Clinical trials: Occlusion, Cerebrovascular
Intracranial Aneurysm, Stroke, Ischemic
Neurovascular Product Surveillance Registry
Post market surveillance registry
- Trial name
- INSPIRE (NCT02988128)
- Testing
- Treatment for intracranial aneurysms, Treatment for Acute Ischemic Stroke
- Where
- 99 sites in Argentina, Australia and 22 more
- Volunteers
- 4,000 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Coronary Artery Disease, Cerebral Stroke
Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease
Background: About 5% of patients with acute coronary syndrome (ACS) have had previously ischemic stroke (IS) or transitory ischemic attack (TIA).
- Conditions
- Coronary Artery Disease, Cerebral Stroke, TIA (Transient Ischemic Attack)
- Trial name
- NCT02316119
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Ischemic Stroke
The Vesalio NeVa Stent Retriever Study for Treatment of Large Vessel Occlusion Strokes
A prospective, open label, single-arm 90-day study designed to assess the safety, performance and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers.
- Trial name
- NCT03927001
- Testing
- NeVa Stent Retrievers
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Vesalio
Internal Carotid Artery Stenosis
Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis
This study aims to explore the efficacy of Intermittent Hypoxia Treatment (IHT) in preventing peri-operative embolism-related microinfarcts among patients with severe internal carotid artery stenosis (ICAS) undergoing carotid…
- Trial name
- NCT07837011
- Testing
- intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Capital Medical University
Intracranial Artery Occlusion With Infarction (Disorder)
RECO in the Endovascular Treatment of Acute Ischemic Stroke
Investigate Reco ® ,the first clot retriever in china as the primary therapyand remedies in the real world.
- Trial name
- NCT04840719
- Testing
- RECO
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery Stenosis, Atherosclerosis
Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis
The aim of this study is to determine whether optimal medical treatment can postpone carotid endarterectomy.
- Conditions
- Carotid Artery Stenosis, Atherosclerosis, Stroke
- Trial name
- AMTEC (NCT00805311)
- Testing
- Carotid Endarterectomy, atorvastatin, aspirin, losartan, amlodipine
- Where
- 2 sites in Russia
- Volunteers
- 400 people
- Sponsor
- Russian Cardiology Research and Production Center
Carotid Stenoses
Stroke and Panorama - Analyzing Carotid Endocalcifications (SPACE)
The odontological radiology method Panorama is known to be able to spot calcifications in the area of the carotid arteries. The calcifications could be carotid stenoses which is affiliated with an increased risk of stroke.
- Trial name
- SPACE (NCT00514644)
- Testing
- Carotid ultrasound examination, Panorama examination
- Where
- Sweden
- Volunteers
- 266 people
- Sponsor
- Umeå University
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Acute Ischemic Stroke, Atrial Fibrillation
Combination of Antiplatelet and Anticoagulation for AIS Patients Witn Concomitant NVAF and Extracranial/Intracranial Artery Stenosis
The goal of this clinical trial is to compare the safety and effectiveness of anticoagulation combined with antiplatelet therapy in acute ischemic stroke (AIS) patients with concomitant non-valvular atrial fibrillation (NVAF) and…
- Conditions
- Acute Ischemic Stroke, Atrial Fibrillation, Stenosis, Carotid, Intracranial Atherosclerosis
- Trial name
- ALLY (NCT06058130)
- Testing
- Anticoagulant Oral, Anticoagulation combined with antiplatelet therapy
- Where
- 2 sites in China
- Volunteers
- 2,171 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracranial Large Vessel Occlusion, Ischemic Stroke
EndovascularTherapy Versus Standard Medical Terapy for Intracranial Large Vessel Occlusion in 24 Hours to 30 Days
This study is a prospective, multicenter, observational cohort study using a real-world study design. The aim of this study is to compare functional and safety outcomes of intravascular recanalization therapy (with COSIS distal…
- Trial name
- NCT07843836
- Testing
- Endovascular Treatment Group, Standard medication
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xuan Sun
Diabetes Mellitus Type 2, Cardiovascular Diseases
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
To evaluate the proportion of diabetic mellitus patients with CV events as measured by HEMOTAG.
- Conditions
- Diabetes Mellitus Type 2, Cardiovascular Diseases, Coronary Artery Disease, Cerebrovascular Disease
- Trial name
- PRIZETAG (NCT06567795)
- Testing
- Hemotag
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- Aventusoft, LLC.
Moyamoya Disease
Family-Based Moyamoya Susceptibility and Early Detection
This single-center, prospective, family-based observational cohort study aims to investigate susceptibility to moyamoya disease (MMD) and to develop strategies for early screening in individuals at increased familial risk.
- Trial name
- FAMES (NCT07517354)
- Testing
- 5T High-Resolution MRI
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery Disease, Symptomatic Carotid Artery Stenosis
High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)
Goal is to analyse the clinical safety and efficacy of the CARESTO® heal Stent within standard clinical routine for the treatment of patients with symptomatic non-stenotic carotid disease (SyNC) and with high-risk plaque features…
- Conditions
- Carotid Artery Disease, Symptomatic Carotid Artery Stenosis, Carotid Artery Stenting, Carotid Plaque Imaging
- Trial name
- CARESTAR (NCT07166731)
- Where
- Germany
- Volunteers
- 536 people
- Sponsor
- Acandis GmbH
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Dementia, Dementia, Vascular
Advanced Cognitive Stimulation Therapy Hong Kong (ACST-HK)
This study is a feasibility randomized controlled trial (RCT) for an evidence-based intervention for people with moderate to severe dementia in Hong Kong.
- Conditions
- Dementia, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies
- Trial name
- NCT04555629
- Testing
- Advanced Cognitive Stimulation Therapy Hong Kong
- Volunteers
- 32 people
- Sponsor
- University College, London
Atherosclerotic Cardiovascular Disease
In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease
Study CKJX839B1FR01 in an In silico trial to predict the efficacy of Inclisiran therapy on major adverse cardiovascular events (MACE) and cardiovascular (CV) death in virtual patients with atherosclerotic cardiovascular disease…
- Trial name
- SIRIUS (NCT05974345)
- Testing
- Inclisiran sodium, Ezetimibe, Evolocumab
- Where
- France
- Volunteers
- 204,691 people
- Sponsor
- Novartis Pharmaceuticals
Acute Ischemic Stroke
REVascularization In Large VEssel Occlusion for Acute Ischemic Stroke
The objective of this study is to evaluate the safety and effectiveness of the SOFIA Flow 88 Aspiration Catheter for treatment of acute ischemic stroke.
- Trial name
- REVIVE (NCT07216170)
- Testing
- SOFIA Flow 88 Aspiration Catheter
- Volunteers
- 200 people
- Sponsor
- Microvention-Terumo, Inc.
Stroke, Ischemic
Regional Strategy for Transfer for Mechanical Thrombectomy
A mono-centre observational study with the aim of compare clinical outcome at 3 month on patients admitted with recent cerebral infarct and intracranial large vessel occlusion in the anterior circulation who are eligible for…
- Conditions
- Stroke, Ischemic, Large Vessel Occlusion
- Trial name
- START (NCT04046757)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
Coronary Stenosis, Carotid Stenosis
Detection of Coronary Stenosis With Intravenous Microbubbles
To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.
- Conditions
- Coronary Stenosis, Carotid Stenosis, Myocardial Reperfusion
- Trial name
- NCT00580580
- Testing
- Optison, Definity, PESDA
- Sponsor
- University of Nebraska
Carotid Artery Disease, Carotid Artery Stenoses
Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery
Currently, over 400,000 reconstructive surgeries on carotid arteries are performed annually worldwide, including carotid endarterectomy (CEA) and carotid stenting.
- Trial name
- NCT07200180
- Testing
- Аrgon-oxygen breathing mixture, Nitrogen-oxygen breathing mixture
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Negovsky Reanimatology Research Institute
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