Clinical trials: Occlusion of Artery
Coronary Artery Disease, Percutaneous Coronary Intervention
Prasugrel Versus Double Dose Clopidogrel to Treat Clopidogrel Low-responsiveness After PCI
All patients undergoing elective or sub-acute PCI are screened by MULTIPLATE test for clopidogrel low-responsiveness after receiving 600 mg clopidogrel the day before. A cut off value has previously been established.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndromes
- Trial name
- TAILOR (NCT01135667)
- Testing
- clopidogrel, Prasugrel 10 mg
- Where
- Denmark
- Volunteers
- 106 people
- Sponsor
- Lene Holmvang
Coronary Artery Disease
Influence of Different Forms of Exercise Training in Patients With Coronary Artery Disease
The aim of the study is to compare the effect of water-based and land-based exercise training, and usual care (no exercise training) in patient with coronary artery disease, on exercise capacity, vascular function, arrhythmogenic…
- Trial name
- NCT02831829
- Testing
- water-based exercise training, land-based exercise training
- Where
- 2 sites in Slovenia
- Volunteers
- 90 people
- Sponsor
- University Medical Centre Ljubljana
Coronary Artery Disease, Acute Kidney Injury
Use of Flozins (Empagliflozin/Dapagliflozin) for Prevention of AKI
All consecutive patients hospitalized from 01.01.2020 to 30.09.2025 who underwent coronary angiography or PCI will be eligible for inclusion.
- Conditions
- Coronary Artery Disease, Acute Kidney Injury, Contrast-Induced Acute Kidney Injury, Percutaneous Coronary Intervention
- Trial name
- FLORENCE (NCT07231939)
- Testing
- Flozin
- Where
- Poland
- Volunteers
- 4,000 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Aorta Disease, Peripheral Artery Disease
Asan Aorta and Peripheral Registry
The purpose of this study is to evaluate the clinical results of patients who received revascularization of the aorta and peripheral artery at Asan Medical Center.
- Trial name
- PTA (NCT06022653)
- Testing
- Treatment
- Where
- South Korea
- Volunteers
- 6,000 people
- Sponsor
- Asan Medical Center
Coronary Artery Disease
Cardiac Pathologies in Standard Thoracic CT Imaging
Modern high-end CT scanners with faster scan acquisition times now allow for routine assessment of cardiac pathologies, which could result in numerous incidental cardiac findings on standard thoracic CT angiography (CTA) scans.
- Trial name
- CaPaCT (NCT02904239)
- Where
- Netherlands
- Volunteers
- 221 people
- Sponsor
- Maastricht University Medical Center
Peripheral Vascular Diseases
Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a disease in which fatty build-up, or "plaque," accumulates in the peripheral arteries. People with PAD often experience leg pain while walking due to reduced blood flow to the legs.
- Trial name
- NCT00520312
- Where
- United States
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Disease
Treatment of Primary Coronary Artery Vascular Lesions With Biolimus Coated Coronary Balloon Dilation Catheter
The purpose of the study was to further evaluate the long-term safety and efficacy of the Biolimus Coated Coronary Artery Balloon Dilation Catheter in the real world.
- Trial name
- NCT06385067
- Testing
- Biolimus Coated Coronary Artery Balloon Dilation Catheter
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- JW Medical Systems Ltd
Coronary Artery Disease, Edema
The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients.
The organ dysfunction following cardiopulmonary bypass (CPB) occurs frequently in cardiac surgery patients. Systemic inflammatory response initiated by CPB through releasing of several mediators lead to altered endothelial…
- Trial name
- ESHHS (NCT01675453)
- Testing
- 7.2% NaCl plus 6% hydroxyethyl starch 200/0.5, 0.9% NaCl
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Disease, Coronary Artery Disease
SPIRIT V: Post-marketing Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in Europe
The purpose of this Clinical Evaluation is a continuation in the assessment of the performance of the XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® EECSS) in the treatment of patients with de novo coronary artery…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- SPIRIT V (NCT00402272)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent
- Where
- 93 sites in Austria, Belgium and 21 more
- Volunteers
- 2,700 people
- Sponsor
- Abbott Medical Devices
Carotid Artery Stenosis
Neuroimaging Correlates of Memory Decline Following Carotid Interventions
Carotid revascularization can significantly reduce the risk of stroke in patients with severe carotid stenosis; however, it has been associated with cognitive decline in 25% of the older adults who undergo the procedure.
- Trial name
- NCT02006095
- Testing
- Magnetic resonance imaging, Neuropsychological testing
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rheumatoid Arthritis, Coronary Artery Disease
Effects of Interleukin-1 Inhibition on Vascular and Left Ventricular Function in Rheumatoid Arthritis Patients With Coronary Artery Disease
Inhibition of interleukin-1 (IL-1) activity in patients with RA without CAD ameliorates vascular and LV function. Moreover, data from species shows beneficial effect of this treatment on LV function after experimental myocardial…
- Conditions
- Rheumatoid Arthritis, Coronary Artery Disease, Inflammation
- Trial name
- NCT01566201
- Testing
- anakinra
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Athens
Peripheral Arterial Disease
Sonodynamic Therapy in the Treatment of Perivascular Adipose Tissue on Patients With PAD and Claudication
The purpose of this trial is to evaluate the safety and efficacy of sonodynamic therapy (SDT) in reducing the inflammation of perivascular adipose tissue and increasing peak walking time (PWT) among peripheral artery disease…
- Trial name
- NCT03967730
- Testing
- Sonodynamic therapy(SDT)
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Ischemic Heart Disease, Coronary Artery Disease
Prospective Registry of Patients Over 75 Years Old Treated With Xience Sierra Stents. Sierra 75 Study
This prospective registry is intended to evaluate the safety and efficacy of the XIENCE Sierra stent.
- Trial name
- SIERRA 75 (NCT03567733)
- Testing
- XIENCE Sierra
- Where
- 44 sites in Portugal, Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundación EPIC
Coronary Artery Disease
Initial Evaluation of Vascudyne Coronary Artery Bypass Conduit
The Vascudyne Coronary Artery Bypass Study (VCAB-1) is an initial safety and feasibility study of the Vascudyne, Inc. Coronary Artery Bypass Conduit (CAB A) for bypass of stenosed native coronary arteries in patients undergoing…
- Trial name
- VCAB-1 (NCT06434935)
- Testing
- CABA
- Where
- Paraguay
- Volunteers
- 5 people
- Sponsor
- Vascudyne, Inc.
Coronary Artery Disease
The Impact of Remimazolam for Postoperative Sedation on the Left Ventricular Systolic Performance in Cardiac Surgery
This study analyzes the impact of intraoperative Remimazolam infusion for postoperative sedation on the left ventricular global longitude strain (LV-GLS) patients undergoing cardiac surgery
- Trial name
- NCT05041725
- Testing
- Remimazolam Injection [Byfavo]
- Volunteers
- 15 people
- Sponsor
- Konkuk University Medical Center
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Coronary Artery Disease, Calcification
Post-Marketing Clinical Study of High-Pressure Cutting Balloon
This study is designed as a prospective, multicenter, 1:1 randomized controlled trial. It plans to enroll 280 patients with moderate-to-severe calcified coronary lesions who are candidates for IVUS-guided DES implantation.
- Trial name
- NCT07835178
- Testing
- High pressure cutting balloon, Non-cutting balloon
- Where
- China
- Volunteers
- 280 people
- Sponsor
- BrosMed Medical Co., Ltd
Computed Tomography Angiography, Coronary Artery Disease
Techniques and Pitfalls of Multi-Slice CT Coronary Angiography
The goal of this study is to describe the techniques for coronary multi-slice CT angiography and to illustrate the spectrum of artifacts that can simulate coronary artery stenosis and lead to non-assessable segments using 128…
- Trial name
- NCT05729490
- Testing
- Coronary computed tomography angiography
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Peripheral Arterial Disease
Telerehabilitation in Patients With Peripheral Arterial Disease
This prospective longitudinal study evaluated the feasibility, adherence, and clinical and functional effects of a 6-month home-based telerehabilitation program in patients with peripheral arterial disease of the lower limbs.
- Trial name
- PAD_TR (NCT07825168)
- Testing
- Home-based telerehabilitation
- Where
- Romania
- Volunteers
- 42 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Cardiovascular Diseases, Coronary Arteriosclerosis
Long-Term Effects of Subclinical CAD on Cardiac Function
To assess changes in coronary calcium measured by electron beam computed tomography (EBCT) as a predictor of coronary heart disease (CHD) events.
- Conditions
- Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases
- Trial name
- NCT00006497
- Sponsor
- University of California, Irvine
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