Clinical trials: Occlusion of Artery
Coronary Atherosclerosis, Prevention of Heart Disease
CPR Training in 7th Grade Students
This is a prospective study of 7th grade students participating in the CPR Anytime® program. After consent, participants will be asked to complete the program with their parent(s)/legal guardian(s) and encouraged to include other…
- Trial name
- NCT00570609
- Testing
- CPR Anytime education
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Marna Rayl Greenberg
Coronary Artery Disease
A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers
The need exists for alternatives to 99mTc based perfusion radiotracers for cardiac patient management. An alternative radiotracer, I123-CMICE-013, has been developed at the Canadian Molecular Imaging Center of Excellence (C-MICE)…
- Trial name
- CMICE (NCT01558362)
- Testing
- 123I-CMICE-013
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Artery Disease, Stable Angina
BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM
Prospective, multi-center, registry designed to enrol up to 2,000 patients in up to 35 International centers. All patients will receive a BioMatrix AlphaTM stent as per clinical practice and will be followed for 2 years for data…
- Conditions
- Coronary Artery Disease, Stable Angina, Ischemia, Acute Coronary Syndrome
- Trial name
- NCT02871622
- Testing
- BioMatrix AlphaTM
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Biosensors Europe SA
Radial Artery Injury at Wrist and Hand Level, Occlusion of Artery
Intraarterial Nitroglycerin Versus Nicardipine and Radial Artery Occlusion
A total of 600 patients undergoing coronary procedures via transradial access using 6F sheath were randomized at the end of the procedure to receive either 250-µg nicardipine or 500-µg nitroglycerin administered to the radial…
- Conditions
- Radial Artery Injury at Wrist and Hand Level, Occlusion of Artery, Vasodilation
- Trial name
- NONERAO (NCT03622060)
- Testing
- Nitroglycerin
- Where
- Indonesia
- Volunteers
- 600 people
- Sponsor
- Hermina Heart Center Kemayoran
Critical Limb Ischemia
Mesenchymal Stem Cells in Critical Limb Ischemia
This clinical trial aims to study the safety and efficacy of adult mesenchymal stem cells in critical limb ischemia.
- Trial name
- NCT00883870
- Testing
- mesenchymal stem cells, Plasmalyte A
- Where
- 4 sites in India
- Volunteers
- 20 people
- Sponsor
- Stempeutics Research Pvt Ltd
Coronary Artery Disease, Arteriosclerosis
Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension.
- Conditions
- Coronary Artery Disease, Arteriosclerosis, Carotid Stenosis, Thrombosis
- Trial name
- NCT01106573
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Steno-occlusive Disease
Renal MRA Crossover Study Comparing Multihance to Another Contrast Agent
This is an explorative small pilot study comparing two MRA contrast agents, one of which has been on the market for a few years and the other fairly new to the market.
- Trial name
- NCT00415805
- Testing
- Multihance, vasovist
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Bracco Diagnostics, Inc
Coronary Artery Disease, Intestinal Disease
The Role of Gut Leakage Markers and Microbiota Signature in Coronary Artery Disease.
Define a signature of gut microbiota composition and related metabolites in patients with ST-elevation myocardial infarction, non ST-elevation myocardial infarction and chronic coronary disease (CAD).
- Trial name
- GUT-ACS (NCT04605627)
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease
EXCEL-II DES to Treat the Patients With de Novo Coronary Artery Lesions. (CREDIT-III)
The study aims to further assess the safety, efficacy and the performance of its delivery system of the new generation Sirolimus-eluting stent of JWMS up to five years.
- Trial name
- CREDIT-III (NCT02027870)
- Testing
- EXCEL-II biodegradable polymer sirolimus-eluting stent
- Where
- China
- Volunteers
- 625 people
- Sponsor
- JW Medical Systems Ltd
Renal Failure, Coronary Artery Disease
Prevent Cardiac Surgery Associated AKI Trial
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily…
- Conditions
- Renal Failure, Coronary Artery Disease, Surgery, Surgery-Complications
- Trial name
- NCT06620523
- Testing
- CoQ10 1200 mg orally with Glutathione 1000 mg orally
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- George Washington University
Atherosclerosis, Cardiovascular Diseases
Socioeconomic Patterning of Inflammation and Hemostasis - Ancillary to MESA
To investigate how inflammation, hemostasis, and stress may contribute to neighborhood and individual-level socioeconomic differences in cardiovascular risk.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Inflammation
- Trial name
- NCT00091494
- Volunteers
- 1,000 people
- Sponsor
- University of Michigan
Acute Basilar Artery Occlusion, Endovascular Therapy
The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction
This study assesses the efficacy and safety of endovascular therapy in patients with acute basilar artery occlusion with large core infarction within a multicenter, prospective, open-label, blinded endpoint, randomized controlled…
- Conditions
- Acute Basilar Artery Occlusion, Endovascular Therapy, Large Core Infarction
- Trial name
- NCT07333950
- Testing
- Endovascular Recanalization Strategy, Best Medical Management
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Beijing Tiantan Hospital
Coronary Artery Disease
Drug-Coated Balloon in Combination With New Generation Drug-Eluting Stent in the Treatment of Long Diffuse Coronary Artery Disease
An observational study to evaluate safety and efficacy of the hybrid approach DES/DCB in the treatment of long diffuse de novo coronary artery disease
- Trial name
- HYPER II (NCT05650450)
- Testing
- DES+DCB
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Cardiovascular Diseases, Coronary Artery Disease
ISCHEMIA-Chronic Kidney Disease Trial
The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), at least moderate inducible ischemia and advanced chronic kidney disease (CKD; estimated…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- ISCHEMIA-CKD (NCT01985360)
- Testing
- Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention
- Where
- United States
- Volunteers
- 777 people
- Sponsor
- NYU Langone Health
Chest Pain, Coronary Disease
MRI Evaluation of Chest Pain
This study will assess the value of magnetic resonance imaging (MRI) in detecting heart attack and heart attack risk in patients who come to the hospital emergency room because of chest pain.
- Conditions
- Chest Pain, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00001961
- Testing
- MRI
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease, Myocardial Ischemia
Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement
The purpose of this study is to evaluate the safety and effectiveness of the peripheral IV continuous infusion without the insertion of central venous vascular access method in the achievement of steady-state maximal coronary…
- Trial name
- NCT01070420
- Testing
- FFR via central venous line, FFR via peripheral venous line
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Carotid Stenosis
Histological Validation Of Carotid Plaque Composition In Preoperative Imaging
Patients scheduled for carotid endarterectomy undergo preoperative imaging to assess vulnerable plaque. The imaging modalities include (in various combinations at different study sites) 3-dimensional ultrasound, PET/CT imaging…
- Trial name
- NCT01456403
- Testing
- Histological validation
- Where
- 3 sites in Canada
- Volunteers
- 95 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent…
- Trial name
- NCT07308860
- Testing
- FFR-guided PCI, CABG
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Coronary Artery Disease (CAD), Oxidative Stress
Ginger in the Modulation of Inflammatory Cytokines and Oxidative Stress in Patients With Coronary Artery Disease
The study aims to evaluate the effect of ginger supplementation on inflammatory cytokines and markers of oxidative stress in patients with Coronary Artery Disease (CAD).
- Conditions
- Coronary Artery Disease (CAD), Oxidative Stress, Inflammation
- Trial name
- NCT07596979
- Testing
- Ginger
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal Fluminense
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
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