Clinical trials: Occlusion of Artery
Myocardial Infarction, Stable Angina
Readiness for Behavior Change After a Heart Attack
The purpose of this study is to test if an early appointment (within 10 days) when compared to a standard appointment (5 weeks) will affect attendance at the Cardiac Rehabilitation orientation and subsequent enrollment into…
- Conditions
- Myocardial Infarction, Stable Angina, Coronary Artery Disease
- Trial name
- ENROLL (NCT01596036)
- Testing
- Early appointment (within 10 days), Routine referral (at 5 weeks)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Coronary Artery Disease
CorVad Percutaneous Ventricular Assist System Study
This study aims to evaluate the safety and effectiveness of the CorVad Percutaneous Ventricular Assist System for short-term ventricular support during high-risk percutaneous coronary intervention (HRPCI) in non-emergent…
- Trial name
- NCT06198998
- Testing
- CorVad Percutaneous Ventricular Assist System
- Where
- 12 sites in China
- Volunteers
- 120 people
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
Circulation, Collateral, Coronary Artery Disease
Effect of Permanent Right Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply
Coronary artery disease and the benefit of bypasses: Despite considerable advances in medicine, cardiovascular diseases remain the number one cause of death globally, primarily consequence of myocardial infarction (MI).
- Conditions
- Circulation, Collateral, Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, Ischemia
- Trial name
- IMAOR (NCT03950947)
- Testing
- Amplatzer vascular plug
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Myocardial Infarction, Acute, Coronary Artery Disease
Evaluation of a Modified Anti-Platelet Therapy Associated With Low-dose DES Firehawk in Acute Myocardial Infarction Patients Treated With Complete Revascularization Strategy
The study aims to evaluate a modified antiplatelet therapy associated with Firehawk low-dose rapamycin DES in acute myocardial infarction patients treated with complete revascularization strategy.
- Trial name
- TARGET-FIRST (NCT04753749)
- Testing
- Shortened DAPT followed by P2Y12 inhibitor monotherapy (cessation of aspirin), Standard DAPT
- Where
- 40 sites in Austria, France and 4 more
- Volunteers
- 2,248 people
- Sponsor
- MicroPort CRM
Atherosclerosis, Atheroscleroses, Coronary
Detection of Coronary Artery Calcifications by Whole Blood Transcriptome Analyzed by Artificial InTelligence Algorithms
The goal of this observational study is to determine the diagnostic accuracy of peripheral whole blood transcriptomes analyzed by an artificial intelligence algorithm to detect the presence and extent of coronary calcification in…
- Conditions
- Atherosclerosis, Atheroscleroses, Coronary, Atherosclerotic Plaque
- Trial name
- CAC-TRAIT (NCT05619042)
- Where
- Argentina
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Santiago Gabriel Miriuka
Coronary Artery Disease
BFPET for Regional Myocardial Perfusion Imaging
BFPET will be evaluated as a diagnostic PET agent for assessing myocardial perfusion in subjects with known or suspected coronary artery disease (CAD) as compared to standard nuclear myocardial perfusion imaging (MPI).
- Trial name
- NCT02252783
- Testing
- BFPET
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Fluoropharma, Inc.
Superior Mesenteric Artery Syndrome
Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population
Multicenter, prospective, observational research project on children aged from 10 to 15 years old undergoing abdominal ultrasound examinations during routine clinical practice.
- Trial name
- NCT04515251
- Testing
- Ultrasound measurements
- Where
- 2 sites in Switzerland
- Volunteers
- 289 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Systemic Sclerosis
Investigation of Coronary and Pulmonary Circulatory Parameters in Systemic Sclerosis
Aim: Determination of frequency and nature of coronary involvement (including epicardial and microvascular) among scleroderma patients referred for right heart catheterization.
- Trial name
- NCT00843102
- Where
- Hungary
- Volunteers
- 120 people
- Sponsor
- University of Pecs
Atherosclerotic Cardiovascular Disease, Cardiovascular Disease
Intima-Medial Thickness Guidance of Primary Prevention in Relatives of Patients With Early onSet Atherosclerosis
The primary objective of this study is, to instigate a reduction in atherosclerotic burden within the carotid arteries in the intervention group compared to the control group and to demonstrate parallel improvements in…
- Trial name
- IMPRESS (NCT01330602)
- Testing
- IMPRESS intervention
- Where
- 3 sites in Singapore
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Cerebral Atherosclerosis
Clinical Trial of Efficacy and Safety of Divaza for Adjustment of Oxidative Disorders in Patients With Cerebral Atherosclerosis
The purpose of this study is to obtain additional data on efficacy and safety of Divaza for adjustment of oxidative disorders in patients with cerebral atherosclerosis.
- Trial name
- NCT03485495
- Testing
- Divaza
- Where
- 10 sites in Russia
- Volunteers
- 124 people
- Sponsor
- Materia Medica Holding
Moyamoya Disease
The Role of m6A RNA Modification in Moyamoya Disease
The purpose of this study is to detect the change of m6A RNA modification from peripheral blood of patients with moyamoya disease, and to assess the relationship between clinical characteristics.
- Trial name
- NCT04696094
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Congestive Heart Failure, Diabetes
Evaluation of Programs of Coordinated Care and Disease Management
This is a Congressionally mandated study. In the original study, 16 demonstration programs provided care coordination services to beneficiaries with chronic illness in Medicare's fee-for-service program.
- Conditions
- Congestive Heart Failure, Diabetes, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- Coca (NCT00627029)
- Testing
- Care Coordination
- Where
- 15 sites in United States
- Volunteers
- 18,277 people
- Sponsor
- Mathematica Policy Research, Inc.
Type 2 Diabetes, Peripheral Arterial Disease
Liraglutide and Peripheral Artery Disease
STARDUST is an open-label, two-arm randomized controlled trial, aimed at evaluating the effects of liraglutide on peripheral perfusion, as compared with the aggressive treatment of cardio-metabolic risk factors, in people with…
- Trial name
- STARDUST (NCT04881110)
- Testing
- Liraglutide, Control
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Campania Luigi Vanvitelli
Carotid Stenosis
A Randomized Trial of Clinical Decision Making in Asymptomatic Carotid Stenosis
The purpose of this study is to determine patient variables, physician presenter variables, and information variables that might affect clinical decision making in asymptomatic carotid stenosis.
- Trial name
- NCT01315288
- Testing
- One of 6 video presentation by one of 4 presenters
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Coronary Artery Disease, Coronary Artery Bypass
Early Mobilization After CABG Surgery
The goal of this clinical trial is to learn if a structured early exercise program can help patients recover better in people who have just had coronary artery bypass surgery.
- Trial name
- EMAC (NCT07230561)
- Testing
- Structured Early Mobilization Training, Standard Hospital Nursing Care
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Ta-Chung Chao
Coronary Artery Disease, Postoperative Pulmonary Complications
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Pulmonary atelectasis and loss of lung aeration are common complications following cardiac surgery with cardiopulmonary bypass (CPB) and are associated with impaired oxygenation and prolonged mechanical ventilation.
- Conditions
- Coronary Artery Disease, Postoperative Pulmonary Complications, Pulmonary Atelectasis, Postoperative, Diaphragm Dysfunction
- Trial name
- FCV-PCV-DTI-LU (NCT07800741)
- Testing
- Flow-Controlled Ventilation, Pressure-Controlled Ventilation (PCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Percutaneous Coronary Intervention (PCI), Radial Artery Occlusion
Use of Various Types of Introducers in Conventional Radial Access
The purpose of this intervention study is to compare different types of radial introducers used in traditional radial access in terms of the incidence of complications. The main questions it aims to answer are: 1.
- Conditions
- Percutaneous Coronary Intervention (PCI), Radial Artery Occlusion, Radial Artery Spasm
- Trial name
- TIRE (NCT07572422)
- Testing
- catheterization of the radial artery using an classic introducer, catheterization of the radial artery using an introducer with a standard outer diameter and an outer hydrophilic coating, catheterization of the radial artery using an introducer with a reduced outer diameter and an outer hydrophilic coating
- Where
- 2 sites in Russia
- Volunteers
- 3,307 people
- Sponsor
- Pirogov Russian National Research Medical University
Chronic Kidney Diseases
Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging
Conventional contrast-enhanced magnetic resonance imaging is typically performed with extracellular gadolinium chelates, which is often limited in patients with CKD owing to the risk of nephrogenic systemic fibrosis.
- Trial name
- NCT05045872
- Testing
- domestic polysaccharide superparamagnetic iron oxide nanoparticle
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Coronary Artery Disease
Photochemical Tissue Passivation Treatment of Saphenous Vein Grafts in CABG
Early feasibility study of the DurVena Photochemical Tissue Passivation (PTP) device for treatment of saphenous vein grafts in participants undergoing elective coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06150872
- Testing
- DurVena Photochemical Tissue Passivation
- Where
- Uzbekistan
- Volunteers
- 4 people
- Sponsor
- DurVena, Inc.
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
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