Clinical trials: Ocd
Postpartum Obsessive Compulsive Disorder
Transcranial Magnetic Stimulation as a Treatment for Postpartum Obsessive Compulsive Disorder
The goal of this clinical trial is to learn if accelerated transcranial magnetic stimulation (TMS) is a feasible treatment for obsessive compulsive disorder that worsens or starts within 12 months of childbirth.
- Trial name
- Project MOM (NCT07571187)
- Testing
- Accelerated Continuous Theta Burst Stimulation (cTBS)
- Volunteers
- 15 people
- Sponsor
- Butler Hospital
Alcoholism, Anxiety Disorders
Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety
Alcohol use disorders (AUDs) are a major problem facing our society. Their treatment is complex, and involves multiple behavioral and pharmacotherapy interventions.
- Conditions
- Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00352469
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Creighton University
Obsessive-Compulsive Disorder, Burns
OCD Among Patients With Burns
Estimating the prevalence of OCD symptoms among patients with burns
- Trial name
- NCT00294983
- Where
- Israel
- Sponsor
- Sheba Medical Center
Obsessive-compulsive Disorder
Efficacy and Adverse Events of Bilateral Single-shot VC/VS Gamma Capsulotomy for OCD: a Pilot Study
Up to 40% of Obsessive-Compulsive Disorder (OCD) patients do not respond to conventional treatments (medications or behavior therapy). For some of them, a neurosurgical treatment can be indicated.
- Trial name
- NCT02433886
- Testing
- Gamma Ventral Capsulotomy
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- University of Sao Paulo General Hospital
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a highly disabling psychiatric illness, characterized by obsessional thoughts that cause patients to perform time-consuming and distressing compulsive rituals.
- Trial name
- RCT_TOC_16 (NCT03677947)
- Testing
- Exposure and response prevention, Inference-based cognitive therapy
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Obsessive Compulsive Disorder, Healthy
Inhibitory Control of the Mind : Neural Bases and Impact for Obsessive-compulsive Disorders
Mental-health conditions affect million people worldwide. The economic burden of mental illness is enormous and the economic health of both developing and developed nations will depend on controlling the staggering growth in…
- Trial name
- SUPTOC (NCT02850393)
- Testing
- Functional magnetic resonance imaging, behavioral measures, physiological measurements
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Obsessive-Compulsive Disorder
European Study of Quality of Life in Resistant OCD Patients Treated by STN DBS
Obsessive-Compulsive Disorder (OCD) is among the most disabling psychiatric disorders as more than 40% of patients are resistant to the standard pharmacological and psychotherapy approaches and about 10% show severe disability…
- Trial name
- EQOLOC (NCT02844049)
- Testing
- Deep Brain Stimulation
- Where
- 8 sites in France, Germany and 2 more
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Obsessive-Compulsive Disorder
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
Pediatric obsessive compulsive disorder (OCD) is a relatively common and often severe condition that can become chronic if untreated.
- Trial name
- DCS (NCT01687140)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Trichotillomania
Cognitive Behavioral Treatment of Pediatric Trichotillomania
This study will compare the effectiveness of cognitive-behavior therapy (CBT) to a minimal attention control (AC) condition for treatment of pediatric trichotillomania (TTM).
- Trial name
- NCT00043563
- Testing
- Cognitive-Behavior Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder
Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder
This study will determine the effectiveness of adding motivational interviewing to cognitive behavioral therapy, consisting of exposure and ritual prevention, in improving treatment outcomes in people with obsessive-compulsive…
- Trial name
- NCT00316316
- Testing
- Motivational interviewing plus exposure and response prevention (MI plus EX/RP), Exposure and response prevention (EX/RP)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-compulsive Disorder
Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder
This study is to assess the efficacy and safety of two doses of ondansetron (0.5 mg and 0.75 mg) relative to placebo when administered twice daily as adjunctive therapy for adult patients with Obsessive-Compulsive Disorder (OCD)…
- Trial name
- NCT01275248
- Testing
- Ondansetron
- Where
- 32 sites in United States, Mexico
- Volunteers
- 130 people
- Sponsor
- Transcept Pharmaceuticals
Body Dysmorphic Disorder
Fluoxetine in Pediatric Body Dysmorphic Disorder
This trial will study the effectiveness of the medication fluoxetine for children and adolescents ages 16 and younger with BDD who qualify.
- Trial name
- FDA BDD (NCT00245635)
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Montefiore Medical Center
Obsessive Compulsive Disorder
Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD
This study will examine the feasibility and potential efficacy of augmenting SRIs with minocycline. The study will assess whether the addition of minocycline leads to measurable changes in striatal glutamate (Glu) levels.
- Trial name
- NCT01695291
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- New York State Psychiatric Institute
OCD
Effect of N-acetylcysteine as Add on Therapy With SSRI in Moderate to Severe OCD Patients
Title: Effect of n-acetylcysteine as add-on therapy with Selective Serotonin Reuptake Inhibitors in moderate to severe Obsessive Compulsive Disorder patients.
- Trial name
- NCT04904952
- Testing
- N-acetylcysteine tablet 600mg
- Where
- 2 sites in Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Obsessive Compulsive Disorder
St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.
The purpose of this study is to determine the effectiveness of St. John's Wort as compared to placebo (an inactive substance) in the treatment of outpatients with obsessive compulsive disorder.
- Trial name
- NCT00035438
- Testing
- St. John's Wort
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
OCD
Multi-session, Personalized Cognitive Bias Modification for Thought-Action-Fusion
Thought-Action-Fusion (TAF) is a cognitive bias that posits (1) having unwanted thoughts is morally equivalent to acting upon the thoughts (TAF-Moral; e.g., "Thinking about harming a child is as immoral as actually harming a…
- Trial name
- NCT06731426
- Testing
- CBM-TAF, CBM-SMP
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Han Joo Lee
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Obsessive-Compulsive Disorder
Four-day Intensive Treatment Versus Standard Cognitive Behavioral Therapy for Adults With Obsessive-compulsive Disorder
The goal of this clinical trial is to compare a novel, condensed version of cognitive behavioral therapy (Bergen 4-Day Treatment, B4DT) to the gold standard psychological treatment (gold-standard CBT) for obsessive compulsive…
- Trial name
- NCT05608278
- Testing
- Bergen 4-Day Treatment (B4DT), Gold standard cognitive behavioral therapy (gold standard CBT)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Digital Mindfulness-Based Therapy for Obsessive-Compulsive Disorder
This randomized controlled trial aims to evaluate the effects of digital mindfulness-based therapy in people with obsessive-compulsive disorder and to explore its possible psychological and neurophysiological mechanisms.
- Trial name
- dMBT-OCD (NCT07701616)
- Testing
- Digital Mindfulness-Based Therapy, Routine Pharmacological Treatment
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- Central South University
Obsessive Compulsive Disorder (OCD)
Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial
Obsessive-compulsive disorder is a chronic and disabling mental disorder. Among them, 40-60% of obsessive-compulsive disorder patients do not respond to the current first-line drug treatment and/or psychological therapy.
- Trial name
- NCT07811778
- Testing
- Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Mental Health Center