Clinical trials: Ocd
Obsessive Compulsive Disorder (OCD)
Priming CBT With rTMS for OCD
Cognitive behavioural therapy (CBT), incorporating exposure/response prevention (ERP) and cognitive therapy, is considered the gold-standard first-line treatment for obsessive-compulsive disorder (OCD).
- Trial name
- NCT06840951
- Testing
- rTMS, CBT
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obsessive Compulsive Disorder
Addition of Quetiapine in Obsessive Compulsive Disorder - Westenberg Study
Quetiapine (Seroquel ®), an atypical antipsychotic registered for use in schizophrenia, which has a very low propensity of extrapyramidal and endocrine side-effects, has also been studied as an adjunct in OCD.
- Trial name
- NCT00318539
- Testing
- Quetiapine
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
COPD
A Prospective Observational Study of the Breath Responsive Variable Bolus Oxygen Conserving Device
Evaluate subjects in an prospective observational study Subjects will be administered scientifically validated questionnaires Evaluate Quality Improvement and Oxygen Utilization Improvements. 1.
- Trial name
- BRVB-OCD (NCT02627599)
- Testing
- Breath Responsive Variable Bolus Oxygen Conserving Device
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- StratiHealth
Obsessive Compulsive Disorder (OCD)
The Effects and Neural Mechanisms of Vitamin D and Iron-Immune Homeostasis on Inhibitory Control in Obsessive-Compulsive Disorder
This study is a randomized, open-labled, no-treatment-controlled clinical trial designed to investigate the effects of vitamin D and iron-immune homeostasis on inhibitory control and the underlying neural mechanisms in patients…
- Trial name
- NCT07763977
- Testing
- Calcitriol and Iron Supplements
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial People's Hospital
Obsessive-Compulsive Disorder
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obsessive-Compulsive Disorder
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Trial name
- NCT04211402
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Obsessive-Compulsive Disorder, Psychiatric Disorder
Glucose Consumption During Deep Brain Stimulation With Functional [18F]FDG-Brain-PET in Obsessive-Compulsive Disorder
The purpose of this randomized, sham-controlled study is to evaluate the effectiveness of DBS therapy in individuals suffering from severe OCD and to investigate DBS treatment with functional [18F]FDG-Brain-PET.
- Trial name
- OCDBS (NCT05577598)
- Testing
- Implantation of a DBS therapy system
- Where
- Austria
- Volunteers
- 8 people
- Sponsor
- Medical University of Vienna
Obsessive-Compulsive Disorder
Deep Brain Stimulation and Obsessive-compulsive Disorder
Obsessive-compulsive disorder (OCD) is a relatively common psychiatric condition, which is classically treated by antidepressant medications in combination with psychotherapies.
- Trial name
- STOC2 (NCT01329133)
- Testing
- Deep Brain Stimulation (DBS)
- Where
- 14 sites in France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Bordeaux
Obsessive-Compulsive Disorder
The Gut Microbiota in Obsessive-Compulsive Disorder
This study will examine the gut microbiota and serum inflammatory markers in patients with Obsessive-Compulsive Disorder vs. healthy controls.
- Trial name
- NCT02285699
- Testing
- SSRIs
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- McMaster University
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Obsessive-Compulsive Disorder
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD).
- Trial name
- LIFU (NCT05467085)
- Testing
- BX Pulsar 1002
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Obsessive-compulsive Disorder
Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood
Obsessive-compulsive disorders are very damaging illnesses that can already manifest in childhood and adolescence. With an average prevalence from 1 - 3%, they are one of the most frequently diagnosed psychiatric illness in these…
- Trial name
- NCT04723485
- Where
- Switzerland
- Volunteers
- 625 people
- Sponsor
- Susanne Walitza
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Treatment of Obsessive Compulsive Disorder in Children
This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive…
- Trial name
- NCT00074815
- Testing
- Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- Duke University
Obsessive-Compulsive Disorder
2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD
The purpose of this study is to find out if D-Cycloserine (DCS), taken at the same time as a child gets cognitive behavioral therapy (CBT) can help children with pediatric obsessive-compulsive disorder.
- Trial name
- NCT01404208
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Deep Brain Stimulation of the Bilateral Habenula for Treatment-Refractory Obsessive-Compulsive Disorder
Deep brain stimulation (DBS) offers an effective and safe treatment for patients with debilitating, otherwise treatment-refractory obsessive-compulsive disorder(OCD).
- Trial name
- NCT03463590
- Testing
- Bilateral surgical implantation of DBS system to habenula
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Ruijin Hospital
Obsessive Compulsive Disorder
Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder
OBJECTIVE: The objective of this study is to compare the effect and safety of conventional dose (20mg) and high dose (40mg) of escitalopram in patients with obsessive-compulsive disorder (OCD).
- Trial name
- NCT00723060
- Testing
- escitalopram
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Obsessive - Compulsive Disorder
Accelerated rTMS in Hospitalized Patients With OCD: a Feasibility and Mechanistic Study
This study investigates a new treatment approach for Obsessive-Compulsive Disorder (OCD), a condition characterized by unwanted repetitive thoughts and behaviors.
- Trial name
- arTMS-OCD (NCT07135414)
- Testing
- iTBS, dTMS, ERP
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Obsessive-Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
This study will evaluate the clinical efficacy of functional Magnetic Resonance Imaging (fMRI) guided 1 Hz repetitive Transcranial Magnetic Stimulation (rTMS) applied to the Supplementary Motor Area (SMA) in OCD patients who have…
- Trial name
- NCT00106249
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder
A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive Disorder
The objective of the first phase of this study is to evaluate the efficacy of fluvoxamine compared to placebo on change in total score of Japanese version of the Children's Yale-Brown Obsessive Compulsive Scale (JCY-BOCS) 10-item…
- Trial name
- NCT01933919
- Testing
- Fluvoxamine maleate
- Volunteers
- 38 people
- Sponsor
- AbbVie
Obsessive Compulsive Disorder (OCD)
Feasibility, Acceptability, and Preliminary Efficacy of a Mobile App (nOCD) for OCD
The purpose of this study is to evaluate the feasibility, acceptability, and potential usefulness of using a mobile application (nOCD) for treatment of obsessive compulsive disorder (OCD) in a sample of 25 adults (ages 18-65) in…
- Trial name
- nOCD (NCT03476902)
- Testing
- Therapist assisted mobile intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- New York State Psychiatric Institute