Clinical trials: Ocd
Parkinson Disease, Dystonia
Physiological Brain Atlas Development
Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.
- Conditions
- Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder
- Trial name
- NCT01210534
- Testing
- No intervention
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Ohio State University
Obsessive - Compulsive Disorder
Psilocybin for Treatment of OCD-2
Previous research indicates that psilocybin, a drug that changes activity in brain areas believed to be involved in obsessive-compulsive disorder (OCD), might improve treatment for, and improve lives of, people diagnosed with…
- Trial name
- NCT06992999
- Testing
- Low Dose Psilocybin, High Dose Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Francisco A Moreno
Obsessive-Compulsive Disorder
Efficacy of Treatment With Pramipexole or Risperidone in Patients With Refractory Obsessive-compulsive Disorder (OCD)
This is a phase 2, randomized, controlled clinical trial to study the efficacy of pramipexol or risperidone in the treatment of refractory ODC patients.
- Trial name
- OCD-RT (NCT05401019)
- Testing
- Pramipexole, Risperidone
- Sponsor
- Clinical Academic Center (2CA-Braga)
Impulse Control Disorders
Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania
The purpose of this study is to assess the extent of symptom remission in patients with trichotillomania following treatment with sertraline and/or behavior therapy.
- Trial name
- NCT00118014
- Testing
- Sertraline, Habit Reversal Training
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Obsessive Compulsive Disorder
Efficacy of Treatment for Obsessive Compulsive Disorder
The purpose of these questionnaires is to give us an overview of how OCD has affected your life and perhaps also to give us some clues about things that may have set you up to experience OCD.
- Trial name
- NCT00457028
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obsessive Compulsive Disorder
Ondansetron Augmentation in Treatment-resistant OCD
The aim of this study is to evaluate whether ondansetron augmentation to SSRI will improve and ondansetron discontinuation will result in worsening of obsessive compulsive symptoms among obsessive compulsive disorder resistant…
- Trial name
- NCT01303536
- Testing
- Ondansetron
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Institute of Neuroscience, Florence, Italy
Obsessive-Compulsive Disorder
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
This study aims to investigate the effects of oral psilocybin on OCD symptomatology and provide the first evidence of the neural mechanism that may mediate psilocybin's purported therapeutic effects on OCD.
- Trial name
- NCT03356483
- Testing
- Psilocybin (0.25mg/kg), Niacin (250mg)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Yale University
Trichotillomania, Hair Pulling Disorder
Milk Thistle in Trichotillomania in Children and Adults
The goal of the proposed study is to evaluate the efficacy and safety of silymarin (milk thistle) in children and adults with trichotillomania.
- Trial name
- NCT02473913
- Testing
- Milk Thistle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder
Understanding How Ketamine Brings About Rapid Improvement in OCD
The purpose of this study is to understand how ketamine brings about rapid improvement in Obsessive-Compulsive Disorder (OCD) symptoms.
- Trial name
- MKET (NCT02624596)
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited…
- Trial name
- NCT07065669
- Testing
- Dorsal medial Prefrontal Cortex intermittent theta burst stimulation, cTBS to ROFC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Obsessive-Compulsive Disorder
Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
This study will examine the way cognitive behavioral therapy changes the structure of the brain in patients with obsessive-compulsive disorder and will thereby determine what makes cognitive behavioral therapy an effective…
- Trial name
- NCT00748761
- Testing
- Cognitive Behavioral Therapy (CBT), Waitlist
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Trichotillomania
Stepped Care in the Treatment of Trichotillomania
Trichotillomania (TTM), repetitive pulling out of one's own hair to the extent that noticeable hair loss occurs, is a distressing condition interfering substantially with functioning and quality of life.
- Trial name
- NCT01118637
- Testing
- StopPulling.com
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- American University
Obsessive-compulsive Disorder
Developing Computerised CBT for Adults With OCD
The study aims to pilot a new computerised cognitive behavioural therapy programme for a small case series of adults with obsessive-compulsive disorder.
- Trial name
- CCBT (NCT02398045)
- Testing
- Computerised CBT for OCD
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- Institute of Psychiatry, London
Advanced Parkinson's Disease, Refractory Epilepsy
An Automated Navigation System for Deep Brain Electrode Implantation
1. Analysis of the correlation between imaging and electrophysiological signals. 2. Real time analysis method for optimal implantation position. 3. Simultaneous Imaging and electrophysiology navigation. 4.
- Conditions
- Advanced Parkinson's Disease, Refractory Epilepsy, Obsessive-compulsive Disorder
- Trial name
- NCT06396494
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tiantan Hospital
Obsessive-Compulsive Disorder
Pharmaco(Epi)Genetic, Proteomic, and Microbiomic Study of Obsessive-Compulsive Disorder
The purpose of this study is to determine whether pharmaco(epi)genetic study predict selective serotonin reuptake inhibitor (SSRI) responsiveness in advance before the appearance of the drug effect until 4 months(16 weeks), 6…
- Trial name
- NCT02431845
- Testing
- SSRIs
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Severance Hospital
Obsessive-Compulsive Disorder
Deep Brain Stimulation for Treatment-Resistant Obsessive Compulsive Disorder
This study will evaluate the use of Deep Brain Stimulation (DBS) to reduce symptom severity and enhance the quality of life for patients with treatment-resistant obsessive compulsive disorder (OCD).
- Trial name
- NCT00057603
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Osteochondritis Dissecans
Use of Demineralised Bone Matrix (DBX) in Osteochondritis Dissecans (OCD)
This is a 1:1 randomised pilot study in 30 patients in 1 site in Helsinki, Finland. The investigators hypothesize that function, pain, type and quality of cartilage in adult patients with osteochondritis dissecans of the knee…
- Trial name
- NCT01283737
- Testing
- DBX Putty, Mosaicplasty
- Where
- Finland
- Sponsor
- Synthes GmbH
Obsessive-Compulsive Disorder
Safety and Effectiveness of Capsulotomy in Refractory OCD
Obsessive-compulsive disorder (OCD) is a severely disabling psychiatric disorder with a worldwide lifetime prevalence of 2-3% (Islam et al., 2015).Despite the efficacy of pharmacological and behavioural treatment methods for most…
- Trial name
- NCT02375152
- Testing
- Anterior Capsulotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
The investigators are examining whether difficulties with cognitive control (i.e., the ability to stop one's thought process and shift attention) is a common problem across three types of repetitive, negative thinking: obsessions…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT03414619
- Testing
- Cognitive Control Tasks and Script Driven Imagery
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder…
- Trial name
- NCT04548609
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital