Clinical trials: Obstructive Ventilation Disorder
Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome
Sleep Disordered Breathing in Children With Single Ventricle Physiology
This is an exploratory study designed to evaluate the incidence of, and to quantify sleep disordered breathing following stage I Norwood reconstructive surgery. Sleep disordered breathing will be correlated with: 1.
- Conditions
- Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome, Single Ventricle Physiology
- Trial name
- NCT00156455
- Where
- United States
- Sponsor
- University of Rochester
Obesity Hypoventilation Syndrome
Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease
Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to identify potential determinants for the development of obesity hypoventilation to…
- Trial name
- NCT03854058
- Testing
- magnetic phrenic nerve stimulation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Obstructive Sleep Apnea
The Severity Of Individual Breathing Cessation Events In Diagnostics Of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common nocturnal breathing disorder characterized by complete (apnea) and partial (hypopnea) breathing cessations during sleep.
- Trial name
- NCT03232658
- Where
- 4 sites in Australia, Finland and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Loewenstein Hospital
Smoking, COPD
Canadian Cohort on the Origin and Progression of Airway Disease: Physiology Platform
The Canadian Respiratory Research Network (CRRN) has recently been established to study the origins and evolution of airways disease in the population.
- Trial name
- NCT02153684
- Where
- 3 sites in Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Dr. Denis O'Donnell
Rheumatic Valvular Heart Disease, Obstructive Sleep Apnea
CPAP Treatment and Postoperative Outcomes in Patients With Rheumatic Valvular Heart Disease
The prevalence of OSA (Obstructive sleep apnea，OSA) is 2%-4% in general population and 16%-47% in surgical-heart failure patients.
- Trial name
- CPAP (NCT03398733)
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Nanjing Medical University
Lymphedema, Obstructive Sleep Apnea Syndrome
Prevalence of Obstructive Sleep Apnea (OSA) in Patients With Lymphedema, Admitted for Intensive Decongestive Physiotherapy
Rehabilitation results in a decrease of the perimeters of the limb with lymphedema by a decrease in the amount of liquid of the affected limb, with movement of the intracellular liquid towards the trunk and the neck then into the…
- Trial name
- LYMPHOS (NCT02979184)
- Testing
- Intensive decongestive physiotherapy
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Grenoble
COPD, Chest Wall Disease
Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure
This study is looking at whether there is a difference in outcomes using two different types of breathing support in those patients who have chronic respiratory failure (patients who under-breathe).
- Conditions
- COPD, Chest Wall Disease, Neuromuscular Disease, Obesity Hypoventilation
- Trial name
- NCT00994552
- Testing
- Pressure support ventilation, Pressure control ventilation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Overlap Syndrome, Obesity Hypoventilation Syndrome
Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap Syndrome
High velocity nasal insufflation (HVNI), a form of HFNC that utilizes a small bore nasal cannula to generate higher velocities of gas delivery than HFNC which uses large bore cannula, has the ability to accomplish complete purge…
- Trial name
- HVNI (NCT05190458)
- Testing
- High Velocity Nasal Insufflation, Non-invasive mechanical ventilation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Asthma
Effect of Intranasal Corticosteroids on Pulmonary Symptoms in Asthmatics With Nasal Congestion
In this study we will investigate the effect of intranasal corticosteroid therapy, which is known to reduce mucosal inflammation and nasal blockage, on asthmatic symptoms.
- Trial name
- NCT01562093
- Testing
- corticosteroid nasal spray
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- St. Olavs Hospital
Obstructive Sleep Apnea, Hypertonia, Muscle
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).
- Conditions
- Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance
- Trial name
- NCT05527652
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
OSA, Obstructive Sleep Apnea
AD816 Crossover Study
The VicTor Study is a randomized, double blind, placebo-controlled, 3-period, multiple-dose crossover study in participants with OSA.
- Trial name
- VicTor (NCT05793684)
- Testing
- Period A, Period B, Period C
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Apnimed
Obstructive Sleep Apnea
Post-Market Observational Study of the WINX Sleep Therapy for the Treatment of Obstructive Sleep Apnea (OSA)
The objective of the Study is to observe the use and utility of the Winx Sleep Therapy System in a clinical practice, for the treatment of patients with obstructive sleep apnea (OSA).
- Trial name
- UNMASK (NCT01683721)
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- ApniCure, Inc.
Chronic Obstructive Pulmonary Disease (COPD), Whole Body Vibration
Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance.
- Trial name
- NCT07509606
- Testing
- Whole body vibration
- Where
- Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Obstructive Sleep Apnea
The Evaluation of the Toffee Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea
This investigation is a prospective, non-randomized, non-blinded study. This investigation is designed to evaluate the performance, comfort and ease of use of the F\&P Toffee nasal pillows mask amongst obstructive sleep apnea…
- Trial name
- NCT03242148
- Testing
- Toffee Nasal Pillows Mask
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fisher and Paykel Healthcare
Hypertension, Cardiac Function and Hemodynamics
AKTIIA OBPM to Assess CPAP Effect on Blood Pressure in Obstructive Sleep Apnea
The goal of this clinical trial is to learn if positive airway pressure (CPAP) therapy works for blood pressure (BP) control in obstructive sleep apnea (OSA) adult patients plus undiagnosed hypertension (HBP), using a cuffless…
- Conditions
- Hypertension, Cardiac Function and Hemodynamics, Usability, Patient Experience
- Trial name
- AVLA1 (NCT06446934)
- Testing
- CPAP
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario Araba
Obstructive Sleep Apnea
Validation of Sleep Apnea Screening Device Phase II
Obstructive sleep apnea (OSA) is the most common type of sleep apnea. The marketplace currently does not have an affordable, easy-to-use, over-the-counter, home-based OSA screening device.
- Trial name
- NCT03025464
- Testing
- Obstructive Sleep Apnea Screening Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Cough, Asthma
Validation of the C-mo System - Cough Monitoring
The goal of this clinical study is to validate C-mo System's ability to automatically detect and characterise cough, in patients over 2 years old with cough as a key or refractory symptom.
- Conditions
- Cough, Asthma, Chronic Obstructive Pulmonary Disease, Gastro Esophageal Reflux
- Trial name
- C-mo_01 (NCT05989698)
- Testing
- C-mo System
- Where
- 8 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Cough Monitoring Medical Solutions
Obstructive Sleep Apnea (OSAS)
Evaluation of Respiratory Muscle Sarcopenia in Obstructive Sleep Apnea Syndrome
OSAS is a disease characterized by repeated interruptions and restarts of breathing during sleep. Respiratory muscle sarcopenia is a condition in which the muscle strength of the diaphragm and other respiratory auxiliary muscles…
- Trial name
- RMS-OSAS (NCT06783998)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Tarsus University
Morbid Obesity, Metabolic Syndrome
Impact GLP-1 Agonists Following Bariatric
Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control hunger, induce satiety and plays a role in the metabolic…
- Conditions
- Morbid Obesity, Metabolic Syndrome, Diabetes Mellitus, Hypertension
- Trial name
- NCT06132477
- Testing
- GLP-1 receptor agonist
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Missouri-Columbia
Chronic Cough (CC), Asthma
The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges
The inhalation of adenosine 5'-triphosphate (ATP) to evoke cough (ATP cough challenge) is becoming increasingly used as a tool to measure cough hypersensitivity in patients with chronic cough.
- Trial name
- NCT07085975
- Testing
- Adenosine 5'-triphosphate
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
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