnia and sleep apnea. The primary study objective is sleep latency (a measure of insomnia).
- Trial name
- NCT01048242
- Testing
- rozerem
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea (OSA)
Validation of Five Seasons Sleep Tracking Mat for the Diagnosis of Obstructive Sleep Apnea
This study will evaluate and compare the diagnostic accuracy and effectiveness of the Five Seasons Sleep Tracking Mat with the gold standard, polysomnography.
- Trial name
- NCT06875479
- Testing
- Five Seasons [5S] Sleep Tracking Mat
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai 6th People's Hospital
Obstructive Sleep Apnea, Adverse Effects
Comparison of Nasal Positive End Expiratory Pressure Valve to Dental Device as an Alternative Treatment for Obstructive Sleep Apnea
Determine the clinical efficacy in terms of Apnea Hypopnea Index (AHI), excessive daytime sleepiness (EDS), nocturnal oxygenation of a nasal Positive end-expiratory pressure (PEEP) valve "Provent" in obstructive sleep apnea.
- Trial name
- NCT01553383
- Testing
- nasal peep valve "Provent"
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Chronic Obstructive Pulmonary Disease, Lung Disease
Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to find out if AZD2423 can reduce inflammation in the lungs of patients with mild COPD.
- Trial name
- NCT01153321
- Testing
- AZD2423
- Where
- Germany
- Volunteers
- 71 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Respiratory Muscle Activations During Stable Threshold Load and Increasing Threshold Load Endurance Tests in COPD
In the literature, it has been observed that there is an increase in respiratory muscle activity in individuals with COPD due to the increase in respiratory workload and in response to the loads given by respiratory muscle…
- Trial name
- NCT04983485
- Testing
- Observational
- Volunteers
- 21 people
- Sponsor
- Abant Izzet Baysal University
Chronic Obstructive Pulmonary Disease, Hypercapnia
Non-invasive Home Ventilation in Patients With Severe Hypercapnic Chronic Obstructive Pulmonary Disease
In COPD patients with chronic hypercapnic respiratory failure, the prognosis is poor and the treatment with non invasive ventilation is actually well established. However the best mode of ventilation is not well known.
- Trial name
- SOMNOVENT' (NCT03934749)
- Testing
- Non Invasive Ventilation
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Obstructive Pulmonary Disease
Physiological Study of Minimally Invasive ECCO2R in Exacerbations of COPD Requiring Invasive Mechanical Ventilation
Morbidity and mortality in COPD result largely of acute exacerbations.The optimization of the respiratory management represents a fundamental challenge for improving prognosis and reducing mortality.
- Trial name
- EPHEBE (NCT02586948)
- Testing
- extracorporeal CO2 removal (Hemolung device)
- Where
- 3 sites in France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Respiratory Diseases, Bronchiolitis
Assessment of NeuroBOX and NeuroPAP in Infants.
Non-invasive ventilation (NIV, delivered via a mask or cannulas) permits to reduce the need for tracheal intubation in infants who needs a ventilatory support.
- Conditions
- Pediatric Respiratory Diseases, Bronchiolitis, Infant Respiratory Distress Syndrome
- Trial name
- NeuroPap2 (NCT03650478)
- Testing
- NeuroPAP ventilation (2h) and NeuroBox monitoring (23h), NeuroPAP ventilation (4h) and NeuroBox monitoring (25h)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Justine's Hospital
Obstructive Sleep Apnea (OSA), Polysomnography
Multimodal Deep Learning Model for Predicting the Apnea-Hypopnea Index in Obstructive Sleep
This study aims to develop a multimodal deep learning model that integrates noninvasive signals to predict the severity of obstructive sleep apnea.
- Trial name
- NCT07447999
- Testing
- electronic stethoscope, fingertip pulse oximeter, pressure-sensing mattresses
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Fu Jen Catholic University
Sleep Apnea
Revisiting Parental Survey for Screening for Obstructive Sleep Apnea in Patients Undergoing Polysomnography
The investigators are proposing a study where the investigators would give a survey to the parents of patients having a sleep study.
- Trial name
- NCT01914198
- Testing
- Sleep apnea symptom survey
- Where
- United States
- Volunteers
- 948 people
- Sponsor
- Vidya Raman
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