Clinical trials: Occlusion of Artery
Coronary Artery Disease
Efficacy and Saftey Study of 99mTc-ECDG in the Evaluation of Coronary Artery Disease (CAD)
This study will compare how well a new radiolabeled imaging agent ECDG compares to the current testing for coronary artery disease (radiolabeled Sestamibi) during a rest and stress cardiac test as documented from results of a…
- Trial name
- NCT01899833
- Testing
- 99mTc-Sestamibi
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cell>Point LLC
Inflammation, Coronary Artery Disease
Regional Activation of Leukocytes in Coronary Artery Disease
This study aims to evaluate the role of leukocyte activation in coronary artery disease
- Trial name
- REAL-CAD (NCT02376738)
- Where
- 2 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Sint Franciscus Gasthuis
Vascular Dementia
Rivastigmine Capsules in Patients With Probable Vascular Dementia
The goal of this research study is to evaluate, in the open-label extension phase, the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable…
- Trial name
- NCT00130338
- Testing
- Rivastigmine
- Volunteers
- 521 people
- Sponsor
- Novartis
Coronary Artery Disease
Post-Approval Study of PROMUS Element™ in China
The purpose of this study is to compile real-world clinical outcomes data for the PROMUS Element™ and PROMUS Element™ Plus Everolimus-Eluting Coronary Stent System (PROMUS Element and PROMUS Element Plus Stent System) in routine…
- Trial name
- PEChina (NCT01677585)
- Where
- China
- Volunteers
- 2,016 people
- Sponsor
- Boston Scientific Corporation
Acute Kidney Injury, Heart Valve Diseases
Telomere Biology and AKI in Cardiac Surgery
The purpose of this study is to investigate whether biomarkers of cell senescence and aging can predict the development of acute kidney injury following cardiac surgery.
- Conditions
- Acute Kidney Injury, Heart Valve Diseases, Coronary Artery Disease
- Trial name
- NCT02692833
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 254 people
- Sponsor
- Queen Mary University of London
Sleep Apnea, Obstructive, Acute Coronary Syndrome
Effects of Inspiratory Muscles Strengthening Among Coronary Patients on the Sleep Apnea Obstructive Syndrome
Obstructive sleep apnea (OSA) syndrome affects up to 5% of the general population. The prevalence is multiplied by 13 in coronary artery disease (CAD) patients.
- Trial name
- RICAOS (NCT02494648)
- Testing
- POWERbreathe Fitness Plus, (POWERbreathe International Ltd, UK) [Inspiratory muscles strengthening], Control
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronary Artery Disease
Regadenoson and Adenosine
The aim of the study is to test the accuracy of Regadenoson to induce maximal and steady state hyperemia as compared to central venous infusion of adenosine for assessing fractional flow reserve.
- Trial name
- NCT01809743
- Testing
- Regadenoson central -central, Regadenoson peripheral - peripheral, Regadenoson central - peripheral
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Lokien van Nunen
Congenital Heart Disease, Coarctation of Aorta
An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease
The purpose of this two-way cohort study was to explore whether an integrated prenatal and postnatal treatment model for neonates with critical congenital heart disease (CCHD) could be effective in avoiding preoperative…
- Conditions
- Congenital Heart Disease, Coarctation of Aorta, Aortic Stenosis, Pulmonary Atresia
- Trial name
- NCT06768008
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
Atherosclerosis
Jetstream in Treatment of Occlusive Atherosclerotic Lesions in the SFA and/or PPA
This clinical study is a prospective, non-randomized, multicenter, single-arm study to demonstrate the acceptable safety and performance of the JETSTREAM™ Atherectomy System (Jetstream) used during percutaneous peripheral…
- Trial name
- NCT03455855
- Testing
- Jetstream System
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Boston Scientific Corporation
Peripheral Arterial Disease(PAD)
Korean Vascular Intervention Society Multicenter Registry Study on Outcomes of Endovascular Therapy in Lower Limb Artery Diseases (K-VIS ELLA): (A Retrospective & Prospective Observational Study)
1. Study design: multicenter retrospective and prospective observational study 2. Study Cohort : 1. Retrospective cohort: This cohort retrospectively enrolls patients with lower extremity artery disease who underwent endovascular…
- Trial name
- NCT02748226
- Testing
- endovascular treatment
- Where
- South Korea
- Volunteers
- 12,000 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Cerebrovascular Disease
RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease
The objective of this study is to evaluate an antibiotic therapy called Rifalazil to determine its effect on hardening of the carotid arteries.
- Conditions
- Coronary Artery Disease, Cerebrovascular Disease, Peripheral Vascular Disease
- Trial name
- NCT00385385
- Testing
- Rifalazil
- Where
- 6 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- ActivBiotics
Coronary Artery Disease, Myocardial Perfusion Abnormalities
Regadenoson Real Time Perfusion Imaging Trial-Optison
The purpose if this study is to examine how effective Regadenoson is in detecting coronary artery disease during a stress echocardiogram when Optison is administered.
- Trial name
- NCT01489176
- Testing
- Regadenoson; Optison
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Coronary Artery Disease (CAD), Peripheral Arterial Disease
A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease
The study is a Phase 2a, randomized, double-blind, placebo-controlled, sequential cohort study to evaluate the pharmacodynamics (PD), safety and pharmacokinetics (PK) of multiple doses of SRSD107 in participants with coronary…
- Trial name
- NCT07318155
- Testing
- SRSD107, 0.9 % sodium chloride
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Sirius Therapeutics Co., Ltd.
Cardiovascular Risk Assessment
Prognosis of Type 2 Diabetic Patients
The study will include 1200 patients with type 2 diabetes and angiographically documented coronary artery disease and 600 matched non-diabetic patients without type 2 diabetes.
- Trial name
- ARTEMIS (NCT01426685)
- Where
- Finland
- Volunteers
- 1,880 people
- Sponsor
- University of Oulu
Coronary Artery Disease
Evaluation of Myocardial Perfusion Reserve
The proposed study is to validate a non-invasive imaging technique to evaluate the myocardial perfusion reserve in comparison with a validated invasive technique, the measure of coronary flow reserve (CRF) with thermodilution.
- Trial name
- EVARESERVE (NCT02773043)
- Testing
- CZT SPECT camera
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease
Desflurane Versus Propofol Anesthesia for Off-Pump CABG
The purpose of this study is to prove if anesthesia maintained with the inhaled volatile anesthetic desflurane is superior to the intravenously applied propofol anesthesia in off-pump coronary artery bypass grafting (OP-CABG)…
- Trial name
- NCT00528515
- Testing
- Diprivan (propofol), Astra-Zeneca, Suprane (desflurane), Baxter
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Coronary Artery Disease, Ischemic Heart Disease
Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent
The aim of the Danish Organization for Randomized Trials with Clinical Outcome (SORT OUT) is to compare the safety and efficacy of the sirolimus eluting ORSIRO stent and the biolimus-eluting NOBORI stent in a population-based…
- Trial name
- SORT OUT VII (NCT01879358)
- Testing
- Drug-eluting stent
- Where
- Denmark
- Volunteers
- 2,314 people
- Sponsor
- Odense University Hospital
Carotid Artery Stenosis, Acute Ischemic Stroke
Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF the MicronEt-covered CGUARD (SAFEGUARD-STROKE)
Prospective, single-center, clinical registry of patients with acute stroke of carotid artery bifurcation origin undergoing endovascular treatment using the Micronet-covered CGUARD Stent to seal the culprit lesion under proximal…
- Trial name
- NCT05195658
- Testing
- Thrombectomy and Stenting under neuroprotection
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- John Paul II Hospital, Krakow
Intermittent Claudication, Peripheral Arterial Disease
Transcutaneous Electrostimulation for Intermittent Claudication Supervised Walking Therapy for Intermittent cLAudication
Prospective mono-centric trial on patients with peripheral arterial disease and intermittent claudication that receive supervised exercise therapy (group 1) vs.
- Trial name
- TESLA (NCT03512912)
- Testing
- transcutaneous electrical calf muscle stimulation + supervised walking therapy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Renal Artery Stenosis
Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study)
Renal atherosclerotic stenosis (RAS) is a prevalent cause of secondary hypertension (HT). Since there are still uncertainties as to whether and in what patients revascularization by means of percutaneous renal angioplasty (PTRAS)…
- Trial name
- METRAS (NCT01208714)
- Testing
- Optimal medical therapy, revascularization
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Hospital Padova
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