Clinical trials: Occlusion, Cerebrovascular
Vascular Dementia
Rivastigmine Capsules in Patients With Probable Vascular Dementia
The goal of this research study is to evaluate, in the open-label extension phase, the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable…
- Trial name
- NCT00130338
- Testing
- Rivastigmine
- Volunteers
- 521 people
- Sponsor
- Novartis
Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
Protective Effect of EPA on Cardiovascular Events
The purpose of this study was to test the hypothesis that the long-term use of highly (>98%) purified EPA, in addition to HMG-CoA reductase inhibitor (statin), would be more effective than statin alone in preventing…
- Trial name
- NCT00231738
- Testing
- Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
- Where
- Japan
- Volunteers
- 18,000 people
- Sponsor
- Kobe University
Ischemic Stroke
Cerebellar Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- CIV-ABAO (NCT04611178)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Carotid Artery Diseases, Aortic Diseases
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
The purpose of this registry is to evaluate the long-term safety and performance of Intervascular Vascular Grafts and Patches (Intergard Standard, Hemashield, Intergard Silver, Intergard Synergy) for bypass, repair or replacement…
- Conditions
- Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
- Trial name
- NCT07322913
- Testing
- Intergard Standard - Collagen Coated Vascular Grafts and Patches, Hemashield - Collagen Coated Vascular Grafts and Patches, Intergard Silver - Antimicrobial Collagen Coated Vascular Grafts and Patches
- Where
- 5 sites in United States, Belgium and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Intervascular
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm
Stellate Ganglion Block in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
To investigate whether the stellate ganglion block is helpful in relieving cerebral vasospasm during aneurysmal coil embolism surgery. The effect was assessed by Transcranial Doppler (TCD).
- Trial name
- NCT04512859
- Testing
- Stellate Ganglion Block
- Volunteers
- 160 people
- Sponsor
- Beijing Tiantan Hospital
Plaque, Atherosclerotic, Carotid Artery Plaque
Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk
Stroke is a leading cause of death and disability in the United States and around the world. The goal of this work is to develop and test a noninvasive ultrasound-based imaging technology to better identify patients at high risk…
- Conditions
- Plaque, Atherosclerotic, Carotid Artery Plaque, Carotid Stenosis
- Trial name
- NCT04063709
- Testing
- Acoustic Radiation Force Impulse (ARFI) ultrasound
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Carotid Stenosis
Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis
Purpose of this study: Primary: Comparison of cardiovascular mortality and morbidity which includes cardiac and neurological morbidity (TIA and CVA) in the two invasive treatments of asymptomatic carotid artery stenosis…
- Trial name
- NCT00772278
- Testing
- carotid artery stenting, carotid endarterectomy
- Where
- Israel
- Volunteers
- 137 people
- Sponsor
- Carmel Medical Center
Acute Ischemic Stroke
Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions
The goal of this clinical trials is to demonstrate the safety and effectiveness for the RapidPulseTM Aspiration System in patients experiencing acute ischemic stroke within 8 hours of symptom onset or last seen normal.
- Trial name
- TURBO (NCT06029491)
- Testing
- RapidPulseTM Aspiration System
- Where
- 30 sites in United States, France and 2 more
- Volunteers
- 170 people
- Sponsor
- RapidPulse, Inc
Atherosclerosis, Cardiovascular Diseases
Multinational Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA)
To foster collaboration between the World Health Organization MONICA Project and the NHLBI Study of Atherosclerosis Risk in Communities (ARIC).
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease
- Trial name
- NCT00005678
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Subdural Hematoma, Anesthesia
Nerve Block Anesthesia Combined With Sedative Anesthesia Versus General Anesthesia in Surgery for CSDH
A prospective, multicenter, randomized controlled trial is designed to evaluate the safety of nerve block anesthesia combined with sedative anesthesia versus general anesthesia during burr hole craniostomy with drainage for…
- Trial name
- NCT05888389
- Testing
- Cranial Nerve Block Anesthesia Combined With Sedative Anesthesia, General Anesthesia
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Intracranial Atherosclerosis
Treatment Targets for Inflamed Intracranial Atherosclerosis on Vessel Wall MRI
Intracranial atherosclerosis (ICAS) accounts for 10 to 40%, depending on ethnicity, of the 700,000 ischemic strokes in the United States every year.
- Trial name
- NCT03084523
- Testing
- Ferumoxytol Injectable Product
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Ischemic Stroke
Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients with Large Vessel Occlusion
Patients presenting to the emergency department with an acute ischemic stroke due to a large vessel occlusion eligible for thrombectomy and target mismatch on computed tomography perfusion imaging within 24 hours of onset will be…
- Trial name
- ETERNAL-LVO (NCT04454788)
- Testing
- Tenecteplase, Standard Care (which may include intravenous Alteplase)
- Where
- 7 sites in Australia
- Volunteers
- 242 people
- Sponsor
- University of Melbourne
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Carotid Artery Stenosis
Imaging of Unstable Carotid Plaque in Patient Referred to Endarterectomy
This study will assess unstable plaque imaging features by using high resolution MR imaging and Sodium Fluoride F-18 PET. This is a comparative study between symptomatic and asymptomatic patient referred to carotid…
- Trial name
- CAROTEP (NCT03353103)
- Testing
- Sodium fluoride F-18 PET imaging
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Alzheimer's Disease, Dementia
Blood Gene Expression Signature in Patients Diagnosed With Probable Alzheimer's Disease Compared to Patients Suffering From Other Types of Dementia
The objective of the study is to define the performance of blood-based signatures for Alzheimer's Disease (AD) in different patients populations including AD, non-AD dementia, and non-demented controls.
- Trial name
- NCT00880347
- Testing
- Blood sampling
- Where
- 21 sites in France
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Exonhit
Microvascular Angina, Angina Pectoris
Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) Trial
Anginal symptoms due to ischaemia with no obstructive coronary arteries (INOCA) is a common clinical problem, however, diagnosis and onward management is heterogeneous, and prognosis is affected.
- Conditions
- Microvascular Angina, Angina Pectoris, Angina, Stable, Non-Obstructive Coronary Atherosclerosis
- Trial name
- CorCMR (NCT04805814)
- Testing
- CMR results disclosed, CMR performed but results not disclosed
- Where
- 3 sites in United Kingdom
- Volunteers
- 280 people
- Sponsor
- NHS National Waiting Times Centre Board
Carotid Artery Stenosis, Superficial Femoral Artery Stenosis
VFI in Healthy Vessels
There is a wealth of evidence implicating the important role of blood flow throughout all stages of the process of atherogenesis.
- Trial name
- NCT05451485
- Testing
- Blood speckle tracking, Ultrasound particle Imaging Velocimetry, 4D flow MRI
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Atherosclerosis, Coronary Artery Disease
Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution
The main goal of this clinical trial is to evaluate the feasibility of conducting a large-scale clinical trial testing a program containing several aspects for reducing the effects of air pollution on cardiovascular health (which…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Peripheral Arterial Disease, Ischemic Stroke
- Trial name
- NCT06261606
- Testing
- Hybrid strategy
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Parham Sadeghipour
Cerebral Aneurysm
A Medical Device to Treat Brain Aneurysms
An aneurysm is a bulge in a blood vessel caused by a weakness in the blood vessel wall, usually where it branches. As blood passes through the weakened blood vessel, the blood pressure causes a small area to bulge outwards like a…
- Trial name
- NCT04963933
- Testing
- Nautilus endovascular device
- Where
- 2 sites in Bulgaria, Latvia
- Volunteers
- 30 people
- Sponsor
- EndoStream Medical
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