Clinical trials: Ocd
Obsessive-Compulsive Disorder
Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors
OCD patients are assessed before and after treatment using diagnostic tools, rating scales neuropsychological assessment and functional and structural MR-scans.
- Trial name
- NCT00792038
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obsessive-Compulsive Disorder
Exposure and Response Prevention Therapy for Obsessive-compulsive Disorder
The purpose of this research study is to evaluate whether Exposure and Response Prevention Therapy (ERP) can help adults with obsessive-compulsive disorder (OCD) in China following a training of professionals and ongoing…
- Trial name
- NCT02602886
- Testing
- Exposure and Response Prevention Therapy
- Where
- 5 sites in China
- Volunteers
- 48 people
- Sponsor
- Ruijin Hospital
Trichotillomania, Alexithymia
Online Treatment of Trichotillomania
Online study for patients with trichotillomania. 4 main hypothesis. 1. Alexithymia and Trichotillomania correlated and regression analyses find association between them 2.
- Conditions
- Trichotillomania, Alexithymia, Quality of Life
- Trial name
- NCT02044237
- Testing
- Decoupling, Progressive relaxation
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- University of Zurich
Obsessive-Compulsive Disorder
TMS-induced Plasticity Improving Cognitive Control in OCD
Repetitive transcranial magnetic stimulation (rTMS) has been shown in several previous clinical trials to be an effective treatment for obsessive-compulsive disorder (OCD).
- Trial name
- TIPICCO (NCT03667807)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Trichotillomania
Cognitive Behavioral Group Therapy for Trichotillomania (Hair Pulling Disorder)
This study aims at evaluating the effectiveness of group-based cognitive behavioral therapy for trichotillomania at three clinical sites in Norway.
- Trial name
- NorTriP (NCT02747771)
- Testing
- Cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Obsessive-Compulsive Disorder
Effect of the French Version If the Metagognitive Bibliotherapy Program "MYMCT" on Obsessive-compulsive Symptoms
Obsessive-compulsive disorder (OCD) is a psychiatric illness characterized by the presence of obsessions and/or compulsions. Without effective treatment, symptoms tend to worsen and become chronic.
- Trial name
- M-TOC (NCT06494735)
- Testing
- MyMCT
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obsessive-Compulsive Disorder
Interpretation Bias as a Mechanism of Treatment Response in OCD
This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD).
- Trial name
- NCT05224414
- Testing
- Cognitive bias modification for interpretation bias, Psychoeducation
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Mclean Hospital
Obsessive-Compulsive Disorder
Cortical Stimulation to Treat Obsessive Compulsive Disorder
The purpose of this study is to identify abnormal brain signals associated with Obsessive Compulsive Disorder (OCD) and psychiatric symptoms and to investigate novel therapeutic stimulation sites.
- Trial name
- NCT04958096
- Testing
- Standard Therapeutic Deep Brain Stimulation, Cortical Stimulation for PFC, Cortical Stimulation for ACC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Obsessive Compulsive Disorder, Major Depressive Disorder
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH.
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder, Epilepsy
- Trial name
- NCT01590862
- Testing
- Deep Brain Stimulator
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)
The primary aim of this study is to learn about who is most likely to benefit from guided self-help (GSH) for obsessive-compulsive disorder (OCD).
- Trial name
- NCT01659125
- Testing
- "OCFighter"
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hartford Hospital
OCD
Light Therapy for Obsessive-compulsive Disorder (OCD)
The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later).
- Trial name
- KLTO (NCT06720090)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive-Compulsive Disorder
The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder
To investigate the neuro-mechanisms underpinning persistent avoidance in OCD patients
- Trial name
- AvoidOCD (NCT04685018)
- Testing
- fMRI acquisition
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obsessive-Compulsive Disorder
Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)
This pilot study is proposed to determine the acceptability, feasibility and potential efficacy of ketamine, a medication that modulates glutamate in the brain, as a rapid treatment for obsessive-compulsive disorder (OCD)…
- Trial name
- NCT02422290
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Evaluating Unilateral Deep Brain Stimulation in Patients With Obsessive Compulsive Disorder
The investigators previously showed that deep brain stimulation (DBS) in the bed nucleus of the stria terminalis (BNST) reduces symptoms in patients with severe obsessive-compulsive disorder (OCD).
- Trial name
- NCT03894397
- Testing
- Electrical stimulation of the BNST
- Where
- Belgium
- Volunteers
- 9 people
- Sponsor
- KU Leuven
Obsessive Compulsive Disorder (OCD)
Long-term Follow-up in Patients With Deep Brain Stimulation (DBS) for Obsessive Compulsive Disorder (OCD).
For this human research, 17 treatment-refractory OCD patients who already received DBS implants for treatment refractory OCD between June 1998 and October 2007 will be included.
- Trial name
- NCT01879254
- Testing
- Deep Brain Stimulation
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation
Continuous Theta-Burst Stimulation for Obsessive-Compulsive Disorder: An Open-Label Study
This single-arm, open-label study evaluates short-term symptom improvement and tolerability of continuous theta-burst stimulation (cTBS), a non-invasive brain stimulation technique, in adults with obsessive-compulsive disorder…
- Conditions
- Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation, Electroencephalography
- Trial name
- NCT07896837
- Testing
- Continuous Theta-Burst Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Hoarding Disorder, Hoarding
Neuromodulation for Comorbid Hoarding Disorder and Depression
The primary goal of this study is to evaluate whether intermittent theta burst stimulation (iTBS) is effective for treating depression in people who have depression and chronic hoarding disorder (HD).
- Conditions
- Hoarding Disorder, Hoarding, Depression
- Trial name
- NCT05985356
- Testing
- iTBS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Diego
Obsessive-Compulsive Disorder
Psychiatric Comorbidity and Quality of Life in Patients With Obsessive Compulsive Disorder(Case Control Study )
Psychiatric Comorbidity and quality of life in patients with Obsessive Compulsive Disorder(case control study )
- Trial name
- NCT05105581
- Testing
- Quality of life scale
- Volunteers
- 37 people
- Sponsor
- Assiut University
Obsessive-Compulsive Disorder
N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Pediatric Obsessive-Compulsive Disorder (OCD) affects 1-3% of children. The investigators currently have effective first-line interventions for pediatric OCD such as Cognitive Behavioral Therapy (CBT) and pharmacotherapy with…
- Trial name
- NCT01172275
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Yale University
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Adjunctive Celecoxib in Childhood-onset OCD Study
This is a randomized, controlled, single-centre phase II superiority trial to determine the efficacy of 12 weeks of celecoxib (50 mg or 100 mg orally twice daily, dosed based on weight) compared to placebo as an adjunct to…
- Trial name
- ACE-OCD (NCT04673578)
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia