Clinical trials: Occlusion of Artery
Coronary Artery Disease
Breath-hold Cardiac Hybrid SPECT/CCTA
This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.
- Trial name
- NCT02469051
- Testing
- Breathhold SPECT-MPI, Standard freebreathing SPECT-MPI, Coronary CT angiography
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure
Reliability of 3D angio QFR functional evaluation of all non culprit lesions >50% in STEMI patients during first acute procedure
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease
- Trial name
- NCT02998853
- Testing
- QFR measurement by dedicated workstation on xrays angio selected runs
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Sant'Anna e San Sebastiano
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD)
VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN)
The goal of this study is to understand and compare an alternative model of care in comparison to the usual model of care in include male and female participants ≥18 years of age with a history of ASCVD (hear and blood vessels…
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD), Cerebrovascular Disease, Peripheral Arterial Disease (PAD)
- Trial name
- v-ASCERTAIN (NCT05834673)
- Testing
- SMS messages, Telephone-based support calls, GP Education
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Monash University
Intracranial Aneurysm, Pipeline Embolization Device
Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China
Pipeline TM embolization device launched to China in 2014, and has been widely used to treat large width IA. Therefore, it is necessary to collect and analysis the clinical data to evaluate effectiveness and safety of its usage…
- Trial name
- PLUS (NCT03831672)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Aortic Valve Stenosis
Non-Contrast Magnetic Resonance Angiography Assessment of Patients Referred for Transcatheter Aortic Valve Implantation
The overall objective of this proposal is to examine the feasibility and accuracy of non-contrast magnetic resonance angiography (MRA) to comprehensively evaluate individuals referred for transcatheter aortic valve implantation…
- Trial name
- NCT02007967
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Coronary Arteriosclerosis
Study of the Effect of omega3 on Biomarkers of Cardiac Necrosis (CKMB and Troponin I) and Inflammation Marker (CRP) After Elective Percutaneous Coronary Intervention (PCI)
The purpose of this study is to investigate the effect of omega 3 on biomarkers of cardiac necrosis(CKMB and troponin I) and inflammation marker CRP.
- Trial name
- NCT01521845
- Testing
- omega 3
- Where
- Iran
- Volunteers
- 104 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Angina Pectoris, Stable
Effects of Ivabradine on Residual Myocardial Ischemia After PCI
This is a randomized pharmacological study evaluating the effects of ivabradine in patients with residual angina after PCI. The role of ivabradine in patients with angina, without systolic dysfunction, is not yet clear.
- Trial name
- NCT03866395
- Testing
- Ivabradine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Azienda Policlinico Umberto I
Aortic Valve Disease, Coronary Artery Disease
Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease
Study Objectives/Specific Aims Overall Goal: To study the outcomes of patients undergoing TAVI, their subsequent results and complications.
- Trial name
- NCT04525339
- Testing
- TAVI and Off pump CABG
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Coronary Artery Disease
Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Trial
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is estimated based on two angiographic projections.
- Trial name
- NCT03729739
- Testing
- QFR-based diagnostic strategy, FFR-based diagnostic strategy
- Where
- 35 sites in Denmark, France and 9 more
- Volunteers
- 2,001 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Heart Disease (CHD)
Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction
A Phase IIB Parallel group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants with a Prior Myocardial Infarction.
- Trial name
- GOLDILOX (NCT04610892)
- Testing
- MEDI6570
- Where
- 84 sites in United States, Australia and 9 more
- Volunteers
- 423 people
- Sponsor
- AstraZeneca
Intracranial Atherosclerosis
A Study of Implantation of CRENEOUS ENTERPRISE 2 Intracranial Stent in Participants With Severe Symptomatic Intracranial Atherosclerotic Stenosis
The purpose of this study is to evaluate the safety and effectiveness of CERENOVUS ENTERPRISE 2 intracranial stent implantation in treatment of participants with severe symptomatic intracranial atherosclerotic stenosis.
- Trial name
- NCT05316311
- Testing
- CERENOVUS ENTERPRISE 2 Intracranial Stent
- Where
- 14 sites in China
- Volunteers
- 194 people
- Sponsor
- Medos International SARL
Coronary Artery Disease
Alternative Risk Markers in Coronary Artery Disease (ARMCAD)
Estimating the risk of future cardiovascular events such as death, stroke and myocardial infarction using traditional risk factors (such as age, gender, smoking, diabetes, hyperlipidaemia and hypertension) is well accepted in…
- Trial name
- NCT00403351
- Where
- 4 sites in Australia
- Volunteers
- 665 people
- Sponsor
- Monash University
Iron Deficiency Anemia, Coronary Artery Disease
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
The goal of this observational study is to learn how well Ferretab® comp. works and how safe it is for adults with iron deficiency anemia and cardiovascular disease who are receiving treatment as part of their usual medical care.
- Conditions
- Iron Deficiency Anemia, Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PROMETHEUS (NCT07753031)
- Where
- 5 sites in Russia
- Volunteers
- 389 people
- Sponsor
- Alcea
Coronary Artery Disease, Atherosclerosis
Evaluation of a Diagnostic Software for Coronary Artery Disease Using Retrospective CCTA Data (CODEX-1 Study)
The CODEX-1 study is a multicenter retrospective observational study designed to assess the diagnostic performance of a novel software application for coronary artery disease (CAD) evaluation.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Myocardial Ischemia
- Trial name
- CODEX1 (NCT06977295)
- Testing
- Diagnostic Software Application for CAD Assessment
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
Hypercholesterolemia
Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)
The purpose of this 24 week study is to compare the effectiveness and safety of different doses of Niacin ER/Simvastatin (NS) in subjects with elevated fat levels in their blood (dyslipidemia).
- Trial name
- NCT00080275
- Testing
- Niacin Extended-Release and simvastatin Tablets
- Volunteers
- 600 people
- Sponsor
- Kos Pharmaceuticals
Coronary Artery Disease, Risk Factor
Asan Medical Center CCTA Registry
A total of 9269 adults who received CCTA scans for coronary disease evaluation during a general medical checkup at the Health Screening and Promotion Center in Asan Medical Center, Seoul, Korea between January 2007 and December…
- Conditions
- Coronary Artery Disease, Risk Factor, Computed Tomography
- Trial name
- NCT06036901
- Testing
- Coronary CT
- Volunteers
- 6,343 people, healthy volunteers welcome
- Sponsor
- CardioVascular Research Foundation, Korea
Peripheral Arterial Disease, Diabetes Mellitus
Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease
To compare the screening capabilities of the BlueDop Vascular Expert (BVE) and ankle brachial index (ABI) in peripheral arterial disease for all-comer patients and those with diagnosed diabetes mellitus.
- Trial name
- NCT06436001
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dakota Vascular
Peripheral Artery Disease, Peripheral Vascular Disease
Investigational Device Exemption Study to Determine the Safety and Efficacy of the Astron and Pulsar Stents
The objective of this study is to separately demonstrate the safety and efficacy of BIOTRONIK's Astron and Pulsar stents. The Pulsar stent will be used for the treatment of femoro-popliteal lesions, located in the native…
- Trial name
- BIOFLEX-I (NCT01319812)
- Testing
- Astron Stents, Pulsar Stents
- Where
- 35 sites in United States, Canada
- Volunteers
- 463 people
- Sponsor
- Biotronik, Inc.
Metabolic Disease, Obesity
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Background: Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels.
- Conditions
- Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy
- Trial name
- NCT01143454
- Testing
- NSR IDE-MRI: Research pulse sequences
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease, Myocardial Infarction
Mi-RNAs and Specificity of Hs-TnT in Symptomatic ED Patients
Biomarkers play a key role in the diagnostic workup of patients presenting to an emergency department (ED). European and American guidelines recommend cardiac Troponin (T or I) as the biomarker gold standard for the diagnosis of…
- Trial name
- NCT02116153
- Sponsor
- University Hospital Heidelberg
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