Clinical trials: Occlusion Carotid
Atherosclerotic Disease, Carotid
SmartRisk Stroke Prediction by MRI of Carotid Disease
Atherosclerotic plaque at the carotid artery bifurcation is a major source of stroke. The purpose of this investigation is to determine the ability of the SmartRisk software module to predict stroke or stroke-related events due…
- Trial name
- SmartRisk (NCT00860184)
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- VPDiagnostics
Aortic Disorders, Carotid Disease
A Multicenter Study of Iomeron®-400 Used With Multi-detector Computed Tomography Angiography (MDCTA)
This is a Phase IV multicenter, open-label study and is being implemented in order to assess diagnostic image quality of MDCTA in subjects undergoing computed tomography angiography (CTA) of the thoraco-abdominal aorta, and the…
- Conditions
- Aortic Disorders, Carotid Disease, Pulmonary Disease, Peripheral Artery Disease
- Trial name
- Iomeron®-400 (NCT02596048)
- Testing
- Iomeron
- Where
- 5 sites in China
- Volunteers
- 224 people
- Sponsor
- Bracco Diagnostics, Inc
Brain Tumor, Stroke, Acute
Safety and Feasibility of the Infinity Catheter for Radial Access
The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial…
- Conditions
- Brain Tumor, Stroke, Acute, Brain Aneurysm, Intracranial Arteriovenous Malformations
- Trial name
- NCT04553549
- Testing
- Transradial approach
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Peripheral Chemosensitivity
The Breath-2 Trial
This is a randomized, cross over, experimental trial in which carotid body function will be evaluated in 35 healthy subjects during partial muscle relaxation and after recovery from muscle relaxation
- Trial name
- NCT05149872
- Testing
- Muscle relaxation, Reversal
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Carotid Artery Disease, Stroke
Effects of Cerebral Protection With Filters vs. Flow Reversal on Cerebral Embolization After Carotid Artery Stenting
Carotid artery stenting (CAS) with cerebral embolic protection is the preferred treatment for narrowing of the carotid arteries in patients at high risk for open surgery.
- Trial name
- NCT01414387
- Testing
- Carotid filter, Carotid reversal of flow
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Dallas VA Medical Center
Carotid Artery Plaque
Carotid Plaque Assessment Using 18Fluorine (18F) -Sodium Fluoride Positron Emission Tomography (PET) /MR
Carotid plaque can lead to ischemic stroke. Treatment of asymptomatic carotid plaque, based on degree stenosis, is still controversial.
- Trial name
- CARTIS (NCT02726984)
- Testing
- 18F-sodium fluoride PET/MR
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Dyslipidemias, Atherosclerosis
Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
This is a randomized controlled study to assess the effect of atorvastatin and omega 3 combination therapy compared with atorvastatin and ezetimibe combination therapy in Korean T2DM patients with asymptomatic atherosclerosis.
- Conditions
- Dyslipidemias, Atherosclerosis, Diabetes Mellitus, Type 2
- Trial name
- NCT05365438
- Testing
- Omega 3-Atorvastatin, Atorvastatin-Ezetimibe
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Seoul National University Bundang Hospital
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery
Since stroke and myocardial ischemia are major causes of perioperative morbidity and mortality associated with carotid endarterectomy, monitoring the brain and ensuring the best hemodynamic stability are important goals of…
- Trial name
- NCT02450734
- Testing
- Ultrasound-guided intermediate cervical plexus block
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Mutualiste Montsouris
Fibromuscular Dysplasia
Cohort Follow-up of Patients With Renal or Craniocervical Fibromuscular Dysplasia
PROFILE is a cohort study evaluating the progression of fibromuscular dysplasia lesions. This study is the prospective dimension of ARCADIA registry (ClinicalTrials.gov Identifier: NCT02884141), which aims to document phenotypic…
- Trial name
- PROFILE (NCT02961868)
- Testing
- Abdominal and supra-aortic trunks vascular imaging, Blood sampling (genetic), Blood sampling (biomarkers)
- Where
- 17 sites in Belgium, France
- Volunteers
- 340 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carotid Artery Disease, Carotid Artery Stenoses
Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery
Currently, over 400,000 reconstructive surgeries on carotid arteries are performed annually worldwide, including carotid endarterectomy (CEA) and carotid stenting.
- Trial name
- NCT07200180
- Testing
- Аrgon-oxygen breathing mixture, Nitrogen-oxygen breathing mixture
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Negovsky Reanimatology Research Institute
Carotid Stenosis
Insulin Resistance in Patients After Carotid Revascularization
The main purpose of this study is to study the phenomenon of insulin resistance in patients after carotid revascularization surgery through population-based, randomized, double-blind, placebo-controlled trial.
- Trial name
- NCT03419767
- Testing
- Melatonin, blank
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Carotid Artery Stenosis, Carotid Artery Diseases
Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets for Cerebral Protection During Carotid Angioplasty
- Trial name
- NCT06959628
- Testing
- Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Coronary Artery Disease, Coronary Heart Disease
Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
The primary purpose of this study is to test the effect and safety of once daily ABT-335 on the thickness of the lining of the carotid artery (a blood vessel to the brain) in patients with abnormal blood lipids who have optimal…
- Conditions
- Coronary Artery Disease, Coronary Heart Disease, Dyslipidemia
- Trial name
- FIRST (NCT00616772)
- Testing
- ABT-335, Atorvastatin
- Where
- 124 sites in United States
- Volunteers
- 682 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Carotid Stenosis
Carotid Region Calcifications and Orthopantomogram
Observational study.
- Trial name
- ADCACO (NCT03936881)
- Where
- France
- Volunteers
- 401 people
- Sponsor
- Rennes University Hospital
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Carotid Stenosis, Carotid Artery Plaque
CARotid Mri of Atherosclerosis
In the entire world most people die from cardiovascular disease. Death is primarily from myocardial infarction (MI) and stroke which are most often caused by rupture of atherosclerotic plaques. Patients with high-grade, i.e.
- Conditions
- Carotid Stenosis, Carotid Artery Plaque, Carotid Atherosclerosis
- Trial name
- CARMA (NCT04835571)
- Testing
- Optimization of cardiovascular risk management
- Volunteers
- 52 people
- Sponsor
- Linkoeping University
Stroke, Stenosis
Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic…
- Trial name
- NCT00126139
- Testing
- Abciximab
- Where
- 5 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Carotid Stenosis
Noninvasive Evaluation for Carotid Artery Stenosis: The Carotid Stenotic Scan
The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid duplex ultrasound study.
- Trial name
- CSS (NCT04057183)
- Testing
- Carotid Stenotic Scan
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Phillip J Bendick
Cerebrovascular Occlusion, Collateral Blood Circulation
The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion
Stroke is the first leading cause of death in China, and is responsible for almost 22.4% of deaths. In approximately 80% of cases stroke is ischaemic, i.e.
- Conditions
- Cerebrovascular Occlusion, Collateral Blood Circulation, Anterior Cerebral Circulation Infarction
- Trial name
- INCIMO (NCT02594995)
- Testing
- NBP
- Where
- China
- Volunteers
- 311 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine