Clinical trials: Ocd
Social Anxiety Disorder, Specific Phobia
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program.
- Conditions
- Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder
- Trial name
- NCT02305537
- Testing
- McLean Anxiety Mastery Program
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Mclean Hospital
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Obsessive-Compulsive Disorder
Identifying Local Field Potential Biomarkers for Obsessive-compulsive Disorder Treatment With Deep Brain Stimulation
Obsessive-compulsive disorder (OCD) is a complex and severe mental illness characterized by multiple symptoms and is considered a leading cause of non-fatal health loss.
- Trial name
- DBS OCD (NCT06542224)
- Testing
- Deep Brain stimulation
- Where
- 4 sites in China
- Volunteers
- 16 people
- Sponsor
- West China Hospital
Excoriation (Skin-Picking) Disorder
A RCT of an AEBT Website for Adults With Skin Picking
The goal of this clinical trial is to test an online intervention for adults with excoriation disorder (skin picking). The main questions it aims to answer are: 1.
- Trial name
- NCT05989737
- Testing
- Acceptance-Enhanced Behavior Therapy
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Utah State University
Obsessive-Compulsive Disorder
Cognitive Training in Obsessive Compulsive Disorder
This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm.
- Trial name
- CTOCD (NCT02818088)
- Testing
- n-Back (Cognitive Training)
- Where
- South Africa
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Obsessive-Compulsive Disorder, Obsessive-Compulsive Behavior
Rituximab Treatment for Psychosis And/or Obsessive Compulsive Disorder with Probable Immune System Involvement
The primary objective for this study is to evaluate whether Rituximab as compared to placebo is a clinically effective treatment for a subgroup of patients suffering from psychosis and/or obsessive-compulsive disorder (OCD) or…
- Conditions
- Obsessive-Compulsive Disorder, Obsessive-Compulsive Behavior, Schizophrenia, Delusional Disorder
- Trial name
- Ra-P-OCD (NCT04323566)
- Testing
- Rituximab
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University Hospital
Obsessive-Compulsive Disorder (OCD)
Open Label Trial of Rapastinel (Formerly GLYX-13) in Individuals With Obsessive-Compulsive Disorder
This research study tests whether GLYX-13 - an experimental drug that acts on a brain receptor called NMDA - can decrease symptoms of OCD within hours. This is not a treatment study.
- Trial name
- NCT02267629
- Testing
- Rapastinel (formerly GLYX-13)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder
Adjunctive Glycine for Obsessive Compulsive Disorder
The purpose of this study is to determine whether individuals with obsessive compulsive disorder who will take a preparation of the amino acid glycine in addition to their current treatment, may experience improvement in their…
- Trial name
- NCT00405535
- Testing
- glycine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Obsessive-Compulsive Disorder
Is There a New Gold Standard for the Treatment of Obsessive-Compulsive Disorder?
Obsessive Compulsive Disorder is a highly debilitating condition with a lifetime prevalence of 2%-3%, and a notable percentage of patients (40-60%) have a partial or no response to medications.
- Trial name
- NCT04436952
- Testing
- H7 coil, Cool D-B80, Exposure Response Prevention (ERP)
- Where
- Canada
- Sponsor
- University of Alberta
Obsessive-Compulsive Disorder, EEG With Periodic Abnormalities
EEG Results of Deep TMS in Patients With OCD
Obsessive Compulsive Disorder (OCD) is a psychiatric disorder in which involuntary thoughts and irresistible behaviors are seen and its prevalence affects 2%-3% of the general population.
- Trial name
- NCT05188833
- Testing
- Deep Transcranial Magnetic Stimulation, Paroxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
OCD
Effects of Sertraline on Brain Connectivity in Adolescents With OCD
The investigators will examine how treatment with sertraline for 12 weeks impacts frontal-striatal-thalamic circuitry (FSTC) in this OCD sample.
- Trial name
- NCT02797808
- Testing
- Sertraline, No Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obsessive-Compulsive Disorder
Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder
OBJECTIVES: I. Evaluate the efficacy of intravenous versus oral pulse loading of clomipramine (CMI) followed by a 12-week course of maintenance therapy in patients with obsessive compulsive disorder.
- Trial name
- NCT00004310
- Testing
- Clomipramine
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- National Center for Research Resources (NCRR)
Hoarding Disorder
Comparison of Treatment for Hoarding Disorder
This study proposes to compare two forms of treatment for Hoarding Disorder (HD), a common and impairing neuropsychiatric syndrome that has a profound impact on the lives and functioning of individuals, families, and society.
- Trial name
- NCT02040805
- Testing
- Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
- Where
- 2 sites in United States
- Volunteers
- 323 people
- Sponsor
- University of California, San Francisco
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive Compulsive Disorder
Internet Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
The main aim of this study is to test whether cognitive behavior therapy could be effective in treating obsessive compulsive disorder.
- Trial name
- NCT01348529
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Karolinska Institutet
Obsessive Compulsive Disorder (OCD)
Exploring the Efficacy of Accelerated Transcranial Direct Current Stimulation (tDCS) as Adjunct to Pharmacotherapy in the Treatment of Obsessive-compulsive Disorder
This study will evaluate the decision-making ability and therapeutic effects of accelerated Transcranial Direct Current Stimulation (tDCS) as adjunct to pharmacotherapy in obsessive-compulsive disorder (OCD) patients, and the…
- Trial name
- NCT07115615
- Testing
- high-definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-compulsive Disorder
Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder
Randomized controlled non-inferiority trial comparing therapist-guided Internet-based Cognitive behavioral therapy (ICBT), self-guided ICBT, and individual face-to-face (f2f) CBT for Obsessive-Compulsive Disorder (OCD) in adults.
- Trial name
- NCT02541968
- Testing
- Cognitive-behavioral therapy (face-to-face), Internet-based Cognitive-behavioral therapy, Internet-based Cognitive-behavioral therapy without therapist support
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Trichotillomania (Hair-Pulling Disorder)
Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults
This trial aims to evaluate the efficacy, safety and tolerability of valbenazine, titrated to the subject's optimal dose of 40mg or 80mg, administered once daily, for 12 weeks, for the treatment of trichotillomania (TTM) in a…
- Trial name
- NCT05207085
- Testing
- Valbenazine Oral Capsule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Obsessive Compulsive Disorder, Stepped Care Cognitive Behavioral Therapy
Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder
The purpose of this research study is to determine how well children with OCD can be helped using therapy that requires less clinic visits.
- Trial name
- SC-CBT (NCT01981317)
- Testing
- Stepped Care Cognitive Behavioral Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of South Florida
Hoarding Disorder
Enhancing Attention in Adults With Compulsive Hoarding
Available data suggest that compulsive hoarders have cognitive deficits, particularly with sustaining attention that might contribute their hoarding symptoms.
- Trial name
- NCT01100268
- Testing
- Methylphenidate ER
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- New York State Psychiatric Institute